Organic solvent-induced proximal tubular cell apoptosis via caspase-9 activation

Environmental Toxicology and Pharmacology

Volumn 16, Issue 3, 2004, Pages 147-152

  Al Ghamdi, Saeed S ^a,b   Raftery, Martin J ^a   Yaqoob, Muhammad M ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b 143A O'Driscoll House ^*  (United Kingdom)

Author keywords

Apoptosis; Bax; Bcl 2; Caspase 9; LLC PK1 cells; p xylene; Toluene

Indexed keywords

BENZYLOXYCARBONYLLEUCYLGLUTAMYLHISTIDYLASPARTYL FLUOROMETHYL KETONE; CASPASE 9; CASPASE INHIBITOR; DNA FRAGMENT; ORGANIC SOLVENT; PARA XYLENE; PROTEIN BAX; PROTEIN BCL 2; TOLUENE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL STRAIN; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME ACTIVITY; KIDNEY PROXIMAL TUBULE; LONG TERM EXPOSURE; NONHUMAN; PRIORITY JOURNAL; UPREGULATION;

EID: 1542613801     PISSN: 13826689     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etap.2003.12.002     Document Type: Article

References (33)

1. Agarwal A., Balla J., Balla G., Croatt A.I., Vercellotti G.M., Nath K.A. Renal tubular epithelial cells mimic endothelial cells upon exposure to oxidized LDL. Am. J. Physiol. 271:1996;F814-F823.
2. Akao Y., Otsuki Y., Kataoka S., Ito Y., Tsujimoto Y. Multiple subcellular localization of Bcl-2: detection in nuclear outer membrane, endoplasmic reticulum membrane, and mitochondrial membranes. Cancer Res. 54:1994;2468-2471.
3. Al-Ghamdi, S.S., Allen, D.A., Raftery, M.J., Yaqoob, M.M., 2001. Solvent-induced activation of CYP2E1 causes proximal tubular apoptosis by oxidative stress. J. Am. Soc. Nephrol. A4168.
4. Al-Ghamdi S.S., Raftery M.J., Yaqoob M.M. Acute solvent exposure induced activation of cytochrome P4502E1 causes proximal tubular cell necrosis by oxidative stress. Toxicol. in Vitro. 17:2003a;335-341.
5. Al-Ghamdi S.S., Raftery M.J., Yaqoob M.M. Organic solvent-induced proximal tubular cell toxicity via caspase-3 activation. J. Toxicol. Clin. Toxicol. 41:2003b;967-971.
6. Ali S.M., Wong V.Y., Kikly K., Fredrickson T.A., Keller P.M., Dewolf J.R., Lee D., Brooks D.P. Apoptosis in polycystic kidney disease: involvement of caspases. Am. J. Physiol. Regul. Integr. Comp. Physiol. 278:2000;R763-R769.
7. Basile D.P., Liapis H., Hammerman M.R. Expression of Bcl-2 and bax in regenerating rat renal tubules following ischemic injury. Am. J. Physiol. 272:1997;F640-F647.
8. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
9. Chang S.H., Phelps P.C., Berezesky I.K., Ebersberger M.L., Trump B.F. Studies on the mechanisms and kinetics of apoptosis induced by microinjection of cytochrome c in rat kidney tubule epithelial cells (NRK-52E). Am. J. Pathol. 156:2000;637-649.
10. Cheng E.H., Kirsch D.G., Clem R.J., Ravi R., Kastan M.B., Bedi A., Ueno K., Hardwick J.M. Conversion of Bcl-2 to a Bax-like death effector by caspases. Science. 278:1997;1966-1968.
11. Chinnaiyan A.M., Orth K., O'Bourke K., Duan H., Poirier G.G., Dixit V.M. Molecular ordering of the cell death pathway. Bcl-2 and Bcl-xL function upstream of the CED-3-like apoptotic proteases. J. Biol. Chem. 271:1996;4573-4576.
12. Conaldi P.G., Biancone L., Bottelli A., Wade-Evans A., Racusen L.C., Boccellino M., Orlandi V., Serra C., Camussi G., Toniolo A. HIV-1 kills renal tubular epithelial cells in vitro by triggering an apoptotic pathway involving caspase activation and Fas up-regulation. J. Clin. Invest. 102:1998;2041-2049.
