Neurotensin-induced hypothermia improves neurologic outcome after hypoxic-ischemia

Critical Care Medicine

Volumn 32, Issue 3, 2004, Pages 806-810

  Katz, Laurence M ^a   Young, Amanda ^b   Frank, Jonathan E ^a   Wang, Yuanfan ^a   Park, Kyunam ^c  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b MAINE MEDICAL CENTER   (United States)

^c The Catholic University of Korea   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROTENSIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPHYXIA; BODY TEMPERATURE; CONTROLLED STUDY; COOLING; HYPOTHERMIA; HYPOXIA; ISCHEMIA; LATENT PERIOD; MAZE TEST; NEAR DROWNING; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ASPHYXIA; DISEASE MODELS, ANIMAL; HEART ARREST; HYPOTHERMIA, INDUCED; HYPOXIA, BRAIN; NEAR DROWNING; NEUROTENSIN; RANDOM ALLOCATION; RATS; STATISTICS, NONPARAMETRIC;

EID: 1542405051     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000114998.00860.FD     Document Type: Article

References (40)

1. Zhang ZG, Chopp M, Chen H: Duration dependent post-ischemic hypothermia alleviates cortical damage after transient middle cerebral artery occlusion in the rat. J Neurol Sci 1993; 117:240-244
2. Colbourne F, Corbett D: Delayed postischemic hypothermia: A six month survival study using behavioral and histological assessments of neuroprotection. J Neurosci 1995; 15:7250-7260
3. Yanamoto H, Hong SC, Soleau S, et al: Mild postischemic hypothermia limits cerebral injury following transient focal ischemia in rat neocortex. Brain Res 1996; 718:207-211
4. Sterz F, Zeiner A, Kurkciyan I, et al: Mild resuscitative hypothermia and outcome after cardiopulmonary resuscitation. J Neurosurg Anesthesiol 1996; 8:88-96
5. Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. N Engl J Med 2002; 346:549-556
6. Bernard SA, Gray TW, Buist MD, et al: Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. N Engl J Med 2002; 346:557-563
7. Gordon CJ: The therapeutic potential of regulated hypothermia. Emerg Med J 2001; 18:81-89
8. Kuboyama K, Safar P, Radovsky A, et al: Delay in cooling negates the beneficial effect of mild resuscitative cerebral hypothermia after cardiac arrest in dogs: A prospective, randomized study. Crit Care Med 1993; 21:1348-1358
9. Shiomi H, Tamura Y: Pharmacological aspects of mammalian hibernation: Central thermoregulation factors in hibernation cycle. Nippon Yakurigaku Zasshi 2000; 116:304-312
10. Heldmaier G, Ruf T: Body temperature and metabolic rate during natural hypothermia in endotherms. J Comp Physiol [B] 1992; 162:696-706
11. Frerichs KU, Hallenbeck JM: Hibernation in ground squirrels induces state and species-specific tolerance to hypoxia and aglycemia: An in vitro study in hippocampal slices. J Cereb Blood Flow Metab 1998; 18:168-175
12. Aloia RC, Raison JK: Membrane function in mammalian hibernation. Biochim Biophys Acta 1989; 988:123-146
13. Gordon CJ: A review of terms for regulated vs. forced, neurochemical-induced changes in body temperature. Life Sci 1983; 32:1285-1295
14. Muchlinski AE, Ho FJ, Chew P, et al: The concentrations of four neuropeptides in various brain areas of summer active and hibernating Spermophilus lateralis. Comp Biochem Physiol C 1983; 74:185-189
15. Yamada M, Cho T, Coleman NJ, et al: Regulation of daily rhythm of body temperature by neurotensin receptor in rats. Res Commun Mol Pathol Pharmacol 1995; 87:323-332
16. Le F, Cusack B, Richelson E: The neurotensin receptor: Is there more than one subtype? Trends Pharmacol Sci 1996; 17:1-3
17. Tyler BM, Cusack B, Douglas CL, et al: Evidence for additional neurotensin receptor subtypes: Neurotensin analogs that distinguish between neurotensin-mediated hypothermia and antinociception. Brain Res 1998; 792:246-252
