메뉴 건너뛰기




Volumn 48, Issue 2-3, 2001, Pages 265-300

Noncompartmentally-based pharmacokinetic modeling

Author keywords

Convolution; Deconvolution; Disposition decomposition; Linear operators; Linear systems analysis; Mean residence times; Mean transit times; Nonparametric pharmacokinetics; Pharmacokinetic modeling; Pharmacokinetic response mapping

Indexed keywords

CONVOLUTION; DECOMPOSITION; DRUG DOSAGE; SYSTEMS ANALYSIS;

EID: 0035844740     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(01)00119-3     Document Type: Review
Times cited : (62)

References (53)
  • 1
    • 0021488451 scopus 로고
    • Compartmental vs. noncompartmental modeling for two accessible pools
    • Cobelli C., Toffolo G. Compartmental vs. noncompartmental modeling for two accessible pools. Am. J. Physiol. 247:1984;R488-496.
    • (1984) Am. J. Physiol. , vol.247
    • Cobelli, C.1    Toffolo, G.2
  • 2
    • 0018099994 scopus 로고
    • Linear systems analysis in pharmacokinetics
    • Cutler D.J. Linear systems analysis in pharmacokinetics. J. Pharmacokinet. Biopharm. 6:1978;265-282.
    • (1978) J. Pharmacokinet. Biopharm. , vol.6 , pp. 265-282
    • Cutler, D.J.1
  • 3
    • 0025810563 scopus 로고
    • Noncompartmental versus compartmental modelling in clinical pharmacokinetics
    • Gillespie W.R. Noncompartmental versus compartmental modelling in clinical pharmacokinetics. Clin. Pharmacokinet. 20:1991;253-262.
    • (1991) Clin. Pharmacokinet. , vol.20 , pp. 253-262
    • Gillespie, W.R.1
  • 4
    • 0021431509 scopus 로고
    • Multiexponential, multicompartmental, and noncompartmental modeling. II. Data analysis and statistical considerations
    • Landaw E.M., DiStefano J.J.d. Multiexponential, multicompartmental, and noncompartmental modeling. II. Data analysis and statistical considerations. Am. J. Physiol. 246:1984;R665-677.
    • (1984) Am. J. Physiol. , vol.246
    • Landaw, E.M.1    DiStefano, J.J.d.2
  • 5
    • 0023375720 scopus 로고
    • Model and model-independent methods of describing pharmacokinetics: The advantages, drawbacks and [interrelationship]
    • Piotrovskii V.K. Model and model-independent methods of describing pharmacokinetics: the advantages, drawbacks and interrelationship]. Antibiot. Med. Biotekhnol. 32:1987;492-497.
    • (1987) Antibiot. Med. Biotekhnol. , vol.32 , pp. 492-497
    • Piotrovskii, V.K.1
  • 7
    • 0023673255 scopus 로고
    • System approaches in pharmacokinetics: I. Basic concepts
    • Veng-Pedersen P. System approaches in pharmacokinetics: I. Basic concepts. J. Clin. Pharmacol. 28:1988;1-5.
    • (1988) J. Clin. Pharmacol. , vol.28 , pp. 1-5
    • Veng-Pedersen, P.1
  • 8
    • 0023958994 scopus 로고
    • System approaches in pharmacokinetics. II. Applications
    • Veng-Pedersen P. System approaches in pharmacokinetics. II. Applications. J. Clin. Pharmacol. 28:1988;97-104.
    • (1988) J. Clin. Pharmacol. , vol.28 , pp. 97-104
    • Veng-Pedersen, P.1
  • 9
    • 0023693083 scopus 로고
    • Linear and nonlinear system approaches in pharmacokinetics. How much do they have to offer? I. General considerations
    • Veng-Pedersen P. Linear and nonlinear system approaches in pharmacokinetics. How much do they have to offer? I. General considerations. J. Pharmacokin. Biopharm. 16:1988;413-472.
    • (1988) J. Pharmacokin. Biopharm. , vol.16 , pp. 413-472
    • Veng-Pedersen, P.1
  • 10
    • 0024206966 scopus 로고
    • Linear and nonlinear system approaches in pharmacokinetics. How much do they have to offer? II. The response mapping operator (RMO) approach
    • Veng-Pedersen P. Linear and nonlinear system approaches in pharmacokinetics. How much do they have to offer? II. The response mapping operator (RMO) approach. J. Pharmacokin. Biopharm. 16:1988;543-571.
