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1
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0024946615
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High resolution proton magnetic resonance spectroscopy of biological fluids
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J.K. Nicholson, and I.D. Wilson High resolution proton magnetic resonance spectroscopy of biological fluids Prog. Nuclear Magn. Reson. Spectrosc. 21 1989 449 501
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Nicholson, J.K.1
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7344256122
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1H NMR spectroscopy of urine combined with pattern recognition
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1H NMR spectroscopy of urine combined with pattern recognition NMR Biomed. 11 1998 235 244
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NMR Biomed.
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Holmes, E.1
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Neidig, P.6
Connor, S.C.7
Connelly, J.8
Damment, S.J.P.9
Haselden, J.10
Nicholson, J.K.11
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3
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0023628652
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Solid-phase extraction chromatography and nuclear magnetic resonance spectrometry for the identification and isolation of drug metabolites in urine
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I.D. Wilson, and J.K. Nicholson Solid-phase extraction chromatography and nuclear magnetic resonance spectrometry for the identification and isolation of drug metabolites in urine Anal. Chem. 29 1987 2830 2832
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(1987)
Anal. Chem.
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Wilson, I.D.1
Nicholson, J.K.2
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4
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0030611827
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750 MHz spectroscopy characterization of the complex metabolic pattern of urine from patients with inborn errors of metabolism: 2-hydroxyglutaric aciduria and maple syrup urine disease
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E. Holmes, P.J.D. Foxall, M. Spraul, R.D. Farrant, and J.K. Nicholson 750 MHz spectroscopy characterization of the complex metabolic pattern of urine from patients with inborn errors of metabolism: 2-hydroxyglutaric aciduria and maple syrup urine disease J. Pharm. Biomed. Anal. 15 1997 1647 1659
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(1997)
J. Pharm. Biomed. Anal.
, vol.15
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Holmes, E.1
Foxall, P.J.D.2
Spraul, M.3
Farrant, R.D.4
Nicholson, J.K.5
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5
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0031051131
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Directly coupled 800 MHz HPLC-NMR spectroscopy of urine and its application to the identification of the major phase II metabolites of tolfenamic acid
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U.G. Sidelmann, U.B. Braumann, M. Hofmann, M. Spraul, J.C. Lindon, J.K. Nicholson, and S.H. Hansen Directly coupled 800 MHz HPLC-NMR spectroscopy of urine and its application to the identification of the major phase II metabolites of tolfenamic acid Anal. Chem. 69 1997 607 612
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(1997)
Anal. Chem.
, vol.69
, pp. 607-612
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Sidelmann, U.G.1
Braumann, U.B.2
Hofmann, M.3
Spraul, M.4
Lindon, J.C.5
Nicholson, J.K.6
Hansen, S.H.7
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6
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0024580448
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Investigation into the biochemical effects of region-specific nephrotoxins
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K.P.R. Gartland, F.W. Bonner, and J.K. Nicholson Investigation into the biochemical effects of region-specific nephrotoxins Mol. Pharmacol. 35 1989 242 250
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(1989)
Mol. Pharmacol.
, vol.35
, pp. 242-250
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Gartland, K.P.R.1
Bonner, F.W.2
Nicholson, J.K.3
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7
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0032694577
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Metabonomics: Understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
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J.K. Nicholson, J.C. Lindon, and E. Holmes Metabonomics: understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data Xenobiotica 29 1999 1181 1189
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(1999)
Xenobiotica
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Nicholson, J.K.1
Lindon, J.C.2
Holmes, E.3
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8
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0032517858
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The identification of novel biomarkers of renal toxicity using automatic data reduction techniques and PCA of proton NMR spectra of urine
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E. Holmes, S.C. Connor, A.W. Nicholls, S. Polley, J.K. Nicholson, J.C. Lindon, and J. Connelly The identification of novel biomarkers of renal toxicity using automatic data reduction techniques and PCA of proton NMR spectra of urine Chemom. Intell. Lab. Syst. 44 1998 251 261
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(1998)
Chemom. Intell. Lab. Syst.
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Holmes, E.1
Connor, S.C.2
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Polley, S.4
Nicholson, J.K.5
Lindon, J.C.6
Connelly, J.7
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9
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0035815463
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Non-destructive quantitation of spermine in human prostate tissue samples using HR H-1 NMR spectroscopy at 9.4 T
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L.L. Cheng, C.L. Wu, M.R. Smith, and R.G. Gonzalez Non-destructive quantitation of spermine in human prostate tissue samples using HR H-1 NMR spectroscopy at 9.4 T FEBS Lett. 494 2001 112 116
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FEBS Lett.
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Cheng, L.L.1
Wu, C.L.2
Smith, M.R.3
Gonzalez, R.G.4
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10
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0034672533
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The biochemical profile of rat testicular tissue as measured by magic angle spinning H-1 NMR spectroscopy
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J.L. Griffin, L.A. Walker, R.F. Shore, J.C. Lindon, and J.K. Nicholson The biochemical profile of rat testicular tissue as measured by magic angle spinning H-1 NMR spectroscopy FEBS Lett. 486 2000 224 229
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(2000)
FEBS Lett.
