CagA genotype and variants in Chinese Helicobacter pylori strains and relationship to gastroduodenal diseases

Journal of Medical Microbiology

Volumn 53, Issue 3, 2004, Pages 231-235

  Zhou, Jianchang ^a,b   Zhang, Jianzhong ^a   Xu, Caipu ^b   He, Lihua ^a  

^a CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATE; BACTERIUM ISOLATION; CHINESE; CHRONIC GASTRITIS; CONTROLLED STUDY; DISEASE ASSOCIATION; DUODENUM DISEASE; GENETIC CODE; GENETIC VARIABILITY; GENOTYPE; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; NONHUMAN; PEPTIC ULCER; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STOMACH CANCER; STOMACH DISEASE;

ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CHINA; DNA, BACTERIAL; ELECTROPHORESIS, AGAR GEL; GASTRITIS; GENOTYPE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; PEPTIC ULCER; POLYMERASE CHAIN REACTION; STOMACH NEOPLASMS;

EID: 1542509782     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/jmm.0.05366-0     Document Type: Article

References (25)

1. Abasiyanik, M. F., Sander, E. & Salih, B. A. (2002). Helicobacter pylori anti-CagA antibodies: prevalence in symptomatic and asymptomatic subjects in Turkey. Can J Gastroenterol 16, 527-532.
2. Andreson, H., Lōivukene, K., Sillakivi, T., Maaroos, H.-I., Ustav, M., Peetsalu, A. & Mikelsaar, M. (2002). Association of cagA and vacA genotypes of Helicobacter pylori with gastric diseases in Estonia. J Clin Microbiol 40, 298-300.
3. Azuma, T., Yamakawa, A., Yamazaki, S., Fukuta, K., Ohtani, M., Ito, Y., Dojo, M., Yamazaki, Y. & Kuriyama, M. (2002). Correlation between variation of the 3′ region of the cagA gene in Helicobacter pylori and disease outcome in Japan. J Infect Dis 186, 1621-1630.
4. Bach, S., Makristathis, A., Pinto, A., Quina, M., Rotter, M. & Hirschl, A. M. (1999). Helicobacter pylori type I strains among Austrian and Portuguese patients with gastritis, peptic ulcer or gastric cancer. Eur J Clin Microbiol Infect Dis 18, 807-810.
5. Blaser, M. J., Pérez-Pérez, G. I., Kleanthous, H., Cover, T. L., Peek, R. M., Chyou, P. H., Stemmermann, G. N. & Nomura, A. (1995). Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach. Cancer Res 55, 2111-2115.
6. Catalano, M., Matteo, M., Barbolla, R. E., Jimenez Vega, D. E., Crespo, O., Leanza, A. G., Toppor, J. & Antelo, P. (2001). Helicobacter pylori vacA genotypes, cagA status and ureA-B polymorphism in isolates recovered from an Argentine population. Diagn Microbiol Infect Dis 41, 205-210.
7. Covacci, A., Censini, S., Bugnoli, M. & 8 other authors (1993). Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer. Proc Natl Acad Sci U S A 90, 5791-5795.
8. Groves, F. D., Pérez-Pérez, G., Zhang, L., You, W.-C., Lipsitz, S. R., Gail, M. H., Fraumeni, J. F., Jr & Blaser, M. J. (2002). Serum antibodies to Helicobacter pylori and the CagA antigen do not explain differences in the prevalence of precancerous gastric lesions in two Chinese populations with contrasting gastric cancer rates. Cancer Epidemiol Biomarkers Prev 11, 1091-1094.
9. Kidd, M., Lastovica, A. J., Atherton, J. C. & Louw, J. A. (1999). Heterogeneity in the Helicobacter pylori vacA and cagA genes: association with gastroduodenal disease in South Africa? Gut 45, 499-502.
10. Lai, C.-H., Kuo, C.-H., Chen, Y.-C., Chao, F.-Y., Poon, S.-K., Chang, C.-S. & Wang, W.-C. (2002). High prevalence of cagA- and babA2-positive Helicobacter pylori clinical isolates in Taiwan. J Clin Microbiol 40, 3860-3862.
