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Volumn 8, Issue 1, 1996, Pages 91-99

Re-evaluation of the probabilities for productive rearrangements on the κ and λ loci

Author keywords

Allelic exclusion; B cell development; Ig gene rearrangement; Ig ; Isotypic exclusion; RS recombination; V J recombination

Indexed keywords

IMMUNOGLOBULIN KAPPA CHAIN; IMMUNOGLOBULIN LAMBDA CHAIN; IMMUNOGLOBULIN LIGHT CHAIN;

EID: 0030071522     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/8.1.91     Document Type: Article
Times cited : (52)

References (43)
  • 1
    • 0020534965 scopus 로고
    • Somatic generation of antibody diversity
    • Tonegawa, S. 1983. Somatic generation of antibody diversity Nature 302:575.
    • (1983) Nature , vol.302 , pp. 575
    • Tonegawa, S.1
  • 2
    • 0001499161 scopus 로고
    • Polypeptide chains of human gamma giobulin cellular localization by fluorescent antibody
    • Bernier, G. M. and Cebra, J. 1964. Polypeptide chains of human gamma giobulin cellular localization by fluorescent antibody. Science 144:1590.
    • (1964) Science , vol.144 , pp. 1590
    • Bernier, G.M.1    Cebra, J.2
  • 3
    • 0018929067 scopus 로고
    • Activity of multiple light chain genes in murine myeloma cells producing a single, functional light chain
    • Alt. F. W., Enea, V., Bothwell, A. L. M. and Baltimore, D 1980 Activity of multiple light chain genes in murine myeloma cells producing a single, functional light chain. Cell 21:1
    • (1980) Cell , vol.21 , pp. 1
    • Alt, F.W.1    Enea, V.2    Bothwell, A.L.M.3    Baltimore, D.4
  • 4
    • 0019455850 scopus 로고
    • Human immunoglobulin κ light-chain genes are deleted or rearranged in λ-producing B cells
    • Hieter, P. A, Korsmeyer, S J , Waldmann, T. A and Leder, P 1981. Human immunoglobulin κ light-chain genes are deleted or rearranged in λ-producing B cells Nature 290:368
    • (1981) Nature , vol.290 , pp. 368
    • Hieter, P.A.1    Korsmeyer, S.J.2    Waldmann, T.A.3    Leder, P.4
  • 5
    • 0019494043 scopus 로고
    • Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression
    • Coleclough, C , Perry, R. P., Karjalainen, K and Weigert, M. 1981. Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression Nature 290:372
    • (1981) Nature , vol.290 , pp. 372
    • Coleclough, C.1    Perry, R.P.2    Karjalainen, K.3    Weigert, M.4
  • 6
    • 0020464847 scopus 로고
    • Continuing κ-gene rearrangement in a cell line transformed by Abelson murine leukemia virus
    • Lewis, S , Rosenberg, N , Alt, F. and Baltimore, D 1982. Continuing κ-gene rearrangement in a cell line transformed by Abelson murine leukemia virus. Cell 30:807
    • (1982) Cell , vol.30 , pp. 807
    • Lewis, S.1    Rosenberg, N.2    Alt, F.3    Baltimore, D.4
  • 8
    • 0021095405 scopus 로고
    • Chance, necessity and antibody gene dynamics
    • Coleciough, C. 1983 Chance, necessity and antibody gene dynamics Nature 303:23.
    • (1983) Nature , vol.303 , pp. 23
    • Coleciough, C.1
  • 9
    • 0025093522 scopus 로고
    • Murine lambda gene rearrangements, the stochastic model prevails over the ordered model
    • Nadel, B., Cazenave, P-A. and Sanchez, P. 1990. Murine lambda gene rearrangements, the stochastic model prevails over the ordered model EMBO J. 9:435.
    • (1990) EMBO J. , vol.9 , pp. 435
    • Nadel, B.1    Cazenave, P.-A.2    Sanchez, P.3
  • 10
    • 0025523372 scopus 로고
    • Immunoglobulin λ gene rearrangement can precede κ gene rearrangement
    • Berg, J, McDowell, M, Jäck, H -M and Wabl, M. 1990, Immunoglobulin λ gene rearrangement can precede κ gene rearrangement. Dev Immunol, 1:53.
    • (1990) Dev Immunol , vol.1 , pp. 53
    • Berg, J.1    McDowell, M.2    Jäck, H.-M.3    Wabl, M.4
  • 11
    • 0025439518 scopus 로고
    • The protection: The unit of humoral immunity selected by evolution
    • Cohn, M. and Langman, R. E. 1990. The protection: the unit of humoral immunity selected by evolution, Immunol. Rev. 115 11
