Identification of FHOD1-binding proteins and mechanisms of FHOD1-regulated actin dynamics

Journal of Cellular Biochemistry

Volumn 92, Issue 1, 2004, Pages 29-41

  Westendorf, Jennifer J ^a   Koka, Sreenivas ^b  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Cyclophilin B; Diaphanous; DIP1; FHOD1; FHOS; Formin; PRKCP1; RACK7; Stress fibers; WISH

Indexed keywords

ACTIN; BINDING PROTEIN; CYCLOPHILIN B; FORMIN HOMOLOGY 2 DOMAIN CONTAINING PROTEIN 1; METHENAMINE; PROTEIN KINASE C BINDING PROTEIN 1; PROTEIN SH3; PROTEIN WASP INTERACTING SH3; SERUM RESPONSE FACTOR; UNCLASSIFIED DRUG; CARRIER PROTEIN; CELL SURFACE RECEPTOR; CYCLOPHILIN; FETOPROTEIN; FHOD1 PROTEIN, HUMAN; MUSCLE PROTEIN; NCKIPSD PROTEIN, MOUSE; NUCLEAR PROTEIN; PEPTIDYLPROLYL ISOMERASE; RECEPTORS FOR ACTIVATED C KINASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ACTIN POLYMERIZATION; ARTICLE; CELL MIGRATION; CYTOSKELETON; GENETIC TRANSCRIPTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; STRESS FIBER; TRANSCRIPTION REGULATION; ANIMAL; CELL LINE; DNA RESPONSIVE ELEMENT; GENETICS; HUMAN; METABOLISM; MOUSE; PROMOTER REGION; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; TRANSACTIVATION; TWO HYBRID SYSTEM; ULTRASTRUCTURE;

ACTINS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CARRIER PROTEINS; CELL LINE; CYCLOPHILINS; FETAL PROTEINS; HUMANS; MICE; MUSCLE PROTEINS; NUCLEAR PROTEINS; PEPTIDYLPROLYL ISOMERASE; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CELL SURFACE; RESPONSE ELEMENTS; STRESS FIBERS; TRANS-ACTIVATION (GENETICS); TWO-HYBRID SYSTEM TECHNIQUES;

EID: 16244379726     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.20031     Document Type: Article

References (47)

