Intrinsic survival mechanisms for retinal ganglion cells

European Journal of Ophthalmology

Volumn 9, Issue SUPPL. 1, 1999, Pages

  Levin, L A ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Apoptosis; Neuroprotection; Retinal ganglion cells

Indexed keywords

NEUROTROPHIC FACTOR; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; CELL DEATH; CELL SURVIVAL; GENE EXPRESSION REGULATION; GLYCOLYSIS; HYPOXIA; NERVE FIBER TRANSECTION; NERVE INJURY; NEUROPROTECTION; NONHUMAN; OPTIC NERVE; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION; RETINA GANGLION CELL; RETROGRADE NERVE FIBER TRANSPORT; REVIEW;

EID: 0032904535     PISSN: 11206721     EISSN: None     Source Type: Journal    
DOI: 10.1177/112067219900901s08     Document Type: Review

References (45)

1. Mansour-Robaey S, Clarke D, Wang YC, Bray G M, Aguayo AJ. Effects of ocular injury and administration of brain-derived neurotrophic factor on survival and regrowth of axotomized retinal ganglion cells. Proc Natl Acad Sci USA 1994; 91: 1632-6.
2. Yoles E, Muller S, Schwartz M. NMDA-receptor antagonist protects neurons from secondary degeneration after partial optic nerve crush. J Neurotrauma 1997; 14: 665-75.
3. Berkelaar M, Clarke DB, Wang YC, Bray GM, Aguayo AJ. Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats. J Neurosci 1994; 14: 4368-74.
4. Garcia-Valenzuela E, Gorczyca W, Darzynkiewicz Z, Sharma SC. Apoptosis in adult retinal ganglion cells after axotomy. J Neurobiol 1994; 25: 431-8.
5. Rehen SK, Linden R. Apoptosis in the developing retina: paradoxical effects of protein synthesis inhibition. Braz J Med Biol Res 1994; 27: 1647-51.
6. Quigley HA et al. Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis. Invest Ophthalmol Vis Sci 1995; 36: 774-86.
7. Levin LA, Louhab A. Apoptosis of retinal ganglion cells in anterior ischemic optic neuropathy. Arch Ophthalmol 1996; 114: 488-91.
8. Levin LA, Schlamp CL, Spieldoch RL, Geszvain KM, Nickells RW. Identification of bcl-2 family genes in the rat retina. Invest Ophthalmol Vis Sci 1997; 38.
9. Levin, LA, Geszvain KM. Expression of ceruloplasmin in the retina: Induction after retinal ganglion cell axotomy. Invest Ophthalmol Vis Sci 1998; 39: 157-63.
10. Levin LA, Johns LK. Hypoxia inhibits death of retinal ganglion cells in mixed culture. Invest Ophthalmol Vis Sci 1997; 38 (suppl): S6.
11. Levin LA, Clark JA, Johns, LK. Effect of lipid peroxidation inhibition on retinal ganglion cell death. Invest Ophthalmol Vis Sci 1996; 37: 2744-9.
12. Cragg BG. What is the signal for chromatolysis? Brain Res 1970; 23: 1-21.
13. Thanos S, Pavlidis C, Mey J, Thiel HJ. Specific transcellular staining of microglia in the adult rat after traumatic degeneration of carbocyanine-filled retinal ganglion cells. Exp Eye Res 1992; 55: 101-17.
14. Watson WE. Cellular responses to axotomy and to related procedures. Br Med Bull 1974; 30: 112-5.
15. Grafstein B, Ingoglia NA. Intracranial transection of the optic nerve in adult mice: Preliminary observations. Exp Neurol 1982; 76: 318-30.
16. Schnitzer J, Scherer J. Microglial cell responses in the rabbit retina following transection of the optic nerve. J Comp Neurol 1990; 302: 779-91.
17. Cui Q, Harvey AR. At least two mechanisms are involved in the death of retinal ganglion cells following target ablation in neonatal rats. J Neurosci 1995; 15: 8143-55.
18. Aguayo AJ et al. Effects of neurotrophins on the survival and regrowth of injured retinal neurons. Ciba Foundation Symp 1996; 196: 135-44.
19. Mey J, Thanos S. Intravitreal injections of neurotrophic factors support the survival of axotomized retinal ganglion cells in adult rats in vivo. Brain Res 1993; 602: 304-17.
20. Maffei L, Carmignoto G, Perry VH, Candeo P, Ferrari G. Schwann cells promote the survival of rat retinal ganglion cells after optic nerve section. Proc Natl Acad Sci USA 1990; 87: 1855-9.
