Progressive multifocal leukoencephalopathy successfully treated with highly active antiretroviral therapy and cidofovir in an adolescent infected with perinatal human immunodeficiency virus (HIV)

Journal of Child Neurology

Volumn 19, Issue 1, 2004, Pages 35-38

  Robinson, Lisa Gayne ^a,b   Chiriboga, Claudia A ^b,c   Champion, Susan E ^a,b   Ainyette, Ivan ^a,b   Abrams, Elaine J ^a,b  

^a Columbia University ^*  (United States)

^b HARLEM HOSPITAL CENTER   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; CIDOFOVIR; DIDANOSINE; LAMIVUDINE; LOPINAVIR; NEVIRAPINE; PROBENECID; RITONAVIR; STAVUDINE; ZIDOVUDINE;

ADOLESCENT; AMNESIA; ARTICLE; ATAXIA; CASE REPORT; CLINICAL FEATURE; DEMYELINATING DISEASE; DISORIENTATION; DOSE RESPONSE; DYSARTHRIA; FACIAL NERVE PARALYSIS; HEMIPARESIS; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE DEFICIENCY; JC VIRUS; LABORATORY TEST; LEUKOENCEPHALOPATHY; MALE; MORBIDITY; MORTALITY; NUCLEAR MAGNETIC RESONANCE IMAGING; PERINATAL INFECTION; PRIORITY JOURNAL; TREATMENT OUTCOME;

EID: 1542498696     PISSN: 08830738     EISSN: None     Source Type: Journal    
DOI: 10.1177/088307380401900107011     Document Type: Article

References (17)

1. Astrom K, Mancall E, Richardson EJ: Progressive multifocal leukoencephalopathy. Brain 1958;81:93-127.
2. Berger J, Chauhan A, Galey D, Nath A: Epidemiological evidence and molecular basis of interactions between HIV and JC virus. J Neurovirol 2001;7:329-338.
3. Padgett BL, Walker DL, ZuRhein GM, et al: Cultivation of papova-like virus from human brain with progressive multifocal leucoencephalopathy. Lancet 1971;1:1257-1260.
4. Whiteman ML, Post MJ, Berger JR, et al: Progressive multifocal leukoencephalopathy in 47 HIV-seropositive patients: Neuroimaging with clinical and pathologic correlation. Radiology 1993;187:233-240.
5. Berger JR, Major EO: Progressive multifocal leukoencephalopathy. Semin Neurol 1999;19:193-200.
6. Albrecht H, Hoffman C, Degen O, et al: Highly active antiretroviral therapy significantly improves the prognosis of patients with HIV-associated progressive multifocal leukoencephalopathy. AIDS 1998;12:1149-1154.
7. Miralles P, Berenguer J, García de Viedma, D, et al: Treatment of AIDS-associated progressive multifocal leukoencephalopathy with highly active antiretroviral therapy. AIDS 1998;12:2467-2472.
8. Shapiro R, Mullane K, Camras L, et al: Clinical and magnetic resonance imaging regression of progression multifocal leukoencephalopathy in an AIDS patient after intensive antiretroviral therapy. J Neuroimaging 2001;11:336-339.
9. Pasquier R, Clark K, Smith P, et al: JCV-specific cellular immune response correlates with a favorable clinical outcome in HIV-infected individuals with progressive multifocal leukoencephalopathy. J Neurovirol 2001;7:318-322.
10. De Luca A, Giancola M, Ammassari A, et al: Cidofovir added to HAART improves virological and clinical outcome in AIDS-associated progressive multifocal leukoencepahaopathy. AIDS 2000;14:117-121.
11. Razonable R, Aksamit A, Wright A, Wilson J: Cidofovir treatment of progressive multifocal leukoencephalopathy in a patient receiving highly active antiretroviral therapy. Mayo Clin Proc 2001;76:1171-1175.
12. Gasnault J, Kousignian P, Kahraman M, et al: Cidofovir in AIDS-associated progressive multifocal leukoencephalopathy: A monocenter observational study with clinical and JC virus load monitoring. J Neurovirol 2001;7:375-381.
13. Berger JR, Levy RM, Flomenhoft D, Dobbs M: Predictive factors for prolonged survival in acquired immunodeficiency syndrome-associated progressive multifocal leukoencephalopathy. Ann Neurol 1998;44:341-349.
14. Taoufik Y, Delfraissy J, Gasnault J: Highly active antiretroviral therapy does not improve survival of patients with high JC virus load in the cerebrospinal fluid at progressive multifocal leukoencephalopathy diagnosis. AIDS 2000;14:758-759.
15. Berger JR, Scott G, Albrecht J, et al: Progressive multifocal leukoencephalopathy in HIV-1-infected children. AIDS 1992;6:837-841.
16. Vandersteenhoven JJ, Dbaibo G, Boyko OB, et al: Progressive multifocal leukoencephalopathy in pediatric acquired immunodeficiency syndrome. Pediatr Infect Dis J 1992;11:232-237.
17. Hugonenq C, Lethel V, Chambost H, et al: Progressive multifocal leukoencepahalopy revealing AIDS in a 13-year-old girl. Arch Pediatr 2002;9:32-35.