    • (1990) Immunol. Rev. , vol.115 , pp. 11
    • Cohn, M.1    Langman, R.E.2
  • 12
    • 0025772885 scopus 로고
    • Independent rearrangement of lgλ genes in tissue culture-derived murine B cell lines
    • Felsher, D. W, Ando, D T and Braun, J. 1991. Independent rearrangement of lgλ genes in tissue culture-derived murine B cell lines Int Immunol. 3:711.
    • (1991) Int Immunol. , vol.3 , pp. 711
    • Felsher, D.W.1    Ando, D.T.2    Braun, J.3
  • 13
    • 0025788230 scopus 로고
    • Mouse κ light-chain recombination signal sequences mediate recombination more frequently than do those of λ light chain
    • Ramsden, D. A. and Wu, G. E 1991. Mouse κ light-chain recombination signal sequences mediate recombination more frequently than do those of λ light chain Proc. Natl Acad. Sci. USA 88:10721.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 10721
    • Ramsden, D.A.1    Wu, G.E.2
  • 14
    • 0028966195 scopus 로고
    • The proportion of B-cell subsets expressing κ and λ light chains changes following antigenic selection
    • Langman, R E and Cohn, M. 1995 The proportion of B-cell subsets expressing κ and λ light chains changes following antigenic selection, Immunol Today 16:141.
    • (1995) Immunol Today , vol.16 , pp. 141
    • Langman, R.E.1    Cohn, M.2
  • 15
    • 0027189754 scopus 로고
    • Deletion of the immunoglobulin κ chain intron enhancer abolishes κ chain gene rearrangement in c/s but not λ chain gene rearrangement in frans
    • Takeda, S., Zou, Y.-R., Bluethmann, H., Kitamura, D , Muller, U and Rajewsky, K. 1993 Deletion of the immunoglobulin κ chain intron enhancer abolishes κ chain gene rearrangement in c/s but not λ chain gene rearrangement in frans EMBO J. 12:2329
    • (1993) EMBO J. , vol.12 , pp. 2329
    • Takeda, S.1    Zou, Y.-R.2    Bluethmann, H.3    Kitamura, D.4    Muller, U.5    Rajewsky, K.6
  • 16
    • 0027447365 scopus 로고
    • Gene targeting in the IgK locus: Efficient generation of λ chain-expressing B cells, independent of gene rearrangement in lgK
    • Zou, Y-R , Takeda, S and Rajewsky, K 1993. Gene targeting in the IgK locus: efficient generation of λ chain-expressing B cells, independent of gene rearrangement in lgK. EMBO J. 12:811
    • (1993) EMBO J. , vol.12 , pp. 811
    • Zou, Y.-R.1    Takeda, S.2    Rajewsky, K.3
  • 18
    • 0028198054 scopus 로고
    • Probing immune functions in RAG-deficient mice Curr
    • Chen, J., Shinkai, Y. Young, F and Alt, F. W. 1994 Probing immune functions in RAG-deficient mice Curr. Opin. Immunol 6:313
    • (1994) Opin. Immunol , vol.6 , pp. 313
    • Chen, J.1    Shinkai, Y.2    Young, F.3    Alt, F.W.4
  • 19
    • 0019428880 scopus 로고
    • B220: A B cell-specific member of the T200 glycoprotem family
    • Coffman. R. L. and Weissman, I. L 1981. B220: a B cell-specific member of the T200 glycoprotem family Nature 289:681.
    • (1981) Nature , vol.289 , pp. 681
    • Coffman, R.L.1    Weissman, I.L.2
  • 20
    • 0021346615 scopus 로고
    • Allotypic specificities of murine lgD and lgM recognized by monoclonal antibodies
    • Stall, A. and Loken, M. 1984. Allotypic specificities of murine lgD and lgM recognized by monoclonal antibodies. J. Immunol. 132:787.
    • (1984) J. Immunol. , vol.132 , pp. 787
    • Stall, A.1    Loken, M.2
  • 21
    • 0018307692 scopus 로고
    • The use of avidin-biotin interaction in immunoenzymatic techniques
    • Guesdon, J.-L , Ternynck, T and Avrameas, S. 1979 The use of avidin-biotin interaction in immunoenzymatic techniques. J. Histochem. Cytochem. 27:1131.
    • (1979) J. Histochem. Cytochem. , vol.27 , pp. 1131
    • Guesdon, J.-L.1    Ternynck, T.2    Avrameas, S.3
  • 22
    • 0024444922 scopus 로고
    • Flowcytometric analysis of cell proliferation dynamics in the B cell compartment of the mouse