    • (1988) J. Pharmacokin. Biopharm. , vol.16 , pp. 543-571
    • Veng-Pedersen, P.1
  • 11
    • 0027718065 scopus 로고
    • Two constrained deconvolution methods using spline functions
    • Verotta D. Two constrained deconvolution methods using spline functions. J. Pharmacokinet. Biopharm. 21:1993;609-636.
    • (1993) J. Pharmacokinet. Biopharm. , vol.21 , pp. 609-636
    • Verotta, D.1
  • 12
    • 0027691238 scopus 로고
    • Estimation and model selection in constrained deconvolution
    • Verotta D. Estimation and model selection in constrained deconvolution. Ann. Biomed. Eng. 21:1993;605-620.
    • (1993) Ann. Biomed. Eng. , vol.21 , pp. 605-620
    • Verotta, D.1
  • 13
    • 0029556136 scopus 로고
    • A nonparametric subject-specific population method for deconvolution. II. External validation
    • Fattinger K.E., Verotta D. A nonparametric subject-specific population method for deconvolution. II. External validation. J. Pharmacokinet. Biopharm. 23:1995;611-634.
    • (1995) J. Pharmacokinet. Biopharm. , vol.23 , pp. 611-634
    • Fattinger, K.E.1    Verotta, D.2
  • 14
    • 0029554724 scopus 로고
    • A nonparametric subject-specific population method for deconvolution. I. Description, internal validation, and real data examples
    • Fattinger K.E., Verotta D. A nonparametric subject-specific population method for deconvolution. I. Description, internal validation, and real data examples. J. Pharmacokinet. Biopharm. 23:1995;581-610.
    • (1995) J. Pharmacokinet. Biopharm. , vol.23 , pp. 581-610
    • Fattinger, K.E.1    Verotta, D.2
  • 15
    • 0019277294 scopus 로고
    • An algorithm and computer program for deconvolution in linear pharmacokinetics [see comments]
    • Veng-Pedersen P. An algorithm and computer program for deconvolution in linear pharmacokinetics [see comments]. J. Pharmacokinet. Biopharm. 8:1980;463-481.
    • (1980) J. Pharmacokinet. Biopharm. , vol.8 , pp. 463-481
    • Veng-Pedersen, P.1
  • 16
    • 0022408834 scopus 로고
    • Deconvolution applied to the kinetics of extracorporal drug removal. Haemodialysis of cefsulodin
    • Gillespie W.R., Veng-Pedersen P., Gibson T.P. Deconvolution applied to the kinetics of extracorporal drug removal. Haemodialysis of cefsulodin. Eur. J. Clin. Pharmacol. 29:1985;503-509.
    • (1985) Eur. J. Clin. Pharmacol. , vol.29 , pp. 503-509
    • Gillespie, W.R.1    Veng-Pedersen, P.2    Gibson, T.P.3
  • 17
    • 0021842586 scopus 로고
    • Gastrointestinal bioavailability: Determination of in vivo release profiles of solid oral dosage forms by deconvolution
    • Gillespie W.R., Veng-Pedersen P. Gastrointestinal bioavailability: determination of in vivo release profiles of solid oral dosage forms by deconvolution. Biopharm. Drug Dispos. 6:1985;351-355.
    • (1985) Biopharm. Drug Dispos. , vol.6 , pp. 351-355
    • Gillespie, W.R.1    Veng-Pedersen, P.2
  • 18
    • 0022344635 scopus 로고
    • A polyexponential deconvolution method. Evaluation of the 'gastrointestinal bioavailability' and mean in vivo dissolution time of some ibuprofen dosage forms
    • Gillespie W.R., Veng-Pedersen P. A polyexponential deconvolution method. Evaluation of the 'gastrointestinal bioavailability' and mean in vivo dissolution time of some ibuprofen dosage forms. J. Pharmacokin. Biopharm. 13:1985;289-307.
    • (1985) J. Pharmacokin. Biopharm. , vol.13 , pp. 289-307
    • Gillespie, W.R.1    Veng-Pedersen, P.2
  • 19
    • 0019351711 scopus 로고
    • Pharmacokinetic analysis by linear system approach I: Cimetidine bioavailability and second peak phenomenon
    • Veng Pedersen P. Pharmacokinetic analysis by linear system approach I: cimetidine bioavailability and second peak phenomenon. J. Pharm. Sci. 70:1981;32-38.
    • (1981) J. Pharm. Sci. , vol.70 , pp. 32-38
    • Veng Pedersen, P.1
  • 20
    • 0018190102 scopus 로고
    • Numerical deconvolution by least squares: Use of prescribed input functions
    • Cutler D.J. Numerical deconvolution by least squares: use of prescribed input functions. J. Pharmacokinet. Biopharm. 6:1978;227-241.
