Molecular cloning and characterization of two novel truncated isoforms of human Na+/Ca2+ exchanger 3, expressed in fetal brain

Gene

Volumn 348, Issue 1-2 SUPPL., 2005, Pages 143-155

  Lindgren, Rose Marie ^a   Zhao, Jian ^b   Heller, Susanne ^a   Berglind, Hanna ^b   Nistér, Monica ^b  

^a UPPSALA UNIVERSITY   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Alternative splicing; CNS; NCX3; SLC8A3

Indexed keywords

AMINO ACID; CALCIUM ION; POLYPEPTIDE; SODIUM CALCIUM EXCHANGE PROTEIN; SODIUM ION;

AMINO TERMINAL SEQUENCE; ARTICLE; BIOINFORMATICS; BRAIN; CODON; EXON; FETUS; GENE IDENTIFICATION; GENETIC CODE; GENETIC TRANSCRIPTION; HOMEOSTASIS AND REGULATION; HUMAN; HUMAN CELL; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STRUCTURE; RNA SPLICING; SEQUENCE ANALYSIS; UNTRANSLATED REGION;

EID: 15744364875     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2005.01.003     Document Type: Article

References (32)

1. K.V. Barnes, G. Cheng, M.M. Dawson, and D.R. Menick Cloning of cardiac, kidney, and brain promoters of the feline ncx1 gene J. Biol. Chem. 272 1997 11510 11517
2. P. Chomczynski, and N. Sacchi Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction Anal. Biochem. 162 1987 156 159
3. I. Furman, O. Cook, J. Kasir, and H. Rahamimoff Cloning of two isoforms of the rat brain Na(+)-Ca2+ exchanger gene and their functional expression in HeLa cells FEBS Lett. 319 1993 105 109
4. N. Gabellini, T. Iwata, and E. Carafoli An alternative splicing site modifies the carboxyl-terminal trans-membrane domains of the Na+/Ca2+ exchanger J. Biol. Chem. 270 1995 6917 6924
5. N. Gabellini, A. Zatti, G. Rispoli, A. Navangione, and E. Carafoli Expression of an active Na+/Ca2+ exchanger isoform lacking the six C-terminal transmembrane segments Eur. J. Biochem. 239 1996 897 904
6. N. Gabellini, S. Bortoluzzi, G.A. Danieli, and E. Carafoli The human SLC8A3 gene and the tissue-specific Na+/Ca2+ exchanger 3 isoforms Gene 298 2002 1 7
7. R. Kikuno Prediction of the coding sequences of unidentified human genes: XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro DNA Res. 6 1999 197 205
8. P. Kofuji, W.J. Lederer, and D.H. Schulze Mutually exclusive and cassette exons underlie alternatively spliced isoforms of the Na/Ca exchanger J. Biol. Chem. 269 1994 5145 5149
9. M. Kozak Pushing the limits of the scanning mechanism for initiation of translation Gene 299 2002 1 34
10. A. Kraev, I. Chumakov, and E. Carafoli The organization of the human gene NCX1 encoding the sodium-calcium exchanger Genomics 37 1996 105 112
11. S.L. Lee, A.S. Yu, and J. Lytton Tissue-specific expression of Na(+)-Ca2+ exchanger isoforms J. Biol. Chem. 269 1994 14849 14852
12. X.F. Li, and J. Lytton A circularized sodium-calcium exchanger exon 2 transcript J. Biol. Chem. 274 1999 8153 8160
13. Z. Li Identification of a peptide inhibitor of the cardiac sarcolemmal Na(+)-Ca2+ exchanger J. Biol. Chem. 266 1991 1014 1020
14. Z. Li Cloning of the NCX2 isoform of the plasma membrane Na(+)-Ca2+ exchanger J. Biol. Chem. 269 1994 17434 17439