    • Förster, I, Vieira, P. and Rajewsky, K. 1989. Flowcytometric analysis of cell proliferation dynamics in the B cell compartment of the mouse. Int. Immunol. 1:321
    • (1989) Int. Immunol. , vol.1 , pp. 321
    • Förster, I.1    Vieira, P.2    Rajewsky, K.3
  • 23
    • 0025801026 scopus 로고
    • Proliferation kinetics and the iifespan of B cells in central and peripheral lymphoid organs
    • Osmond, D. D 1991, Proliferation kinetics and the iifespan of B cells in central and peripheral lymphoid organs Curr Opin. Immunol. 3:179
    • (1991) Curr Opin. Immunol. , vol.3 , pp. 179
    • Osmond, D.D.1
  • 24
    • 0025766890 scopus 로고
    • Molecular and cellular origins of B lymphocyte diversity
    • Rolink, A. and Melchers, F. 1991 Molecular and cellular origins of B lymphocyte diversity. Cell 66:1081
    • (1991) Cell , vol.66 , pp. 1081
    • Rolink, A.1    Melchers, F.2
  • 25
    • 0028179068 scopus 로고
    • The expression of Vpre-B/λ5 surrogate light chain in early bone marrow precursor B cells of normal and B cell-deficient mutant mice
    • Karasuyama, H., Rolink, A., Shinkai, Y, Young, F, Alt, F. W. and Melchers, F 1994 The expression of Vpre-B/λ5 surrogate light chain in early bone marrow precursor B cells of normal and B cell-deficient mutant mice. Cell 77:33
    • (1994) Cell , vol.77 , pp. 33
    • Karasuyama, H.1    Rolink, A.2    Shinkai, Y.3    Young, F.4    Alt, F.W.5    Melchers, F.6
  • 26
    • 0020593691 scopus 로고
    • Surface antigen expression and immunoglobulin gene rearrangement during mouse pre-B cell development
    • Coffman, R. L. 1982. Surface antigen expression and immunoglobulin gene rearrangement during mouse pre-B cell development, Immunol. Rev. 69:5.
    • (1982) Immunol. Rev. , vol.69 , pp. 5
    • Coffman, R.L.1
  • 27
    • 0029063042 scopus 로고
    • The status of lg loci rearrangements in single cells from different stages of B cell development
    • ten Boekel, E., Melchers, F. and Rolink, A. 1995 The status of lg loci rearrangements in single cells from different stages of B cell development, Int Immunol.
    • (1995) Int Immunol.
    • Ten Boekel, E.1    Melchers, F.2    Rolink, A.3
  • 28
    • 0001411939 scopus 로고
    • On the structure of normal light chains from mammals and birds, evolutionary and genetic implications
    • Sterzl. J and Hiha, I., eds, Academic Press, New York
    • Hood, L , Grant, J A and Sox, H. C , Jr 1969 On the structure of normal light chains from mammals and birds, evolutionary and genetic implications. In Sterzl. J and Hiha, I., eds, Developmental Aspects of Antibody Formation and Structure, vol. 1, p 283. Academic Press, New York.
    • (1969) Developmental Aspects of Antibody Formation and Structure , vol.1 , pp. 283
    • Hood, L.1    Grant, J.A.2    Sox Jr., H.C.3
  • 29
    • 0019466717 scopus 로고
    • κ/λ shifts do not occur during maturation of murine B cells
    • McGuire, K L. and Vitetta, E S. 1981. κ/λ shifts do not occur during maturation of murine B cells. J. Immunol. 127:1670.
    • (1981) J. Immunol. , vol.127 , pp. 1670
    • McGuire, K.L.1    Vitetta, E.S.2
  • 30
    • 0027943184 scopus 로고
    • Light chain editing in κ-deficient animals: A potential mechanism of B cell tolerance
    • Prak, E -L., Trounstine, M., Huszar, D. and Weigert, M. 1994. Light chain editing in κ-deficient animals: a potential mechanism of B cell tolerance. J. Exp Med. 180:1805.
    • (1994) J. Exp Med. , vol.180 , pp. 1805
    • Prak, E.L.1    Trounstine, M.2    Huszar, D.3    Weigert, M.4
  • 32
    • 0028245640 scopus 로고
    • κ light chain rearrangement in mouse fetal liver
    • Ramsen, D A., Paige, C J and Wu, G. E. 1994. κ light chain rearrangement in mouse fetal liver. J Immunol. 153:1150.
    • (1994) J Immunol. , vol.153 , pp. 1150
    • Ramsen, D.A.1    Paige, C.J.2    Wu, G.E.3
  • 33
    • 84967860680 scopus 로고
    • Double recombination of a single immunoglobulin κ-chain allele: Implications for the mechanism of rearrangement