    • (1978) J. Pharmacokinet. Biopharm. , vol.6 , pp. 227-241
    • Cutler, D.J.1
  • 21
    • 0029837394 scopus 로고    scopus 로고
    • Five modified numerical deconvolution methods for biopharmaceutics and pharmacokinetics studies
    • Yu Z., Schwartz J.B., Sugita E.T., Foehl H.C. Five modified numerical deconvolution methods for biopharmaceutics and pharmacokinetics studies. Biopharm. Drug Dispos. 17:1996;521-540.
    • (1996) Biopharm. Drug Dispos. , vol.17 , pp. 521-540
    • Yu, Z.1    Schwartz, J.B.2    Sugita, E.T.3    Foehl, H.C.4
  • 23
    • 0025194535 scopus 로고
    • Bioavailability estimation by semisimultaneous drug administration: A Monte Carlo simulation study
    • Karlsson M.O., Bredberg U. Bioavailability estimation by semisimultaneous drug administration: a Monte Carlo simulation study. J. Pharmacokinet. Biopharm. 18:1990;103-120.
    • (1990) J. Pharmacokinet. Biopharm. , vol.18 , pp. 103-120
    • Karlsson, M.O.1    Bredberg, U.2
  • 24
    • 0023183157 scopus 로고
    • Drug absorption evaluation in the presence of changes in clearance: An algorithm and computer program for deconvolution with exact clearance correction
    • Veng-Pedersen P. Drug absorption evaluation in the presence of changes in clearance: an algorithm and computer program for deconvolution with exact clearance correction. J. Pharmacokin. Biopharm. 8:1987;185-203.
    • (1987) J. Pharmacokin. Biopharm. , vol.8 , pp. 185-203
    • Veng-Pedersen, P.1
  • 27
    • 34250263445 scopus 로고
    • Smoothing noise data with spline functions
    • Craven P., Wahba G. Smoothing noise data with spline functions. Numer. Math. 31:1979;377-403.
    • (1979) Numer. Math. , vol.31 , pp. 377-403
    • Craven, P.1    Wahba, G.2
  • 29
    • 0029347526 scopus 로고
    • WENDEC: A deconvolution program for processing hormone time-series
    • De Nicolao G., De Nicolao A. WENDEC: a deconvolution program for processing hormone time-series. Comput. Methods Programs Biomed. 47:1995;237-252.
    • (1995) Comput. Methods Programs Biomed. , vol.47 , pp. 237-252
    • De Nicolao, G.1    De Nicolao, A.2
  • 30
    • 0002970891 scopus 로고
    • Smoothing noise data with spline functions
    • Hutchinson M.F., deHoog F.R. Smoothing noise data with spline functions. Numer. Math. 47:1985;99-106.
    • (1985) Numer. Math. , vol.47 , pp. 99-106
    • Hutchinson, M.F.1    DeHoog, F.R.2
  • 31
    • 0028146842 scopus 로고
    • Relative bioavailability of RRR- and all-rac-alpha-tocopheryl acetate in humans: Studies using deuterated compounds
    • Acuff R.V., Thedford S.S., Hidiroglou N.N., Papas A.M., Odom T.A. Jr. Relative bioavailability of RRR- and all-rac-alpha-tocopheryl acetate in humans: studies using deuterated compounds. Am. J. Clin. Nutr. 60:1994;397-402.
    • (1994) Am. J. Clin. Nutr. , vol.60 , pp. 397-402
    • Acuff, R.V.1    Thedford, S.S.2    Hidiroglou, N.N.3    Papas, A.M.4    Odom, T.A.Jr.5
  • 32
    • 0029760078 scopus 로고    scopus 로고
    • The use of stable isotope labeling and liquid chromatography/tandem mass spectrometry techniques to study the pharmacokinetics and bioavailability of the antimigraine drug, MK-0462 (rizatriptan) in dogs
    • Barrish A., Olah T.V., Gatto G.J., Michel K.B., Dobrinska M.R., Gilbert J.D. The use of stable isotope labeling and liquid chromatography/tandem mass spectrometry techniques to study the pharmacokinetics and bioavailability of the antimigraine drug, MK-0462 (rizatriptan) in dogs. Rapid Commun. Mass Spectrom. 10:1996;1033-1037.