11. Maeda, S., Ogura, K., Yoshida, H., Kanai, F., Ikenoue, T., Kato, N., Shiratori, Y. & Omata, M. (1998). Major virulence factors, VacA and CagA, are commonly positive in Helicobacter pylori isolates in Japan. Gut 42, 338-343.
12. Miehlke, S., Kibler, K., Kim, J. G., Figura, N., Small, S. M., Graham, D. Y. & Go, M. F. (1996). Allelic variation in the cagA gene of Helicobacter pylori obtained from Korea compared to the United States. Am J Gastroenterol 91, 1322-1325.
13. Miehlke, S., Kirsch, C., Agha-Amiri, K., Günther, T., Lehn, N., Malfertheiner, P., Stolte, M., Ehninger, G. & Bayerdörffer, E. (2000). The Helicobacter pylori vacA s1, m1 genotype and cagA is associated with gastric carcinoma in Germany. Int J Cancer 87, 322-327.
14. Nomura, A. M., Pérez-Pérez, G. I., Lee, J., Stemmermann, G. & Blaser, M. J. (2002a). Relation between Helicobacter pylori cagA status and risk of peptic ulcer disease. Am J Epidemiol 155, 1054-1059.
15. Nomura, A. M., Lee, J., Stemmermann, G. N., Nomura, R. Y., Pérez-Pérez, G. I. & Blaser, M. J. (2002b). Helicobacter pylori CagA seropositivity and gastric carcinoma risk in a Japanese American population. J Infect Dis 186, 1138-1144.
16. Oliveira, A. G., Santos, A., Guerra, J. B., Rocha, G. A., Rocha, A. M., Oliveira, C. A., Cabral, M. M., Nogueira, A. M. & Queiroz, D. M. (2003). babA2- and cagA-positive Helicobacter pylori strains are associated with duodenal ulcer and gastric carcinoma in Brazil. J Clin Microbiol 41, 3964-3966.
17. Pan, Z.-J., van der Hulst, R.W. M., Feller, M., Xiao, S.-D., Tytgat, G. N. J., Dankert, J. & van der Ende, A. (1997). Equally high prevalences of infection with cagA-positive Helicobacter pylori in Chinese patients with peptic ulcer disease and those with chronic gastritis-associated dyspepsia. J Clin Microbiol 35, 1344-1347.
18. Rota, C. A., Pereira-Lima, J. C., Blaya, C. & Nardi, N. B. (2001). Consensus and variable region PCR analysis of Helicobacter pylori 3′ region of cagA gene in isolates from individuals with or without peptic ulcer. J Clin Microbiol 39, 606-612.
19. Rudi, J., Kolb, C., Maiwald, M., Kuck, D., Sieg, A., Galle, P. R. & Stremmel, W. (1998). Diversity of Helicobacter pylori vacA and cagA genes and relationship to VacA and CagA protein expression, cytotoxin production, and associated diseases. J Clin Microbiol 36, 944-948.
20. Shimoyama, T., Fukuda, S., Tanaka, M., Mikami, T., Saito, Y. & Munakata, A. (1997). High prevalence of the cagA-positive Helicobacter pylori strains in Japanese asymptomatic patients and gastric cancer patients. Scand J Gastroenterol 32, 465-468.
21. + Helicobacter pylori strains as a possible predictor of risk in the development of gastric adenocarcinoma in Mexico. Int J Cancer 78, 298-300.
22. + strains and risk of adenocarcinoma of the stomach and esophagus. Int J Cancer 103, 815-821.
23. Yamaoka, Y., Kodama, T., Kashima, K., Graham, D. Y. & Sepulveda, A. R. (1998). Variants of the 3′ region of the cagA gene in Helicobacter pylori isolates from patients with different H. pylori-associated diseases. J Clin Microbiol 36, 2258-2263.
24. Yamaoka, Y., El-Zimaity, H. M. T., Gutierrez, O., Figura, N., Kim, J. K., Kodama, T., Kashima, K. & Graham, D. Y. (1999). Relationship between the cagA 3′ repeat region of Helicobacter pylori, gastric histology, and susceptibility to low pH. Gastroenterology 117, 342-349.
25. Zheng, P. Y., Hua, J., Yeoh, K. G. & Ho, B. (2000). Association of peptic ulcer with increased expression of Lewis antigens but not cagA, iceA, and vacA in Helicobacter pylori isolates in an Asian population. Gut 47, 18-22.