1. Alberts AS. 2000. Identification of a carboxy-terminal diaphanous-related formin homology protein autoregulatory domain. J Biol Chem 16:16.
2. Bione S, Sala C, Manzini C, Arrigo G, Zuffardi O, Banfi S, Borsani G, Jonveaux P, Philippe C, Zuccotti M, Ballabio A, Toniolo D. 1998. A human homologue of the Drosophila melanogaster diaphanous gene is disrupted in a patient with premature ovarian failure: Evidence for conserved function in oogenesis and implications for human sterility. Am J Hum Genet 62:533-541.
3. Bubb MR, Senderowicz AM, Sausville EA, Duncan KL, Korn ED. 1994. Jasplakinolide, a cytotoxic natural product, induces actin polymerization and competitively inhibits the binding of phalloidin to F-actin. J Biol Chem 269:14869-14871.
4. Castrillon DH, Wasserman SA. 1994. Diaphanous is required for cytokinesis in Drosophila and shares domains of similarity with the products of the limb deformity gene. Development 120:3367-3377.
5. Chang F, Drubin D, Nurse P. 1997. cdc12p, a protein required for cytokinesis in fission yeast, is a component of the cell division ring and interacts with profilin. J Cell Biol 137:169-182.
6. Copeland JW, Treisman R. 2002. The diaphanous-related formin mDial controls serum response factor activity through its effects on actin polymerization. Mol Biol Cell 13:4088-4099.
7. Coue M, Brenner SL, Spector I, Korn ED. 1987. Inhibition of actin polymerization by latrunculin A. FEBS Lett 213:316-318.
8. de Bernard M, Moschioni M, Napolitani G, Rappuoli R, Montecucco C. 2000. The VacA toxin of Helicobacter pylori identifies a new intermediate filament-interacting protein. Embo J 19:48-56.
9. Ellis PD, Martin KM, Rickman C, Metcalfe JC, Kemp PR. 2002. Increased actin polymerization reduces the inhibition of serum response factor activity by Yin Yang 1. Biochem J 364:547-554.
10. Emmons S, Phan H, Galley J, Chen W, James B, Manseau L. 1995. Cappuccino, a Drosophila maternal effect gene required for polarity of the egg and embryo, is related to the vertebrate limb deformity locus. Genes Dev 9:2482-2494.
11. Evangelista M, Blundell K, Longtine MS, Chow CJ, Adames N, Pringle JR, Peter M, Boone C. 1997. Bni1p, a yeast formin linking cdc42p and the actin cytoskeleton during polarized morphogenesis. Science 276:118-122.
12. Evangelista M, Pruyne D, Amberg DC, Boone C, Bretscher A. 2002. Formins direct Arp2/3-independent actin filament assembly to polarize cell growth in yeast. Nat Cell Biol 4:32-41.
13. Evangelista M, Zigmond S, Boone C. 2003. Formins: Signaling effectors for assembly and polarization of actin filaments. J Cell Sci 116:2603-2611.
14. Fossey SC, Kuroda S, Price JA, Pendleton JK, Freedman BI, Bowden DW. 2000. Identification and characterization of PRKCBP1, a candidate RACK-like protein. Mamm Genome 11:919-925.
15. Fukuda T, Kido A, Kajino K, Tsutsumi M, Miyauchi Y, Tsujiuchi T, Konishi Y, Hino O. 1999. Cloning of differentially expressed genes in highly and low metastatic rat osteosarcomas by a modified cDNA-AFLP method. Biochem Biophys Res Commun 261:35-40.
16. Fukuoka M, Suetsugu S, Miki H, Fukami K, Endo T, Takenawa T. 2001. A novel neural Wiskott-Aldrich syndrome protein (N-WASP) binding protein, WISH, induces Arp2/3 complex activation independent of Cdc42. J Cell Biol 152:471-482.
17. Gasteier JE, Madrid R, Krautkramer E, Schroder S, Muranyi W, Benichou S, Fackler OT. 2003. Activation of the Rac-binding partner FHOD1 induces actin stress fibers via a ROCK-dependent mechanism. J Biol Chem 278:38902-38912.
18. Habas R, Kato Y, He X. 2001. Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel formin homology protein Daam1. Cell 107:843-854.
19. Imamura H, Tanaka K, Hihara T, Umikawa M, Kamei T, Takahashi K, Sasaki T, Takai Y. 1997. Bni1p and Bnr1p: Downstream targets of the Rho family small G-proteins which interact with profilin and regulate actin cytoskeleton in Saccharomyces cerevisiae. Embo J 16:2745-2755.
20. Ishizaki T, Morishima Y, Okamoto M, Furuyashiki T, Kato T, Narumiya S. 2001. Coordination of microtubules and the actin cytoskeleton by the Rho effector mDial. Nat Cell Biol 3:8-14.
21. Koka S, Neudauer CL, Li X, Lewis RE, McCarthy JB, Westendorf JJ. 2003. The formin-homology-domain-containing protein FHOD1 enhances cell migration. J Cell Sei 116:1745-1755.
22. Leader B, Leder P. 2000. Formin-2, a novel formin homology protein of the cappuccino subfamily, is highly expressed in the developing and adult central nervous system. Mech Dev 93:221-231.
