Mast cell degranulation induced by two phospholipase A2 homologues: Dissociation between enzymatic and biological activities

European Journal of Pharmacology

Volumn 343, Issue 2-3, 1998, Pages 257-263

  Landucci, Elen C T ^a   Castro, Rogerio C ^a   Pereira, Maristela F ^a   Cintra, Adelia C O ^b   Giglio, Jose R ^b   Marangoni, Sergio ^a   Oliveira, Benedito ^a   Cirino, Giuseppe ^c   Antunes, Edson ^a   De Nucci, Gilberto ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c Department Experimental Pharmacology   (Italy)

Author keywords

Bothropstoxin; Inflammation; Mast cell degranulation; Phospholipase A2; Snake venom

Indexed keywords

ALBUMIN I 125; BOTHROPSTOXIN 1; BOTHROPSTOXIN 2; COMPOUND 48-80; CYPROHEPTADINE; HEPARIN; PHOSPHOLIPASE A2; SEROTONIN; SNAKE VENOM; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVITY; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MAST CELL DEGRANULATION; NONHUMAN; PAW EDEMA; PRIORITY JOURNAL; PROTEIN MODIFICATION; RAT; SEROTONIN RELEASE; SKIN EDEMA;

ANIMALS; CELL DEGRANULATION; CROTALID VENOMS; EDEMA; MALE; MAST CELLS; PHOSPHOLIPASES A; RATS; RATS, WISTAR; SKIN;

EID: 0032545928     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)01546-X     Document Type: Article

References (36)

1. Antunes E., Mariano M., Cirino G., Levi S., De Nucci G. Pharmacological characterisation of polycation-induced rat hind-paw oedema. Br. J. Pharmacol. 101:1990;986-990.
2. Barker R.L., Gundel R.H., Gleich G.J., Checkel J.L., Loegering D.A., Pease L.R., Hamann K.J. Acid polyamino acids inhibit human eosinophil granule major basic protein toxicity. J. Clin. Invest. 88:1991;798-805.
3. Blackwell G.J., Flower R.J. Inhibition of phospholipase. Br. Med. Bull. 39:1983;260-264.
4. Brain S.D., Williams T.J. Inflammatory oedema induced by synergism between calcitonin gene-related peptide (CGRP) and mediators of increased vascular permeability. Br. J. Pharmacol. 86:1985;855-860.
5. Cintra A.C.O., Marangoni S., Oliveira B., Giglio J.R. Bothropstoxin-I: Amino acid sequence and function. J. Protein Chem. 12:1993;57-64.
6. 2-induced oedema in rat paw. Eur. J. Pharmacol. 166:1989;505-510.
7. Coleman J.W., Holgate S.T., Church M.K., Godfrey R.C. Immunoglobulin E decapeptide-induced 5-hydroxytryptamine release from rat peritoneal mast cells. Biochem. J. 198:1981;615-619.
8. Dennis E.A. Regulation of eicosanoid production: Role of phospholipase and inhibitors. BioTechnology. 5:1987;1294-1300.
9. 2, affects its pharmacological activities. Toxicon. 31:1993;1202-1206.
10. Ennis M., Pearce F.L., Weston P.M. Some studies on the release of histamine from mast cells stimulated with polylysine. Br. J. Pharmacol. 70:1980;329-334.
11. Fredens K., Dahl R., Venge P. In vitro studies of the interaction between heparin and eosinophil cationic protein. Allergy. 46:1991;27-29.
12. 2 myotoxins from Bothrops snake venoms. Toxicon. 33:1995;1405-1424.
13. Homsi-Brandeburgo M.l., Queiroz L.S., Santo-Neto H., RodriguesSimioni L., Giglio J.R. Fractionation of Bothrops jararacussu snake venom: Partial chemical characterization and biological activity of bothropstoxin. Toxicon. 26:1988;615-627.
14. Ichimura S., Zama M. The interactions of 8-anilinonaphtalenesulfonate with polylysine and polyarginine. Biopolymers. 16:1977;1449-1464.
15. Ichimura S., Mita K., Zama M. Conformation of poly (L-arginine). I. Effects of anions. Biopolymers. 17:1978;2769-2782.
16. 2. Toxicon. 27:1989;613-635.
17. Lane, D.A., Lindahl, U., 1989. Heparin: Chemical and Biological Properties, Clinical Application, Edward Arnold, London.
18. 2 purified from porcine pancreas and snake venoms. Toxicon. 31:1993;949-956.
19. 2, eicosanoid release and cellular accumulation in rat immunological air pouch inflammation. Int. J. Immunopharmacol. 15:1993;597-603.
20. 2-induced oedema in rat skin and histamine release in rat mast cells. Evidence for involvement of Iysophospholipids in the mechanism of action. Agents Actions. 36:1992;258-263.
21. 2. J. Immunol. 151:1993;5675-5684.
22. Needham L., Hellewell P.G., Williams T.J., Gordon J.L. Endothelial functional responses and increased vascular permeability induced by polycations. Lab. Invest. 59:1988;538-548.
23. Padawer J. The reaction of rat mast cells to polylysine. J. Cell Biol. 47:1970;352-372.
24. 2 correlates with disease activity in rheumatoid arthritis. J. Rheumat. 15:1988;1351-1356.
25. 2 myotoxin. Toxicon. 33:1995;1479-1489.
26. 2 by modification of carboxylate groups. Biochem. Pharmacol. 32:1983;3525-3530.
27. Santana A., Hyslop S., Antunes E., Mariano M., Bakhle Y.S., De Nucci G. Inflammatory responses induced by poly-L-arginine in rats lungs in vivo. Agents Actions. 39:1993;104-110.
28. 2 type II to proteoglycans: Differential effect of glycosaminoglycans on enzyme activity. J. Biol. Chem. 271:1996;26307-26314.
29. 2 in human acute pancreatitis. Scand. J. Gastroenterol. 15:1980;633-636.
30. Schwartz L.B. Mast cells: Function and contents. Curr. Opin. Immunol. 6:1994;91-97.
31. 2 levels correlation with the hemodynamic and pulmonary changes in Gram-negative septic shock. J. Lab. Clin. Med. 104:1984;873-877.
32. 2 in the pathogenesis of the hemodynamic changes in endotoxin shock. Can. J. Physiol. Pharmacol. 61:1983;561-567.
33. 2 and their importance for enzymatic activity. J. Cell. Biochem. 39:1988;379-390.
34. Waite, M., 1987. The phospholipases. In: Hanahan, D.J. (Ed.), Handbook of Lipid Research, vol. 5. Plenum Press, New York, p. 155.
35. 2 enzymes. Eur. J. Pharmacol. 190:1990;347-354.
36. 2 from snake venoms. J. Toxicol. 13:1994;125-177.