21. Castillo BJ et al. Retinal ganglion cell survival is promoted by genetically modified astrocytes designed to secrete brain-derived neurotrophic factor (BDNF). Brain Res 1994; 647: 30-6.
22. Weibel D, Kreutzberg GW, Schwab ME. Brain-derived neurotrophic factor (BDNF) prevents lesion-induced axonal die-back in young rat optic nerve. Brain Res 1995; 679: 249-54.
23. Peinado-Ramon P, Salvador M, Villegas-Perez MP, Vidal-Sanz M. Effects of axotomy and intraocular administration of NT-4, NT-3, and brain-derived neurotrophic factor on the survival of adult rat retinal ganglion cells. A quantitative in vivo study. Invest Ophthalmol Vis Sci 1996; 7: 489-500.
24. Meyer-Franke A, Kaplan MR, Pfrieger FW, Barres BA. Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture. Neuron 1995; 15: 805-19.
25. Kane DJ, SarafianTA et al. Bcl-2 inhibition of neural death: Decreased generation of reactive oxygen species. Science 1993; 262: 1274-7.
26. Hockenbery DM, Oltvai ZN, Yin XM, Milliman CL, Korsmeyer SJ. BCL-2 functions in an antioxidant pathway to prevent apoptosis. Cell 1993; 75: 241-51.
27. Tappel AL. Lipid peroxidation damage to cell components. Fed Proc 1973; 32: 1870-4.
28. Murray M, Grafstein B. Changes in the morphology and amino acid incorporation of regenerating goldfish optic neurons. Exp Neurol 1969; 23: 544-60.
29. Humphrey MF, Beazley LD. Retinal ganglion cell death during optic nerve regeneration in the frog Hyla moorei. J Comp Neurol 1985; 263: 382-402.
30. Humphrey MF. A morphometric study of the retinal ganglion cell response to optic nerve severance in the frog Rana pipiens. J Neurocytol 1988; 17: 293-304.
31. Allcutt D, Berry M, Sievers J. A qualitative comparison of the reactions of retinal ganglion cell axons to optic nerve crush in neonatal and adult mice. Brain Res 1984; 318: 231-40.
32. Allcutt D, Berry M, Sievers J. A quantitative comparison of the reactions of retinal ganglion cells to optic nerve crush in neonatal and adult mice. Brain Res 1984; 318: 219-30.
33. Barron KD, Dentinger MP, Krohel G, Easton SK, Mankes R. Qualitative and quantitative ultrastructural observations on retinal ganglion cell layer of rat after intraorbital optic nerve crush. J Neurocytol 1986; 15: 345-62.
34. Misantone LJ, Gershenbaum M, Murray M. Viability of retinal ganglion cells after optic nerve crush in adult rats. J Neurocytol 1984; 13: 449-65.
35. Villegas-Perez MP, Vidal-Sanz M, Rasminsky M, Bray GM, Aguayo AJ. Rapid and protracted phases of retinal ganglion cell loss follow axotomy in the optic nerve of adult rats. J Neurobiol 1993; 24: 23-36.
36. Radius RL, Anderson DR. Retinal ganglion cell degeneration in experimental optic atrophy. Am J Ophthalmol 1978; 86: 673-9.
37. Quigley HA, Anderson DR. Descending optic nerve degeneration in primates. Invest Ophthalmol Vis Sci 1977; 16: 841-9.
38. Kupfer C. Retinal ganglion cell degeneration following chiasmal lesions in man. Arch Ophthalmol 1963; 70: 256-60.
39. Liang P, Pardee AB. Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science 1992; 257: 967-71.
40. Gutteridge JM. Inhibition of the Fenton reaction by the protein caeruloplasmin and other copper complexes. Assessment of ferroxidase and radical scavenging activities. Chem Biol Interact 1985; 6: 113-20.
41. Al Timimi DJ, Dormandy TL. The inhibition of lipid autoxidation by human caeruloplasmin. Biochem J 1977; 68: 283-8.
42. Gutteridge JM. Antioxidant properties of caeruloplasmin towards iron- and copper-dependent oxygen radical formation. FEBS Lett 1983; 157: 37-40.
43. Loeffler DA et al. Ceruloplasmin is increased in cerebrospinal fluid in Alzheimer's disease but not Parkinson's disease. Alzheim Dis Assoc Disord 1994; 8: 190-7.
44. Loeffler DA et al. Increased regional brain concentrations of ceruloplasmin in neurodegenerative disorders. Brain Res 1996; 738; 265-74.
45. Jacobson MD, Raff MC. Programmed cell death and Bcl-2 protection in very low oxygen. Nature 1995; 374: 814-6.