    • (1996) Rapid Commun. Mass Spectrom. , vol.10 , pp. 1033-1037
    • Barrish, A.1    Olah, T.V.2    Gatto, G.J.3    Michel, K.B.4    Dobrinska, M.R.5    Gilbert, J.D.6
  • 33
    • 0029897299 scopus 로고    scopus 로고
    • Investigation of nifedipine absorption in different regions of the human gastrointestinal (GI) tract after simultaneous administration of 13C- and 12C-nifedipine
    • Bode H., Brendel E., Ahr G., Fuhr U., Harder S., Staib A.H. Investigation of nifedipine absorption in different regions of the human gastrointestinal (GI) tract after simultaneous administration of 13C- and 12C-nifedipine. Eur. J. Clin. Pharmacol. 50:1996;195-201.
    • (1996) Eur. J. Clin. Pharmacol. , vol.50 , pp. 195-201
    • Bode, H.1    Brendel, E.2    Ahr, G.3    Fuhr, U.4    Harder, S.5    Staib, A.H.6
  • 34
    • 0028941615 scopus 로고
    • Estimation of the absolute bioavailability of flecainide using stable isotope technique
    • Hage K., Buhl K., Fischer C., Knebel N.G. Estimation of the absolute bioavailability of flecainide using stable isotope technique. Eur. J. Clin. Pharmacol. 48:1995;51-55.
    • (1995) Eur. J. Clin. Pharmacol. , vol.48 , pp. 51-55
    • Hage, K.1    Buhl, K.2    Fischer, C.3    Knebel, N.G.4
  • 35
    • 0028595948 scopus 로고
    • Stable isotope methodology for studying the performance of metoprolol Oros tablets in comparison to conventional and slow release formulations
    • Richard J., Cardot J.M., Godbillon J. Stable isotope methodology for studying the performance of metoprolol Oros tablets in comparison to conventional and slow release formulations. Eur. J. Drug Metab. Pharmacokinet. 19:1994;375-380.
    • (1994) Eur. J. Drug Metab. Pharmacokinet. , vol.19 , pp. 375-380
    • Richard, J.1    Cardot, J.M.2    Godbillon, J.3
  • 36
    • 0021745125 scopus 로고
    • Theorems and implications of a model independent elimination/distribution function decomposition of linear and some nonlinear drug dispositions. I. Derivations and theoretical analysis
    • Veng-Pedersen P. Theorems and implications of a model independent elimination/distribution function decomposition of linear and some nonlinear drug dispositions. I. Derivations and theoretical analysis. J. Pharmacokinet. Biopharm. 12:1984;627-648.
    • (1984) J. Pharmacokinet. Biopharm. , vol.12 , pp. 627-648
    • Veng-Pedersen, P.1
  • 37
    • 0024841883 scopus 로고
    • Mean time parameters in pharmacokinetics. Definition computation and clinical implications (Part II)
    • Veng-Pedersen P. Mean time parameters in pharmacokinetics. Definition computation and clinical implications (Part II). Clin. Pharmacokinet. 17:1989;424-440.
    • (1989) Clin. Pharmacokinet. , vol.17 , pp. 424-440
    • Veng-Pedersen, P.1
  • 38
    • 0024461865 scopus 로고
    • Mean time parameters in pharmacokinetics. Definition, computation and clinical implications (Part I)
    • Veng-Pedersen P. Mean time parameters in pharmacokinetics. Definition, computation and clinical implications (Part I). Clin. Pharmacokinet. 17:1989;345-366.
    • (1989) Clin. Pharmacokinet. , vol.17 , pp. 345-366
    • Veng-Pedersen, P.1
  • 39
    • 0023237408 scopus 로고
    • Mean residence time for drugs subject to reversible metabolism
    • Aarons L. Mean residence time for drugs subject to reversible metabolism. J. Pharm. Pharmacol. 39:1987;565-567.
    • (1987) J. Pharm. Pharmacol. , vol.39 , pp. 565-567
    • Aarons, L.1
  • 40
    • 0029926360 scopus 로고    scopus 로고
    • Mean input times of three oral chlorprothixene formulations assessed by an enhanced least-squares deconvolution method
    • Bagli M., Suverkrup R., Rao M.L., Bode H. Mean input times of three oral chlorprothixene formulations assessed by an enhanced least-squares deconvolution method. J. Pharm. Sci. 85:1996;434-439.
    • (1996) J. Pharm. Sci. , vol.85 , pp. 434-439
    • Bagli, M.1    Suverkrup, R.2    Rao, M.L.3    Bode, H.4
  • 42
    • 0027518379 scopus 로고
    • Mean residence time of oral drugs undergoing first-pass and linear reversible metabolism
    • Cheng H., Jusko W.J. Mean residence time of oral drugs undergoing first-pass and linear reversible metabolism. Pharm. Res. 10:1993;8-13.