13. Edelstein C.L., Shi Y., Schrier R.W. Role of caspases in hypoxia-induced necrosis of rat renal proximal tubules. J. Am. Soc. Nephrol. 10:1999;1940-1949.
14. Fukuoka K., Takeda M., Kobayashi M., Osaki T., Shirato I., Soejima A., Nagasawa T., Endou H. Distinct interleukin-1beta-converting enzyme family proteases mediate cis-platin- and staurosporine-induced apoptosis of mouse proximal tubule cells. Life Sci. 62:1998;1125-1138.
15. Gross A., Jockel J., Wei M.C., Korsmeyer S.J. Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis. EMBO J. 17:1998;3878-3885.
16. Kaushal G.P., Singh A.B., Shah S.V. Identification of gene family of caspases in rat kidney and altered expression in ischemia-reperfusion injury. Am. J. Physiol. 274:1998;F587-F595.
17. Kaushal G.P., Kaushal V., Hong X., Shah S.V. Role and regulation of activation of caspases in cis-platin-induced injury to renal tubular epithelial cells. Kidney Int. 60:2001;1726-1736.
18. Kuida K., Haydar T.F., Kuan C.Y., Gu Y., Taya C., Karasuyama H., Su M.S., Rakic P., Flavell R.A. Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9. Cell. 94:1998;325-337.
19. Lau A.H. Apoptosis induced by cis-platin nephrotoxic injury. Kidney Int. 56:1999;1295-1298.
20. Li P., Nijhawan D., Budihardjo I., Srinivasula S.M., Ahmad M., Alnemri E.S., Wang X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell. 91:1997;479-489.
21. Lieberthal W., Triaca V., Koh J.S., Pagano P.J., Levine J.S. Role of superoxide in apoptosis induced by growth factor withdrawal. Am. J. Physiol. 275:1998;F691-F702.
22. Nath K.A., Croatt A.J., Haggard J.J., Grande J.P. Renal response to repetitive exposure to heme proteins: chronic injury induced by an acute insult. Kidney Int. 57:2000;2423-2433.
23. Oltvai Z.N., Korsmeyer S.J. Checkpoints of dueling dimers foil death wishes. Cell. 79:1994;189-192.
24. Ortiz A., Lorz C., Catalan M., Ortiz A., Coca S., Egido J. Cyclosporine A induces apoptosis in murine tubular epithelial cells: role of caspases. Kidney Int. Suppl. 68:1998;S25-S29.
25. Park M.Y., Lee R.H., Lee S.H., Jung J. Apoptosis induced by inhibition of contact with extracellular matrix in mouse collecting duct cells. Nephron. 83:1999;341-351.
26. Park M.S., De Leon M., Devarajan P. Cis-platin induces apoptosis in LLC-PK1 cells via activation of mitochondrial pathways. J. Am. Soc. Nephrol. 13:2002;858-865.
27. Reed J.C. Bcl-2 family proteins. Oncogene. 17:1998;3225-3236.
28. Rudel T. Caspase inhibitors in prevention of apoptosis. Herz. 24:1999;236-241.
29. Saleh A., Srinivasula S.M., Acharya S., Fishel R., Alnemri E.S. Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation. Biol. Chem. 274:1999;17941-17945.
30. Thornberry N.A., Lazebnik Y. Caspases: enemies within. Science. 281:1998;1312-1316.
31. Wang N.S., Unkila M.T., Reineks E.Z., Distelhorst C.W. Transient expression of wild-type or mitochondrially targeted Bcl-2 induces apoptosis, whereas transient expression of endoplasmic reticulum-targeted Bcl-2 is protective against Bax-induced cell death. J. Biol. Chem. 276:2001;44117-44128.
32. Wedeen R.P. Occupational and environmental renal disease. Semin. Nephrol. 17:1997;46-53.
33. Yang B., El-Nahas A.M., Thomas G.L., Haylor J.L., Watson P.F., Wagner B., Johnson T.S. Caspase-3 and apoptosis in experimental chronic renal scarring. Kidney Int. 60:2001;1765-1776.