Fixing the Q cycle

Trends in Biochemical Sciences

Volumn 30, Issue 4, 2005, Pages 176-182

  Osyczka, Artur ^a   Moser, Christopher C ^a   Dutton, P Leslie ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

QUINONE DERIVATIVE; SEMIQUINONE; UBIQUINOL CYTOCHROME C REDUCTASE;

BINDING SITE; BIOENERGY; CHEMICAL REACTION; DISSOCIATION CONSTANT; ELECTRON; ELECTRON TRANSPORT; ENTHALPY; ENZYME ACTIVITY; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STABILITY; PROTON TRANSPORT; REVIEW; SHORT CIRCUIT CURRENT;

EID: 16244377712     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tibs.2005.02.001     Document Type: Article

References (50)

1. 1 complex in the respiratory chain: protonmotive ubiquinone cycle FEBS Lett. 56 1975 1 6
2. P. Mitchell The protonmotive Q cycle: a general formulation FEBS Lett. 59 1975 137 139
3. P. Mitchell Possible molecular mechanisms of the protonmotive function of cytochrome systems J. Theor. Biol. 62 1976 327 367
4. D.G. Nicholls, and S.J. Ferguson Bioenergetics 3rd edn 2002 Academic Press
5. P.L. Dutton Coenzyme Q oxidation reduction reactions in mitochondrial elecron transport V.E. Kagan P.J. Quinn Coenzyme Q: Molecular Mechanisms in Health and Disease 2000 CRC Press 65 82
6. E.A. Berry Structure and function of cytochrome bc complexes Annu. Rev. Biochem. 69 2000 1005 1075
7. 1: a new device for electron transfer in proteins Trends Biochem. Sci. 26 2001 445 451
8. 6f: structure for signalling and vectorial metabolism Trends Plant Sci. 9 2004 130 137
9. 6f complex: similarities and differences Photosynth. Res. 79 2004 25 44
10. 1 complex from bovine heart mitochondria Science 277 1997 60 66
11. 1 complex Science 281 1998 64 71
12. 1 Nature 392 1998 677 684
13. v fragment Structure 8 2000 669 684
14. 1: comparison with its mitochondrial and chloroplast counterparts Photosynth. Res. 81 2004 251 275
15. 6f complex Nature 426 2003 413 418
16. 6f complex of oxygenic photosynthesis: tuning the cavity Science 302 2003 1009 1014
17. C.C. Moser Nature of biological electron transfer Nature 355 1992 796 802
18. C.C. Page Natural engineering principles of electron tunneling in biological oxidation-reduction Nature 402 1999 47 52
19. 1 complex from bovine heart Proc. Natl. Acad. Sci. U. S. A. 95 1998 8026 8033
20. o site model Biochemistry 31 1992 3144 3158
21. 1 complex Biochemistry 34 1995 15979 15996
22. o site inhibitor Biochemistry 38 1999 3440 3446
23. 1 complex Biochemistry 38 1999 14973 14980
24. 1 complex J. Biol. Chem. 276 2001 35231 35234
25. 1 complex FEBS Lett. 555 2003 13 20
26. 1 complex J. Mol. Biol. 341 2004 281 302
27. 2) oxidoreductase of respiratory and photosynthetic systems J. Biol. Chem. 259 1984 1758 1763
28. B. Chance, and G. Hollunger The interaction of energy and electron transfer reactions in mitochondria J. Biol. Chem. 236 1961 1562 1568
29. A. Osyczka Reversible redox energy coupling in electron transfer chains Nature 427 2004 607 612
30. o center Eur. J. Biochem. 195 1991 163 170
31. 1 complex Biochim. Biophys. Acta 1365 1998 261 268
32. 1 complex Proc. Natl. Acad. Sci. U. S. A. 96 1999 10021 10026
33. 1 complex: different domains of the quinol binding pocket and their role in the mechanism and binding of inhibitors Biochemistry 38 1999 15807 15826
34. 1 complex Biochim. Biophys. Acta 1555 2002 65 70
35. 1 and the voltage generation Biochim. Biophys. Acta 1553 2002 177 182
36. 1 complex. The 'proton-gated affinity change' mechanism FEBS Lett. 412 1997 257 264
37. 1 complex J. Biol. Chem. 275 2000 13535 13541
38. 1 complex by proton-gated charge transfer FEBS Lett. 387 1996 1 6
39. M. Wikstrom Water-gated mechanism of proton translocation by cytochrome c oxidase Biochim. Biophys. Acta 1604 2003 61 65
40. P.R. Rich The quinone chemistry of bc complexes Biochim. Biophys. Acta 1658 2004 165 171
41. 1 complex Biochim. Biophys. Acta 1555 2002 166 173
42. 1 complex of Rhodobacter capsulatus probed by site-directed mutagenesis Biochemistry 31 1992 3342 3351
43. 1 complex FEBS Lett. 545 2003 39 46
44. 6f turnover Biochemistry 37 1998 10395 10403
45. 3 from Rhodobacter sphaeroides is involved in proton uptake during the reaction of the fully-reduced enzyme with dioxygen Biochemistry 36 1997 13824 13829
46. P. Brzezinski Redox-driven membrane-bound proton pumps Trends Biochem. Sci. 29 2004 380 387
47. K-I. Takamiya, and P.L. Dutton Ubiquinone in Rhodopseudomonas sphaeroides some thermodynamic properties Biochim. Biophys. Acta 546 1979 1 16
48. 1 complex J. Biol. Chem. 273 1998 21603 21607
49. W.P. Jencks Binding energy, specificity, and enzymatic catalysis: the Circe effect Adv. Enzymol. 43 1975 219 410
50. Cornish-Bowen, A. (1995) The reversible Michaelis-Menton mechanism. In Fundamentals of Enzyme Kinetics, pp. 37-43, Portland Press