    • Feddersen, R. M and Van Ness, B. G 1985 Double recombination of a single immunoglobulin κ-chain allele: implications for the mechanism of rearrangement. Proc. Natl Acad. Sci. USA 32:4792.
    • (1985) Proc. Natl Acad. Sci. USA , vol.32 , pp. 4792
    • Feddersen, R.M.1    Van Ness, B.G.2
  • 34
    • 0023578923 scopus 로고
    • How immunoglobulin Vκ genes rearrange
    • Shapiro, M. A and Weigert, M. 1987 How immunoglobulin Vκ genes rearrange. J Immunol. 139:3834.
    • (1987) J Immunol. , vol.139 , pp. 3834
    • Shapiro, M.A.1    Weigert, M.2
  • 35
    • 0027192988 scopus 로고
    • V(D)J recombination in B cells is impaired but not blocked by targeted deletion of the immunoglobulin heavy chain intron enhancer
    • Serwe, M and Sablitzky, F. 1993. V(D)J recombination in B cells is impaired but not blocked by targeted deletion of the immunoglobulin heavy chain intron enhancer EMBO J. 12:2321.
    • (1993) EMBO J. , vol.12 , pp. 2321
    • Serwe, M.1    Sablitzky, F.2
  • 37
    • 0025729069 scopus 로고
    • Deletion of ixmmunoglobulin C region characterized by the circular excision products in mouse splenocyte
    • Shimizu, T., Iwasato, T and Yamagishi. H. 1991. Deletion of ixmmunoglobulin C region characterized by the circular excision products in mouse splenocyte J Exp. Med. 173:1065.
    • (1991) J Exp. Med. , vol.173 , pp. 1065
    • Shimizu, T.1    Iwasato, T.2    Yamagishi, H.3
  • 38
    • 0021274530 scopus 로고
    • Novel κ light-chain gene rearrangements in mouse λ light chain-producing B lymphocytes
    • Durdik, J., Moore, M W. and Selsing, E. 1984. Novel κ light-chain gene rearrangements in mouse λ light chain-producing B lymphocytes Nature 307:749
    • (1984) Nature , vol.307 , pp. 749
    • Durdik, J.1    Moore, M.W.2    Selsing, E.3
  • 39
    • 0021870867 scopus 로고
    • A uniform deleting element mediates the loss of κ genes in human B cells
    • Siminovitch, K. A., Bakhshi, A, Goldmand, P. and Korsmeyer, S. J 1985. A uniform deleting element mediates the loss of κ genes in human B cells Nature 316 260
    • (1985) Nature , vol.316 , pp. 260
    • Siminovitch, K.A.1    Bakhshi, A.2    Goldmand, P.3    Korsmeyer, S.J.4
  • 40
    • 0011955092 scopus 로고
    • Deletions of κ chain constant region genes in mouse λ chain-producing B cells involve intrachromosomal DNA recombinations similar to V-J joining
    • Moore, M W, Durdik, J . Persiani, D M and Selsing, E. 1985. Deletions of κ chain constant region genes in mouse λ chain-producing B cells involve intrachromosomal DNA recombinations similar to V-J joining. Proc. Natl Acad. Sci. USA 82:6211.
    • (1985) Proc. Natl Acad. Sci. USA , vol.82 , pp. 6211
    • Moore, M.W.1    Durdik, J.2    Persiani, D.M.3    Selsing, E.4
  • 41
    • 0022559806 scopus 로고
    • κ gene segment and the kappa deleting element are closely linked
    • κ gene segment and the kappa deleting element are closely linked. Nucleic Acids Res 14:4591
    • (1986) Nucleic Acids Res , vol.14 , pp. 4591
    • Klobeck, H.G.1    Zachau, H.G.2
  • 42
    • 0025345213 scopus 로고
    • A physical map and analysis of the murine Cc-RS region show the presence of a conserved element
    • Müller, B., Stappert, H and Reth, M. 1990. A physical map and analysis of the murine Cc-RS region show the presence of a conserved element. Eur J. Immunol 20 409
    • (1990) Eur J. Immunol , vol.20 , pp. 409
    • Müller, B.1    Stappert, H.2    Reth, M.3
  • 43
    • 0025730210 scopus 로고
    • Vλ-Jλ rearrangements are restricted within a V-J-C recombination unit in the mouse
    • Sanchez, P., Nadel, B. and Cazenave, P.-A. 1991 Vλ-Jλ rearrangements are restricted within a V-J-C recombination unit in the mouse. Eur J. Immunol 21 907
    • (1991) Eur J. Immunol , vol.21 , pp. 907
    • Sanchez, P.1    Nadel, B.2    Cazenave, P.-A.3


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