15. S. Matsuoka, D.A. Nicoll, Z. He, and K.D. Philipson Regulation of cardiac Na(+)-Ca2+ exchanger by the endogenous XIP region J. Gen. Physiol. 109 1997 273 286
16. S.M. Mount A catalogue of splice junction sequences Nucleic Acids Res. 10 1982 459 472
17. S.B. Nicholas, W. Yang, S.L. Lee, H. Zhu, K.D. Philipson, and J. Lytton Alternative promoters and cardiac muscle cell-specific expression of the Na+/Ca2+ exchanger gene Am. J. Physiol. 274 1998 H217 H232
18. D.A. Nicoll, S. Longoni, and K.D. Philipson Molecular cloning and functional expression of the cardiac sarcolemmal Na(+)-Ca2+ exchanger Science 250 1990 562 565
19. D.A. Nicoll, L.V. Hryshko, S. Matsuoka, J.S. Frank, and K.D. Philipson Mutation of amino acid residues in the putative transmembrane segments of the cardiac sarcolemmal Na+-Ca2+ exchanger J. Biol. Chem. 271 1996 13385 13391
20. D.A. Nicoll, B.D. Quednau, Z. Qui, Y.R. Xia, A.J. Lusis, and K.D. Philipson Cloning of a third mammalian Na+-Ca2+ exchanger, NCX3 J. Biol. Chem. 271 1996 24914 24921
21. D.A. Nicoll, M. Ottolia, L. Lu, Y. Lu, and K.D. Philipson A new topological model of the cardiac sarcolemmal Na+-Ca2+ exchanger J. Biol. Chem. 274 1999 910 917
22. D.A. Nicoll, M. Ottolia, and K.D. Philipson Toward a topological model of the NCX1 exchanger Ann. N.Y. Acad. Sci. 976 2002 11 18
23. M. Nister, C.H. Heldin, and B. Westermark Clonal variation in the production of a platelet-derived growth factor-like protein and expression of corresponding receptors in a human malignant glioma Cancer Res. 46 1986 332 340
24. T. Ota Complete sequencing and characterization of 21,243 full-length human cDNAs Nat. Genet. 36 2004 40 45
25. K.D. Philipson, and D.A. Nicoll Sodium-calcium exchange: a molecular perspective Annu. Rev. Physiol. 62 2000 111 133
26. K.D. Philipson, D.A. Nicoll, S. Matsuoka, L.V. Hryshko, D.O. Levitsky, and J.N. Weiss Molecular regulation of the Na(+)-Ca2+ exchanger Ann. N.Y. Acad. Sci. 779 1996 20 28
27. B.D. Quednau, D.A. Nicoll, and K.D. Philipson Tissue specificity and alternative splicing of the Na+/Ca2+ exchanger isoforms NCX1, NCX2, and NCX3 in rat Am. J. Physiol. 272 1997 C1250 C1261
28. B.D. Quednau, D.A. Nicoll, and K.D. Philipson The sodium/calcium exchanger family-SLC8 Pflugers Arch. 447 2004 543 548
29. R.F. Reilly, and D. Lattanzi Identification of a novel alternatively spliced isoform of the Na(+)-Ca2+ exchanger (NACA8) in heart Ann. N.Y. Acad. Sci. 779 1996 129 131
30. E.M. Schwarz, and S. Benzer Calx, a Na-Ca exchanger gene of Drosophila melanogaster Proc. Natl. Acad. Sci. U. S. A. 94 1997 10249 10254
31. T. Thurneysen, D.A. Nicoll, K.D. Philipson, and H. Porzig Sodium/calcium exchanger subtypes NCX1, NCX2 and NCX3 show cell-specific expression in rat hippocampus cultures Brain Res. Mol. Brain Res. 107 2002 145 156
32. F. Van Eylen, A. Kamagate, and A. Herchuelz A new Na/Ca exchanger splicing pattern identified in situ leads to a functionally active 70 kDa NH(2)-terminal protein Cell Calcium 30 2001 191 198