The apolipoprotein CI content of triglyceride-rich lipoproteins independently predicts early atherosclerosis in healthy middle-aged men

Journal of the American College of Cardiology

Volumn 45, Issue 7, 2005, Pages 1013-1017

  Hamsten, Anders ^a   Silveira, Angela ^a   Boquist, Susanna ^b   Tang, Rong ^c   Bond, M Gene ^c   De Faire, Ulf ^a   Björkegren, Johan ^a,b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B100; APOLIPOPROTEIN C1; APOLIPOPROTEIN E3; FAT; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PROINSULIN; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ADULT; ARTERY INTIMA PROLIFERATION; ARTICLE; ATHEROSCLEROSIS; BODY DENSITY; BODY FAT; CHOLESTEROL BLOOD LEVEL; CLEARANCE; CLINICAL EXAMINATION; COMMON CAROTID ARTERY; CONTROLLED STUDY; CORONARY RISK; CORRELATION ANALYSIS; DISEASE ASSOCIATION; GENOTYPE; HEAT STRESS; HUMAN; INSULIN BLOOD LEVEL; ISCHEMIC HEART DISEASE; LIPOPROTEIN BLOOD LEVEL; LIPOPROTEIN METABOLISM; LOADING TEST; MALE; MULTIVARIATE ANALYSIS; NORMAL HUMAN; POSTPRANDIAL STATE; PREDICTION; PRIORITY JOURNAL; PROTEIN CONTENT; SOCIETY; TRIACYLGLYCEROL BLOOD LEVEL; ULTRASOUND; VASCULARIZATION;

EID: 15944409983     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2004.12.049     Document Type: Article

References (32)

