-
1
-
-
0344188096
-
An adenovirus mutant that replicates selectively in p53-deficient human tumor cells
-
Bischoff JR, Kirn DH, Williams A, et al: An adenovirus mutant that replicates selectively in p53-deficient human tumor cells. Science 274:373-376, 1996
-
(1996)
Science
, vol.274
, pp. 373-376
-
-
Bischoff, J.R.1
Kirn, D.H.2
Williams, A.3
-
2
-
-
12944328660
-
A phase I study of Onyx-015, an E1B attenuated adenovirus, administered intratumorally to patients with recurrent head and neck cancer
-
Ganly I, Kirn D, Eckhardt G, et al: A phase I study of Onyx-015, an E1B attenuated adenovirus, administered intratumorally to patients with recurrent head and neck cancer. Clin Cancer Res 6:798-806, 2000
-
(2000)
Clin Cancer Res
, vol.6
, pp. 798-806
-
-
Ganly, I.1
Kirn, D.2
Eckhardt, G.3
-
3
-
-
0033693231
-
Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: A phase II trial
-
Nemunaitis J, Ganly I, Khuri F, et al: Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: A phase II trial. Cancer Res 60:6359-6366, 2000
-
(2000)
Cancer Res
, vol.60
, pp. 6359-6366
-
-
Nemunaitis, J.1
Ganly, I.2
Khuri, F.3
-
4
-
-
0035863458
-
Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer
-
Nemunaitis J, Khuri F, Ganly I, et al: Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer. J Clin Oncol 19:289-298, 2001
-
(2001)
J Clin Oncol
, vol.19
, pp. 289-298
-
-
Nemunaitis, J.1
Khuri, F.2
Ganly, I.3
-
5
-
-
0033831080
-
-
Khuri FR, Nemunaitis J, Ganly I, et al: a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer. Nat Med 6:879-885, 2000
-
Khuri FR, Nemunaitis J, Ganly I, et al: a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer. Nat Med 6:879-885, 2000
-
-
-
-
6
-
-
0031743945
-
Replication of ONYX-015, a potential anticancer adenovirus, is independent of p53 status in tumor cells
-
Rothmann T, Hengstermann A, Whitaker NJ, et al: Replication of ONYX-015, a potential anticancer adenovirus, is independent of p53 status in tumor cells. J Virol 72:9470-9478, 1998
-
(1998)
J Virol
, vol.72
, pp. 9470-9478
-
-
Rothmann, T.1
Hengstermann, A.2
Whitaker, N.J.3
-
7
-
-
0031697770
-
p53-dependent cell death/apoptosis is required for a productive adenovirus infection
-
Hall AR, Dix BR, O'Carroll SJ, et al: p53-dependent cell death/apoptosis is required for a productive adenovirus infection. Nat Med 4:1068-1072, 1998
-
(1998)
Nat Med
, vol.4
, pp. 1068-1072
-
-
Hall, A.R.1
Dix, B.R.2
O'Carroll, S.J.3
-
8
-
-
0030702841
-
p53/E1b58kDa complex regulates adenovirus replication
-
Ridgway PJ, Hall AR, Myers CJ, et al: p53/E1b58kDa complex regulates adenovirus replication. Virology 237:404-413, 1997
-
(1997)
Virology
, vol.237
, pp. 404-413
-
-
Ridgway, P.J.1
Hall, A.R.2
Myers, C.J.3
-
9
-
-
0034722895
-
ONYX-015 selectivity and the p14ARF pathway
-
McCormick F: ONYX-015 selectivity and the p14ARF pathway. Oncogene 19:6670-6672, 2000
-
(2000)
Oncogene
, vol.19
, pp. 6670-6672
-
-
McCormick, F.1
-
10
-
-
0033623250
-
Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015)
-
Ries SJ, Brandts CH, Chung AS, et al: Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015). Nat Med 6:1128-1133, 2000
-
(2000)
Nat Med
, vol.6
, pp. 1128-1133
-
-
Ries, S.J.1
Brandts, C.H.2
Chung, A.S.3
-
11
-
-
0037087621
-
Phase I trial of intraperitoneal injection of the E1B-55-kd-gene-deleted adenovirus ONYX-015 (dl1520) given on days 1 through 5 every 3 weeks in patients with recurrent/refractory epithelial ovarian cancer
-