18. Tyler BM, Douglas CL, Fauq A, et al: In vitro binding and CNS effects of novel neurotensin agonists that cross the blood-brain barrier. Neuropharmacology 1999; 38:1027-1034
19. Modell JH: Near drowning. Circulation. 1986; 74:IV27-IV28
20. Biagas K: Hypoxic-ischemic brain injury: Advancements in the understanding of mechanisms and potential avenues for therapy. Curr Opin Pediatr 1999; 11:223-228
21. Vaagenes P, Safar P, Moossy J, et al: Asphyxiation versus ventricular fibrillation cardiac arrest in dogs. Differences in cerebral resuscitation effects - a preliminary study. Resuscitation 1997; 35:41-52
22. Vaagenes P: Drowning - near drowning. Tidsskr Nor Laegeforen 1993; 113:2699-2701
23. Katz L, Ebmeyer U, Safar P, et al: Outcome model of asphyxial cardiac arrest in rats. J Cereb Blood Flow Metab 1995; 15:1032-1039
24. McMahon BM, Mays D, Lipsky J, et al: Pharmacokinetics and tissue distribution of a peptide nucleic acid after intravenous administration. Antisense Nucleic Acid Drug Dev 2002; 12:65-70
25. Morris RG, Garrud P, Rawlins JN, et al: Place navigation impaired in rats with hippocampal lesions. Nature 1982; 297:681-683
26. Radovsky A, Katz L, Ebmeyer U, et al: Ischemic neurons in rat brains after 6, 8, or 10 minutes of transient hypoxic ischemia. Toxicol Pathol 1997; 25:500-505
27. Kinney HC, Korein J, Panigrahy A, et al: Neuropathological findings in the brain of Karen Ann Quinlan. The role of the thalamus in the persistent vegetative state. N Engl J Med 1994; 330:1469-1475
28. Frank SM, Higgins MS, Fleisher LA, et al: Adrenergic, respiratory, and cardiovascular effects of core cooling in humans. Am J Physiol 1997; 272:R557-R562
29. Sapolsky RM, Pulsinelli WA: Glucocorticoids potentiate ischemic injury to neurons: Therapeutic implications. Science 1985; 229:1397-1400
30. Neumar RW, Bircher NG, Sim KM, et al: Epinephrine and sodium bicarbonate during CPR following asphyxiai cardiac arrest in rats. Resuscitation 1995; 29:249-263
31. Ginsberg MD: Adventures in the pathophysiology of brain ischemia: Penumbra, gene expression, neuroprotection: The 2002 Thomas Willis Lecture. Stroke 2003; 34:214-223
32. Clifton GL, Miller ER, Choi SC, et al: Lack of effect of induction of hypothermia after acute brain injury. N Engl J Med 2001; 344:556-563
33. Safar PJ, Kochanek PM: Therapeutic hypothermia after cardiac arrest. N Engl J Med 2002; 346:612-613
34. Callaway CW, Tadler SC, Katz LM, et al: Feasibility of external cranial cooling during out-of-hospital cardiac arrest. Resuscitation 2002; 52:159-165
35. Georgiadis D, Schwarz S, Kollmar R, et al: Endovascular cooling for moderate hypothermia in patients with acute stroke: First results of a novel approach. Stroke 2001; 32:2550-2553
36. Kim Y, Busto R, Dietrich WD, et al: Delayed postischemic hyperthermia in awake rats worsens the histopathological outcome of transient focal cerebral ischemia. Stroke 1996; 27:2274-2281
37. Katz LM, Wang Y, McMahon B, et al: Neurotensin analog NT69L induces rapid and prolonged hypothermia after hypoxic ischemia. Acad Emerg Med 2001; 8:1115-1121
38. Kerouac R, St-Pierre S, Manning M, et al: Partial blockade of neurotensin-induced hypotension in rats by nephrectomy captopril and saralasin. Possible mechanisms. Neuropeptides 1983; 3:295-307
39. Wallis RA, Panizzon KL: Protection from hypoxic and N-methyl-D-aspartate injury with azelastine, a leukotriene inhibitor. Eur J Pharmacol 1993; 238:165-171
40. Randomized clinical study of thiopental loading in comatose survivors of cardiac arrest. Brain Resuscitation Clinical Trial I Study Group. N Engl J Med 1986; 314:397-403