1. F. Karpe Postprandial lipoprotein metabolism and atherosclerosis J Intern Med 246 1999 341 355
2. L.A. Simons, T. Dwyer, J. Simons Chylomicrons and chylomicron remnants in coronary artery disease: a case-control study Atherosclerosis 65 1987 181 189
3. F. Karpe, G. Steiner, K. Uffelman, T. Olivecrona, A. Hamsten Postprandial lipoproteins and progression of coronary atherosclerosis Atherosclerosis 106 1994 83 97
4. M.S. Weintraub, I. Grosskopf, T. Rassin Clearance of chylomicron remnants in normolipidaemic patients with coronary artery disease: case control study over three years BMJ 312 1996 936 939
5. F. Karpe, U. de Faire, M. Mercuri, M.G. Bond, M.L. Hellenius, A. Hamsten Magnitude of alimentary lipemia is related to intima-media thickness of the common carotid artery in middle-aged men Atherosclerosis 141 1998 307 314
6. I.J. Goldberg, J.J. Kandel, C.B. Blum, H.N. Ginsberg Association of plasma lipoproteins with postheparin lipase activities J Clin Invest 78 1986 1523 1528
7. A.D. Cooper Hepatic uptake of chylomicron remnants J Lipid Res 38 1997 2173 2192
8. F. Karpe, G. Steiner, T. Olivecrona, L.A. Carlson, A. Hamsten Metabolism of triglyceride-rich lipoproteins during alimentary lipemia J Clin Invest 91 1993 748 758
9. J. Bjorkegren, C.J. Packard, A. Hamsten Accumulation of large very low density lipoprotein in plasma during intravenous infusion of a chylomicron-like triglyceride emulsion reflects competition for a common lipolytic pathway J Lipid Res 37 1996 76 86
10. R.W. Mahley Apolipoprotein E: cholesterol transport protein with expanding role in cell biology Science 240 1988 622 630
11. M.C. Jong, M.H. Hofker, L.M. Havekes Role of ApoCs in lipoprotein metabolism: functional differences between ApoC1, ApoC2, and ApoC3 Arterioscler Thromb Vasc Biol 19 1999 472 484
12. J.C. LaRosa, R.I. Levy, P. Herbert, S.E. Lux, D.S. Fredrickson A specific apoprotein activator for lipoprotein lipase Biochem Biophys Res Commun 41 1970 57 62
13. C.S. Wang, W.J. McConathy, H.U. Kloer, P. Alaupovic Modulation of lipoprotein lipase activity by apolipoproteins Effect of apolipoprotein C-III J Clin Invest 75 1985 384 390
14. N.S. Shachter, T. Ebara, R. Ramakrishnan Combined hyperlipidemia in transgenic mice overexpressing human apolipoprotein CI J Clin Invest 98 1996 846 855
15. J. Bjorkegren, A. Hamsten, R.W. Milne, F. Karpe Alterations of VLDL composition during alimentary lipemia J Lipid Res 38 1997 301 314
16. J. Bjorkegren, F. Karpe, R.W. Milne, A. Hamsten Differences in apolipoprotein and lipid composition between human chylomicron remnants and very low density lipoproteins isolated from fasting and postprandial plasma J Lipid Res 39 1998 1412 1420
17. J. Bjorkegren, S. Boquist, A. Samnegard Accumulation of apolipoprotein C-I-rich and cholesterol-rich VLDL remnants during exaggerated postprandial triglyceridemia in normolipidemic patients with coronary artery disease Circulation 101 2000 227 230
18. J. Bjorkegren, A. Silveira, S. Boquist Postprandial enrichment of remnant lipoproteins with apoC-I in healthy normolipidemic men with early asymptomatic atherosclerosis Arterioscler Thromb Vasc Biol 22 2002 1470 1474
19. F. Karpe, A. Hamsten Determination of apolipoproteins B-48 and B-100 in triglyceride-rich lipoproteins by analytical SDS-PAGE J Lipid Res 35 1994 1311 1317
20. K. Carlsson Lipoprotein fractionation J Clin Pathol 26 1973 32 37
21. L. Holmquist Quantitation of human serum very low density apolipoproteins C-I, C-II, C-III and E by enzyme immunoassay J Immunol Methods 34 1980 243 251
22. A.M. van den Maagdenberg, P. de Knijff, A.F. Stalenhoef, J.A. Gevers Leuven, L.M. Havekes, R.R. Frants Apolipoprotein E*3-Leiden allele results from a partial gene duplication in exon 4 Biochem Biophys Res Commun 165 1989 851 857
23. M. Mercuri, R. Tang, R.M. Phillips, M.G. Bond Ultrasound protocol and quality control procedures in the European Lacidipine Study on Atherosclerosis (ELSA) Blood Press Suppl 4 1996 20 23
24. M. Wong, J. Edelstein, J. Wollman, M.G. Bond Ultrasonic-pathological comparison of the human arterial wall Verification of intima-media thickness Arterioscler Thromb 13 1993 482 486
25. G. Heiss, A.R. Sharrett, R. Barnes, L.E. Chambless, M. Szklo, C. Alzola Carotid atherosclerosis measured by B-mode ultrasound in populations: associations with cardiovascular risk factors in the ARIC study Am J Epidemiol 134 1991 250 256
26. T.E. Craven, J.E. Ryu, M.A. Espeland Evaluation of the associations between carotid artery atherosclerosis and coronary artery stenosis A case-control study Circulation 82 1990 1230 1242
27. J.L. Wofford, F.R. Kahl, G.R. Howard, W.M. McKinney, J.F. Toole, J.R. Crouse 3rd Relation of extent of extracranial carotid artery atherosclerosis as measured by B-mode ultrasound to the extent of coronary atherosclerosis Arterioscler Thromb 11 1991 1786 1794
28. L.E. Chambless, G. Heiss, A.R. Folsom Association of coronary heart disease incidence with carotid arterial wall thickness and major risk factors: the Atherosclerosis Risk in Communities (ARIC) study, 1987-1993 Am J Epidemiol 146 1997 483 494
29. J.G. Terry, G. Howard, M. Mercuri, M.G. Bond, J.R. Crouse 3rd Apolipoprotein E polymorphism is associated with segment-specific extracranial carotid artery intima-media thickening Stroke 27 1996 1755 1759
30. L. Cattin, M. Fisicaro, M. Tonizzo Polymorphism of the apolipoprotein E gene and early carotid atherosclerosis defined by ultrasonography in asymptomatic adults Arterioscler Thromb Vasc Biol 17 1997 91 94
31. S. Boquist, G. Ruotolo, R. Tang Alimentary lipemia, postprandial triglyceride-rich lipoproteins, and common carotid intima-media thickness in healthy, middle-aged men Circulation 100 1999 723 728
32. R.J. Havel, J.P. Kane, M.L. Kashyap Interchange of apolipoproteins between chylomicrons and high density lipoproteins during alimentary lipemia in man J Clin Invest 52 1973 32 38