Vasey PA, Shulman LN, Campos S, et al: Phase I trial of intraperitoneal injection of the E1B-55-kd-gene-deleted adenovirus ONYX-015 (dl1520) given on days 1 through 5 every 3 weeks in patients with recurrent/refractory epithelial ovarian cancer. J Clin Oncol 20:1562-1569, 2002
-
(2002)
J Clin Oncol
, vol.20
, pp. 1562-1569
-
-
Vasey, P.A.1
Shulman, L.N.2
Campos, S.3
-
12
-
-
0037314655
-
Phase II clinical trial of intralesional administration of the oncolytic adenovirus ONYX-015 in patients with hepatobiliary tumors with correlative p53 studies
-
Makower D, Rozenblit A, Kaufman H, et al: Phase II clinical trial of intralesional administration of the oncolytic adenovirus ONYX-015 in patients with hepatobiliary tumors with correlative p53 studies. Clin Cancer Res 9:693-702, 2003
-
(2003)
Clin Cancer Res
, vol.9
, pp. 693-702
-
-
Makower, D.1
Rozenblit, A.2
Kaufman, H.3
-
13
-
-
0035076823
-
Safety and feasibility of injection with an E1B-55 kDa gene-deleted, replication-selective adenovirus (ONYX-015) into primary carcinomas of the pancreas: A phase I trial
-
Mulvihill S, Warren R, Venook A, et al: Safety and feasibility of injection with an E1B-55 kDa gene-deleted, replication-selective adenovirus (ONYX-015) into primary carcinomas of the pancreas: A phase I trial. Gene Ther 8:308-315, 2001
-
(2001)
Gene Ther
, vol.8
, pp. 308-315
-
-
Mulvihill, S.1
Warren, R.2
Venook, A.3
-
14
-
-
0035177690
-
Intra-arterial administration of a replication-selective adenovirus (dl1520) in patients with colorectal carcinoma metastatic to the liver: A phase I trial
-
Reid T, Galanis E, Abbruzzese J, et al: Intra-arterial administration of a replication-selective adenovirus (dl1520) in patients with colorectal carcinoma metastatic to the liver: A phase I trial. Gene Ther 8:1618-1626, 2001
-
(2001)
Gene Ther
, vol.8
, pp. 1618-1626
-
-
Reid, T.1
Galanis, E.2
Abbruzzese, J.3
-
15
-
-
0345184328
-
-
Sze DY, Freeman SM, Slonim SM, et al: Dr. Gary J. Becker Young Investigator Award: Intraarterial adenovirus for metastatic gastrointestinal cancer-Activity, radiographic response, and survival. J Vasc Interv Radiol 14:279-290, 2003
-
Sze DY, Freeman SM, Slonim SM, et al: Dr. Gary J. Becker Young Investigator Award: Intraarterial adenovirus for metastatic gastrointestinal cancer-Activity, radiographic response, and survival. J Vasc Interv Radiol 14:279-290, 2003
-
-
-
-
16
-
-
1542438707
-
An attenuated adenovirus, ONYX-015, as mouthwash therapy for premalignant oral dysplasia
-
Rudin CM, Cohen EEW, Papadimitrakopoulou VA, et al: An attenuated adenovirus, ONYX-015, as mouthwash therapy for premalignant oral dysplasia. J Clin Oncol 21:4546-4552, 2003
-
(2003)
J Clin Oncol
, vol.21
, pp. 4546-4552
-
-
Rudin, C.M.1
Cohen, E.E.W.2
Papadimitrakopoulou, V.A.3
-
17
-
-
0343091242
-
Predicting cancer development in oral leukoplakia: Ten years of translational research
-
Lee JJ, Hong WK, Hittelman WN, et al: Predicting cancer development in oral leukoplakia: ten years of translational research. Clin Cancer Res 6:1702-1710, 2000
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1702-1710
-
-
Lee, J.J.1
Hong, W.K.2
Hittelman, W.N.3
-
18
-
-
0029835812
-
Photodynamic therapy using 5-aminolevulinic acid for premalignant and malignant lesions of the oral cavity
-
Fan KF, Hopper C, Speight PM, et al: Photodynamic therapy using 5-aminolevulinic acid for premalignant and malignant lesions of the oral cavity. Cancer 78:1374-1383, 1996
-
(1996)
Cancer
, vol.78
, pp. 1374-1383
-
-
Fan, K.F.1
Hopper, C.2
Speight, P.M.3
-
19
-
-
0030119029
-
Photodynamic therapy of oral cancer: A review of basic mechanisms and clinical applications
