Variant of human enzyme sequesters reactive intermediate

Biochemistry

Volumn 44, Issue 11, 2005, Pages 4216-4221

  Ewalt, Karla L ^a   Yang, Xiang Lei ^a   Otero, Francella J ^a   Liu, Jianming ^a   Slike, Bonnie ^a   Schimmel, Paul ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; AMINO ACIDS; CATALYSIS; CELLS; HYDROLYSIS; PROTEINS; RNA; SYNTHESIS (CHEMICAL);

ENZYME-CATALYZED REACTIONS; HUMAN ENZYMES; TRNA;

ENZYMES;

ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; AMINO ACID; AMINO ACID TRANSFER RNA LIGASE; AMINOACYL TRANSFER RNA; INORGANIC PYROPHOSPHATASE; PHOSPHATE; PYROPHOSPHATE; TRANSFER RNA; TRYPTOPHAN TRANSFER RNA LIGASE; TYROSINE TRANSFER RNA LIGASE;

AMINOACYLATION; ARTICLE; CATALYSIS; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME STRUCTURE; HYDROLYSIS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; STRUCTURE ANALYSIS;

ADENOSINE MONOPHOSPHATE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CATALYSIS; DIPHOSPHATES; ENZYME ACTIVATION; HUMANS; KINETICS; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; POLYMORPHISM, GENETIC; TRYPTOPHAN; TRYPTOPHAN-TRNA LIGASE; VARIATION (GENETICS);

EID: 15544388342     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi048116l     Document Type: Article

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