Deleted in polyposis 1-like 1 gene (Dp1l1): A novel gene richly expressed in retinal ganglion cells

Investigative Ophthalmology and Visual Science

Volumn 46, Issue 3, 2005, Pages 791-796

  Sato, Hajime ^a   Tomita, Hiroshi ^a   Nakazawa, Toru ^a   Wakana, Shigeharu ^b   Tamai, Makoto ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b RIKEN YOKOHAMA INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; DELETED IN POLYPOSIS 1 LIKE 1 PROTEIN; GENE PRODUCT; MEMBRANE PROTEIN; UNCLASSIFIED DRUG; DELETED IN POLYPOSIS 1 LIKE 1 GENE PROTEIN, MOUSE; DELETED IN POLYPOSIS 1 LIKE 1 GENE PROTEIN, RAT; DELETED IN POLYPOSIS 1-LIKE 1 GENE PROTEIN, MOUSE; DELETED IN POLYPOSIS 1-LIKE 1 GENE PROTEIN, RAT; EYE PROTEIN; MESSENGER RNA;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; BIOINFORMATICS; BRAIN; CELL MEMBRANE TRANSPORT; CHROMOSOME 10; CYTOPLASM; DELETED IN POLYPOSIS 1 LIKE 1 GENE; GENE; GENE EXPRESSION; GENE LOCATION; GENE MAPPING; GENE SEQUENCE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INTRACELLULAR MEMBRANE; MOUSE; MOUSE STRAIN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; RADIATION HYBRID MAPPING; RAT; RAT STRAIN; RETINA; RETINA GANGLION CELL; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; ANIMAL; C57BL MOUSE; CHEMICAL STRUCTURE; COMPARATIVE STUDY; GENE LIBRARY; GENETICS; HUMAN; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; MOLECULAR GENETICS; NORTHERN BLOTTING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BLOTTING, NORTHERN; BLOTTING, WESTERN; EYE PROTEINS; GENE EXPRESSION; GENE LIBRARY; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MICE; MICE, INBRED C57BL; MICE, INBRED ICR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; RADIATION HYBRID MAPPING; RATS; RATS, SPRAGUE-DAWLEY; RETINAL GANGLION CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 16244369132     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.04-0867     Document Type: Article

References (21)

1. Xiang M, Zhou H, Nathans J. Molecular biology of retinal ganglion cells. Proc Natl Acad Sci USA. 1996;93:596-601.
2. Alexander C, Votruba M, Pesch UE, et al. OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28. Nat Genet. 2000;26:211-215.
3. Delettre C, Lenaers G, Griffoin JM, et al. Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy. Nat Genet. 2000;26:207-210.
4. Pesch UE, Fries JE, Bette S, et al. OPA1, the disease gene for autosomal dominant optic atrophy is specifically expressed in ganglion cells and intrinsic neurons of the retina. Invest Ophthalmol Vis Sci. 2004;45:4217-4225.
5. Nickells RW. Retinal ganglion cell death in glaucoma: the how, the why, and the maybe. J Glaucoma. 1996;5:345-356.
6. Tezel G, Yang J, Wax MB. Heat shock proteins, immunity and glaucoma. Brain Res Bull. 2004;62:473-480.
7. Levin LA. Direct and indirect approaches to neuroprotective therapy of glaucomatous optic neuropathy. Surv Ophthalmol. 1999; 43(suppl 1):S98-S101.
8. Levin LA. Intrinsic survival mechanisms for retinal ganglion cells. Eur J Ophthalmol. 1999;9(suppl 1):S12-S16.
9. Kanekolshino T, Kuroiwa Y, Miyoshi N, et al. Pegl/Mest imprinted gene on chromosome 6 identified by cDNA subtraction hybridization. Nat Genet. 1995;11:52-59.
10. Sato H, Koide T, Sagai T, et al. The genomic organization of type I keratin genes in mice. Genomics. 1999;56:303-309.
11. He L, Poblenz AT, Medrano CJ, Fox DA. Lead and calcium produce rod photoreceptor cell apoptosis by opening the mitochondrial permeability transition pore. J Biol Chem. 2000;275:12175-12184.
12. Nakazawa T, Tamai M, Mori N. Brain-derived neurotrophic factor prevents axotomized retinal ganglion cell death through MAPK and PI3K signaling pathways. Invest Ophthalmol Vis Sci. 2002;43: 3319-3326.
13. Kozak M. Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. Cell. 1986;44:283-292.
14. Kozak M. At least six nucleotides preceding the AUG initiator codon enhance translation in mammalian cells. J Mol Biol. 1987; 196:947-950.
15. Joslyn G, Carlson M, Thliveris A, et al. Identification of deletion mutations and three new genes at the familial polyposis locus. Cell. 1991;66:601-613.
16. Kinzler KW, Nilbert MC, Su LK, et al. Identification of FAP locus genes from chromosome 5q21. Science. 1991;253:66l-665.
17. Prieschl EE, Pendl GG, Harrer NE, Baumruker T. The mutine homolog of TB2/DP1, a gene of the familial adenomatous polyposis (FAP) locus. Gene. 1996;169:215-218.
18. Calero M, Whittaker GR, Collins RN. Yop1p, the yeast homolog of the polyposis locus protein 1, interacts with Yip1p and negatively regulates cell growth. J Biol Chem. 2001;276:12100-12112.
19. Brands A, Ho TH. Function of a plant stress-induced gene, HVA22. Synthetic enhancement screen with its yeast homolog reveals its role in vesicular traffic. Plant Physiol. 2002;130:1121-1131.
20. Mulugeta S, Ciavarra RP, Maney RK, Tedeschi B. Three subpopulations of fast axonally transported retinal ganglion cell proteins are differentially trafficked in the rat optic pathway. J Neurosci Res. 2000;59:247-258.
21. Wiggs JL, Allingham RR, Hossain A, et al. Genome-wide scan for adult onset primary open angle glaucoma. Hum Mol Genet. 2000; 9:1109-1117.