-
Nauta JM, van Leengoed HL, Star WM, et al: Photodynamic therapy of oral cancer: A review of basic mechanisms and clinical applications. Eur J Oral Sci 104:69-81, 1996
-
(1996)
Eur J Oral Sci
, vol.104
, pp. 69-81
-
-
Nauta, J.M.1
van Leengoed, H.L.2
Star, W.M.3
-
20
-
-
0033063487
-
Laser management of oral leukoplakias: A follow-up study of 70 patients
-
Schoelch ML, Sekandari N, Regezi JA, et al: Laser management of oral leukoplakias: A follow-up study of 70 patients. Laryngoscope 109:949-953, 1999
-
(1999)
Laryngoscope
, vol.109
, pp. 949-953
-
-
Schoelch, M.L.1
Sekandari, N.2
Regezi, J.A.3
-
21
-
-
78651056338
-
Field cancerization in oral stratified squamous epithelium
-
Slaughter D, Southwick H, Smejkal W: Field cancerization in oral stratified squamous epithelium. Cancer 6:963-968, 1953
-
(1953)
Cancer
, vol.6
, pp. 963-968
-
-
Slaughter, D.1
Southwick, H.2
Smejkal, W.3
-
22
-
-
0022916262
-
13-cis-retinoic acid in the treatment of oral leukoplakia
-
Hong WK, Endicott J, Itri LM, et al: 13-cis-retinoic acid in the treatment of oral leukoplakia. N Engl J Med 315:1501-1505, 1986
-
(1986)
N Engl J Med
, vol.315
, pp. 1501-1505
-
-
Hong, W.K.1
Endicott, J.2
Itri, L.M.3
-
23
-
-
0028908858
-
p53 and retinoid chemoprevention of oral carcinogenesis
-
Lippman SM, Shin DM, Lee JJ, et al: p53 and retinoid chemoprevention of oral carcinogenesis. Cancer Res 55:16-19, 1995
-
(1995)
Cancer Res
, vol.55
, pp. 16-19
-
-
Lippman, S.M.1
Shin, D.M.2
Lee, J.J.3
-
24
-
-
0031015942
-
Low-dose isotretinoin versus beta-carotene to prevent oral carcinogenesis: Long-term follow-up
-
Papadimitrakopoulou VA, Hong WK, Lee JS, et al: Low-dose isotretinoin versus beta-carotene to prevent oral carcinogenesis: Long-term follow-up. J Natl Cancer Inst 89:257-258, 1997
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 257-258
-
-
Papadimitrakopoulou, V.A.1
Hong, W.K.2
Lee, J.S.3
-
25
-
-
0031055451
-
Phase I trial of alpha-tocopherol effects on 13-cis-retinoic acid toxicity
-
Dimery IW, Hong WK, Lee JJ, et al: Phase I trial of alpha-tocopherol effects on 13-cis-retinoic acid toxicity. Ann Oncol 8:85-89, 1997
-
(1997)
Ann Oncol
, vol.8
, pp. 85-89
-
-
Dimery, I.W.1
Hong, W.K.2
Lee, J.J.3
-
26
-
-
0030742121
-
Molecular analysis of oral lichen planus: A premalignant lesion?
-
Zhang L, Michelsen C, Cheng X, et al: Molecular analysis of oral lichen planus: A premalignant lesion? Am J Pathol 151:323-327, 1997
-
(1997)
Am J Pathol
, vol.151
, pp. 323-327
-
-
Zhang, L.1
Michelsen, C.2
Cheng, X.3
-
27
-
-
0032077445
-
p53 expression in oral precancer as a marker for malignant potential
-
Murti PR, Warnakulasuriya KA, Johnson NW, et al: p53 expression in oral precancer as a marker for malignant potential. J Oral Pathol Med 27:191-196, 1998
-
(1998)
J Oral Pathol Med
, vol.27
, pp. 191-196
-
-
Murti, P.R.1
Warnakulasuriya, K.A.2
Johnson, N.W.3
-
28
-
-
0028158007
-
Activation of p53 gene expression in premalignant lesions during head and neck tumorigenesis
-
Shin DM, Kim J, Ro JY, et al: Activation of p53 gene expression in premalignant lesions during head and neck tumorigenesis. Cancer Res 54:321-326, 1994
-
(1994)
Cancer Res
, vol.54
, pp. 321-326
-
-
Shin, D.M.1
Kim, J.2
Ro, J.Y.3
-
29
-
-
0030612712
-
Frequent inactivation of p16INK4a in oral premalignant lesions
-
Papadimitrakopoulou V, Izzo J, Lippman SM, et al: Frequent inactivation of p16INK4a in oral premalignant lesions. Oncogene 14:1799-1803, 1997
-
(1997)
Oncogene
, vol.14
, pp. 1799-1803
-
-
Papadimitrakopoulou, V.1
Izzo, J.2
Lippman, S.M.3
|