23. Leader B, Lim H, Carabatsos MJ, Harrington A, Ecsedy J, Pellman D, Maas R, Leder P. 2002. Formin-2, polyploidy, hypofertility and positioning of the meiotic spindle in mouse oocytes. Nat Cell Biol 4:921-928.
24. Li F, Higgs HN. 2003. The mouse formin mDial is a potent actin nucleation factor regulated by autoinhibition. Curr Biol 13:1335-1340.
25. Lim CS, Park ES, Kim DJ, Song YH, Eom SH, Chun JS, Kim JH, Kim JK, Park D, Song WK. 2001. SPIN90 (SH3 protein interacting with Nek, 90 kDa), an adaptor protein that is developmentally regulated during cardiac myocyte differentiation. J Biol Chem 276:12871-12878.
26. Lynch ED, Lee MK, Morrow JE, Welcsh PL, Leon PE, King MC. 1997. Nonsyndromic deafness DFNA1 associated with mutation of a human homolog of the Drosophila gene diaphanous. Science 278:1315-1318.
27. Maas RL, Zeller R, Woychik RP, Vogt TF, Leder P. 1990. Disruption of formin-encoding transcripts in two mutant limb deformity alleles. Nature 346:853-855.
28. Nakano K, Takaishi K, Kodama A, Mammoto A, Shiozaki H, Monden M, Takai Y. 1999. Distinct actions and co-operative roles of ROCK and mDia in Rho small G protein-induced reorganization of the actin cytoskeleton in Madin-Darby canine kidney cells. Mol Biol Cell 10:2481-2491.
29. Paradis P, MacLellan WR, Belaguli NS, Schwartz RJ, Schneider MD. 1996. Serum response factor mediates AP-1-dependent induction of the skeletal alpha-actin promoter in ventricular myocytes. J Biol Chem 271:10827-10833.
30. Pruyne D, Evangelista M, Yang C, Bi E, Zigmond S, Bretscher A, Boone C. 2002. Role of formins in actin assembly: Nucleation and barbed end association. Science 6:6.
31. Sagot I, Klee SK, Pellman D. 2002. Yeast formins regulate cell polarity by controlling the assembly of actin cables. Nat Cell Biol 4:42-50.
32. Sano K, Hayakawa A, Piao JH, Kosaka Y, Nakamura H. 2000. Novel SH3 protein encoded by the AF3p21 gene is fused to the mixed lineage leukemia protein in a therapy-related leukemia with t(3;11) (p21;q23). Blood 95:1066-1068.
33. Satoh S, Tominaga T. 2001. mDia-interacting protein acts downstream of Rho-mDia and modifies Src activation and stress fiber formation. J Biol Chem 276:39290-39294.
34. Schratt G, Philippar U, Berger J, Schwarz H, Heidenreich O, Nordheim A. 2002. Serum response factor is crucial for actin cytoskeletal organization and focal adhesion assembly in embryonic stem cells. J Cell Biol 156:737-750.
35. Skubitz KM, Skubitz AP. 2003. Differential gene expression in leiomyosarcoma. Cancer 98:1029-1038.
36. Sotiropoulos A, Gineitis D, Copeland J, Treisman R. 1999. Signal-regulated activation of serum response factor is mediated by changes in actin dynamics. Cell 98:159-169.
37. Takeya R, Sumimoto H. 2003. Fhos, a mammalian formin, directly binds to F-actin via a region N-terminal to the FH1 domain and forms a homotypic complex via the FH2 domain to promote actin fiber formation. J Cell Sci 116:4567-4575.
38. Tojo H, Kaieda I, Hattori H, Katayama N, Yoshimura K, Kakimoto S, Fujisawa Y, Presman E, Brooks CC, Pilch PF. 2003. The formin family protein, formin homolog overexpressed in spleen, interacts with the insulin-responsive aminopeptidase and profilin IIa. Mol Endocrinol 17:1216-1229.
39. Tominaga T, Sahai E, Chardin P, McCormick F, Court-neidge SA, Alberts AS. 2000. Diaphanous-related formins bridge Rho GTPase and Src tyrosine kinase signaling. Mol Cell 5:13-25.
40. Wallar BJ, Alberts AS. 2003. The formins: Active scaffolds that remodel the cytoskeleton. Trends Cell Biol 13:435-446.
41. Wasserman S. 1998. FH proteins as cytoskeletal organizers. Trends Cell Biol 8:111-115.
42. Watanabe N, Madaule P, Reid T, Ishizaki T, Watanabe G, Kakizuka A, Saito Y, Nakao K, Jockusch BM, Narumiya S. 1997. p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin. Embo J 16:3044-3056.
43. Watanabe N, Kato T, Fujita A, Ishizaki T, Narumiya S. 1999. Cooperation between mDial and ROCK in Rho-induced actin reorganization. Nat Cell Biol 1:136-143.
44. Westendorf JJ. 2001. The formin/diaphanous-related protein, FHOS, interacts with Rac1 and activates transcription from the serum response element. J Biol Chem 276:46453-46459.
45. Westendorf JJ, Mernaugh R, Hiebert SW. 1999. Identification and characterization of a protein containing formin homology (FH1/FH2) domains. Gene 232:173-182.
46. Woychik RP, Maas RL, Zeller R, Vogt TF, Leder P. 1990. 'Formins': Proteins deduced from the alternative transcripts of the limb deformity gene. Nature 346:850-853.
47. Yayoshi-Yamamoto S, Taniuchi I, Watanabe T. 2000. FRL, a novel formin-related protein, binds to Rac and regulates cell motility and survival of macrophages. Mol Cell Biol 20:6872-6881.