, vol.486
, pp. 224-229
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Griffin, J.L.1
Walker, L.A.2
Shore, R.F.3
Lindon, J.C.4
Nicholson, J.K.5
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12
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0025891393
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Application of pattern recognition methods to the analysis and classification of toxicological data derived from proton nuclear magnetic resonance spectroscopy of urine
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K.P.R. Gartland, C.R. Beddell, J.C. Lindon, and J.K. Nicholson Application of pattern recognition methods to the analysis and classification of toxicological data derived from proton nuclear magnetic resonance spectroscopy of urine Mol. Pharmacol. 39 1991 629 642
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(1991)
Mol. Pharmacol.
, vol.39
, pp. 629-642
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Gartland, K.P.R.1
Beddell, C.R.2
Lindon, J.C.3
Nicholson, J.K.4
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13
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0015079877
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α-Naphthylisothiocyanate (ANIT)-induced hepatotoxicity and disposition in various species
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F. Capizzo, and R.J. Roberts α-Naphthylisothiocyanate (ANIT)-induced hepatotoxicity and disposition in various species Toxicol. Appl. Pharmacol. 19 1971 176 187
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Toxicol. Appl. Pharmacol.
, vol.19
, pp. 176-187
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Capizzo, F.1
Roberts, R.J.2
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14
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84960960604
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Acute changes in liver after administration of thioacetamide
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D.N. Gupta Acute changes in liver after administration of thioacetamide J. Pathol. Bacteriol. 72 1956 183 192
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J. Pathol. Bacteriol.
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Gupta, D.N.1
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15
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Carbon tetrachloride hepatotoxicity
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R.O. Recknagel Carbon tetrachloride hepatotoxicity Pharmacol. Rev. 19 1967 145 208
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Pharmacol. Rev.
, vol.19
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Recknagel, R.O.1
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0034775361
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NMR and pattern recognition studies on the time-related metabolic effects of α-naphthylisothiocyanate on liver, urine and plasma in the rat: An integrative metabonomic approach
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N.J. Waters, E. Holmes, A. Willianms, C.J. Waterfield, R.D. Farrant, and J.K. Nicholson NMR and pattern recognition studies on the time-related metabolic effects of α-naphthylisothiocyanate on liver, urine and plasma in the rat: an integrative metabonomic approach Chem. Res. Toxicol. 14 2001 1401 1412
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(2001)
Chem. Res. Toxicol.
, vol.14
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Waters, N.J.1
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Farrant, R.D.5
Nicholson, J.K.6
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17
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0034861361
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Metabonomic investigations into hydrazine toxicity in the rat
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A.W. Nicholls, E. Holmes, J.C. lindon, J.P. Shockcor, R.D. Farrant, J.N. Haselden, S.J.P. Damment, C.J. Waterfield, and J.K. Nicholson Metabonomic investigations into hydrazine toxicity in the rat Chem. Res. Toxicol. 14 2001 975 987
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(2001)
Chem. Res. Toxicol.
, vol.14
, pp. 975-987
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Nicholls, A.W.1
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Lindon, J.C.3
Shockcor, J.P.4
Farrant, R.D.5
Haselden, J.N.6
Damment, S.J.P.7
Waterfield, C.J.8
Nicholson, J.K.9
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20
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0344493931
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1H nuclear magnetic resonance-based metabonomic techniques for the analysis of the biochemical effects of dietary isoflavones on human plasma profile
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1H nuclear magnetic resonance-based metabonomic techniques for the analysis of the biochemical effects of dietary isoflavones on human plasma profile Anal. Biochem. 323 2003 197 204
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Anal. Biochem.
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Solanky, K.S.1
Bailey, N.J.C.2
Beckwith-Hall, B.M.B.3
Davis, A.4
Bingham, S.5
Holmes, E.6
Nicholson, J.K.7
Cassidy, A.8
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21
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0028083271
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Pattern recognition classification of the site of nephrotoxicity based on metabolic data derived from proton nuclear magnetic resonance spectra of urine
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M.L. Anthony, B.C. Sweatman, C.R. Beddell, J.C. Lindon, and J.K. Nicholson Pattern recognition classification of the site of nephrotoxicity based on metabolic data derived from proton nuclear magnetic resonance spectra of urine Mol. Pharmacol. 46 1994 199 211
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Mol. Pharmacol.
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Anthony, M.L.1
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Beddell, C.R.3
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22
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0027052705
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Nuclear magnetic resonance spectroscopy and pattern recognition analysis of the biochemical process associated with the progression of and recovery from nephrotoxic lesions in the rat induced by mercury (II) chloride and 2-bromoethanamine
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E. Holmes, F.W. Bonner, B.C. Sweatman, J.C. Lindon, C.R. Beddell, E. Rahr, and J.K. Nicholson Nuclear magnetic resonance spectroscopy and pattern recognition analysis of the biochemical process associated with the progression of and recovery from nephrotoxic lesions in the rat induced by mercury (II) chloride and 2-bromoethanamine Mol. Pharmacol. 42 1992 922 930
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(1992)
Mol. Pharmacol.
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Holmes, E.1
Bonner, F.W.2
Sweatman, B.C.3
Lindon, J.C.4
Beddell, C.R.5
Rahr, E.6
Nicholson, J.K.7
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