Synthesis and anticonvulsant activity of novel 1-substituted-1,2-dihydro- pyridazine-3,6-diones

Biological and Pharmaceutical Bulletin

Volumn 26, Issue 10, 2003, Pages 1407-1411

  Sivakumar, Ramaiah ^a   Anbalagan, Navaneetharaman ^b   Gunasekaran, Vedachalam ^a   Leonard, Joseph Thomas ^a  

^a VELS INSTITUTE OF SCIENCE   (India)

^b C L BAID METHA COLLEGE OF PHARMACY   (India)

Author keywords

Aminopropane; Anticonvulsant; Propanolamine; Pyridazine 3,6 dione

Indexed keywords

1 (2 HYDROXY 3 IMIDAZOL 1 YLPROPYL) 1,2 DIHYDROPYRIDAZINE 3,6 DIONE; 1 (2 HYDROXY 3 PIPERAZIN 1 YLPROPYL) 1,2 DIHYDROPYRIDAZINE 3,6 DIONE; 1 (3' DIMETHYLAMINOPROPYL) 1,2 DIHYDROPYRIDAZINE 3,6 DIONE; 1 (3' DIPHENYLAMINOPROPYL) 1,2 DIHYDROPYRIDAZINE 3,6 DIONE; 1 [2' HYDROXY 3' (1'' MORPHOLINO)PROPYL] 1,2 DIHYDROPYRIDAZINE 3,6 DIONE; 1 [2' HYDROXY 3' (1'' PIPERIDINO)PROPYL] 1,2 DIHYDROPYRIDAZINE 3,6 DIONE; 1 [2' HYDROXY 3' (4'' HYDROXYPHENYLAMINO)PROPYL] 1,2 DIHYDROPYRIDAZINE 3,6 DIONE; 1 [2' HYDROXY 3' (4'' NITROPHENYLAMINO)PROPYL] 1,2 DIHYDROPYRIDAZINE 3,6 DIONE; 1 [2' HYDROXY 3' (DIMETHYLAMINO)PROPYL] 1,2 DIHYDROPYRIDAZINE 3,6 DIONE; 1 [2' HYDROXY 3' (DIPHENYLAMINO)PROPYL] 1,2 DIHYDROPYRIDAZINE 3,6 DIONE; 1 [2' HYDROXY 3' (METHYLAMINO)PROPYL] 1,2 DIHYDROPYRIDAZINE 3,6 DIONE; 1 [2' HYDROXY 3' (PHENYLAMINO)PROPYL] 1,2 DIHYDROPYRIDAZINE 3,6 DIONE; 1 [3 (2 AMINOPHENYLAMINO) 2 HYDROXYPROPYL]1,2 DIHYDROPYRIDAZINE 3,6 DIONE; 1 [3' (1 MORPHOLINO)PROPYL] 1,2 DIHYDROPYRIDAZINE 3,6 DIONE; 1 [3' (1'' IMIDAZOLO)PROPYL] 1,2 DIHYDROPYRIDAZINE 3,6 DIONE; 1 [3' (1'' PIPERAZINO)PROPYL] 1,2 DIHYDROPYRIDAZINE 3,6 DIONE; 1 [3' (1'' PIPERIDINO)PROPYL] 1,2 DIHYDROPYRIDAZINE 3,6 DIONE; 1 [3' (2'' AMINOPHENYLAMINO)PROPYL] 1,2 DIHYDROPYRIDAZINE 3,6 DIONE; 1 [3' (4'' NITROPHENYLAMINO)PROPYL] 1,2 DIHYDROPYRIDAZINE 3,6 DIONE; 1 [3' [BIS(2'' HYDROXYETHYL)AMINO] 2 (HYDROXYPROPYL)] 1,2 DIHYDROPYRIDAZINE 3,6 DIONE; ANTICONVULSIVE AGENT; CARBAMAZEPINE; MALEIC HYDRAZIDE; PHENYTOIN; UNCLASSIFIED DRUG; VALPROIC ACID; 1,4 DIHYDROPYRIDINE; 1,4-DIHYDROPYRIDINE; DIHYDROPYRIDINE DERIVATIVE; PYRIDAZINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; BRAIN PROTECTION; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; ELECTRIC SHOCK; MOUSE; NEUROTOXICITY; NONHUMAN; SEIZURE; SUBSTITUTION REACTION; ANIMAL; FEMALE; MALE; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANIMALS; ANTICONVULSANTS; DIHYDROPYRIDINES; FEMALE; MALE; MICE; PYRIDAZINES; SEIZURES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 1542646189     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.26.1407     Document Type: Article

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