    • (1993) Pharm. Res. , vol.10 , pp. 8-13
    • Cheng, H.1    Jusko, W.J.2
  • 43
    • 0022471096 scopus 로고
    • A simple method for obtaining the mean residence time of metabolites in the body
    • Veng-Pedersen P. A simple method for obtaining the mean residence time of metabolites in the body. J. Pharm. Sci. 75:1986;818-819.
    • (1986) J. Pharm. Sci. , vol.75 , pp. 818-819
    • Veng-Pedersen, P.1
  • 44
    • 0025773614 scopus 로고
    • Stochastic interpretation of linear pharmacokinetics: A linear system analysis approach
    • Veng-Pedersen P. Stochastic interpretation of linear pharmacokinetics: a linear system analysis approach. J. Pharm. Sci. 80:1991;621-631.
    • (1991) J. Pharm. Sci. , vol.80 , pp. 621-631
    • Veng-Pedersen, P.1
  • 45
    • 0021745698 scopus 로고
    • Mean residence time in peripheral tissue: A linear disposition parameter useful for evaluating a drug's tissue distribution
    • Veng-Pedersen P., Gillespie W. Mean residence time in peripheral tissue: a linear disposition parameter useful for evaluating a drug's tissue distribution. J. Pharmacokinet. Biopharm. 12:1984;535-543.
    • (1984) J. Pharmacokinet. Biopharm. , vol.12 , pp. 535-543
    • Veng-Pedersen, P.1    Gillespie, W.2
  • 46
    • 0022092170 scopus 로고
    • The mean residence time of drugs in the systemic circulation
    • Veng-Pedersen P., Gillespie W. The mean residence time of drugs in the systemic circulation. J. Pharm. Sci. 74:1985;791-792.
    • (1985) J. Pharm. Sci. , vol.74 , pp. 791-792
    • Veng-Pedersen, P.1    Gillespie, W.2
  • 47
    • 0022889587 scopus 로고
    • Single pass mean residence time in peripheral tissues: A distribution parameter intrinsic to the tissue affinity of a drug
    • Veng-Pedersen P., Gillespie W.R. Single pass mean residence time in peripheral tissues: a distribution parameter intrinsic to the tissue affinity of a drug. J. Pharm. Sci. 75:1986;1119-1126.
    • (1986) J. Pharm. Sci. , vol.75 , pp. 1119-1126
    • Veng-Pedersen, P.1    Gillespie, W.R.2
  • 48
    • 0026095848 scopus 로고
    • Mean time parameters for generalized physiological flow models (semihomogeneous linear systems)
    • Verotta D., Sheiner L.B., Beal S.L. Mean time parameters for generalized physiological flow models (semihomogeneous linear systems). J. Pharmacokinet. Biopharm. 19:1991;319-331.
    • (1991) J. Pharmacokinet. Biopharm. , vol.19 , pp. 319-331
    • Verotta, D.1    Sheiner, L.B.2    Beal, S.L.3
  • 49
    • 0023954402 scopus 로고
    • Washout time versus mean residence time
    • Weiss M. Washout time versus mean residence time. Pharmazie. 43:1988;126-127.
    • (1988) Pharmazie , vol.43 , pp. 126-127
    • Weiss, M.1
  • 50
    • 0014696582 scopus 로고
    • Occupancy principle: Identity with that of mean transit time of tracers in biological systems
    • Zierler K.L. Occupancy principle: identity with that of mean transit time of tracers in biological systems. Science. 163:1969;491-492.
    • (1969) Science , vol.163 , pp. 491-492
    • Zierler, K.L.1
  • 52
    • 0014982603 scopus 로고
    • Drug-absorption analysis from pharmacological data. I. Method and confirmation exemplified for the mydriatic drug tropicamide
    • Smolen V.F., Schoenwald R.D. Drug-absorption analysis from pharmacological data. I. Method and confirmation exemplified for the mydriatic drug tropicamide. J. Pharm. Sci. 60:1971;96-103.
    • (1971) J. Pharm. Sci. , vol.60 , pp. 96-103
    • Smolen, V.F.1    Schoenwald, R.D.2
  • 53
    • 0023144396 scopus 로고
    • Relative deconvolution. An explicit method for bioavailability comparison not requiring intravenous administration
    • Veng-Pedersen P., Miller R. Relative deconvolution. An explicit method for bioavailability comparison not requiring intravenous administration. Int. J. Clin. Pharmacol. Ther. Toxicol. 25:1987;10-14.
    • (1987) Int. J. Clin. Pharmacol. Ther. Toxicol. , vol.25 , pp. 10-14
    • Veng-Pedersen, P.1    Miller, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.