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Volumn 15, Issue 2, 2004, Pages 113-118

SR31747A: A peripheral σ ligand with potent antitumor activities

Author keywords

Antitumor effect; Breast cancer; Prostate cancer; SR31747A; Transcriptome; ligand

Indexed keywords

ANTINEOPLASTIC AGENT; CYTOKINE; FLUTAMIDE; LIGAND; LIPOPOLYSACCHARIDE; N CYCLOHEXYL N ETHYL 3 (3 CHLORO 4 CYCLOHEXYLPHENYL) 2 PROPENYLAMINE; N CYCLOHEXYL N ETHYL 3 (3 CHLORO 4 CYCLOHEXYLPHENYL)PROPEN 2 YLAMINE; STAPHYLOCOCCUS ENTEROTOXIN B; UNCLASSIFIED DRUG;

EID: 1542358940     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001813-200402000-00003     Document Type: Review
Times cited : (20)

References (27)
  • 1
    • 0028303659 scopus 로고
    • Allosteric modulation of peripheral σ binding sites by a new selective ligand: SR 31747
    • Paul R, Lavastre S, Floutard D, Floutard R, Canat X, Casellas P, et al. Allosteric modulation of peripheral σ binding sites by a new selective ligand: SR 31747. J Neuroimmunol 1994; 52:183-192.
    • (1994) J Neuroimmunol , vol.52 , pp. 183-192
    • Paul, R.1    Lavastre, S.2    Floutard, D.3    Floutard, R.4    Canat, X.5    Casellas, P.6
  • 2
    • 0028337224 scopus 로고
    • Immunopharmacological profile of SR 31747: In vitro and in vivo studies on humoral and cellular responses
    • Casellas P, Bourrie B, Canat X, Carayon P, Buisson I, Paul R, et al. Immunopharmacological profile of SR 31747: in vitro and in vivo studies on humoral and cellular responses. J Neuroimmunol 1994; 52:193-203.
    • (1994) J Neuroimmunol , vol.52 , pp. 193-203
    • Casellas, P.1    Bourrie, B.2    Canat, X.3    Carayon, P.4    Buisson, I.5    Paul, R.6
  • 4
    • 0028822294 scopus 로고
    • The σ ligand SR 31747 prevents the development of acute graft-versus-host disease in mice by blocking IFN-gamma and GM-CSF mRNA expression
    • Carayon P, Bouaboula M, Loubet JF, Bourne B, Petitpretre G, Le Fur G, et al. The σ ligand SR 31747 prevents the development of acute graft-versus-host disease in mice by blocking IFN-gamma and GM-CSF mRNA expression. Int J Immunopharmacol 1995; 17:753-761.
    • (1995) Int J Immunopharmacol , vol.17 , pp. 753-761
    • Carayon, P.1    Bouaboula, M.2    Loubet, J.F.3    Bourne, B.4    Petitpretre, G.5    Le Fur, G.6
  • 5
    • 0028853342 scopus 로고
    • In vivo inhibition of endotoxin-induced pro-inflammatory cytokines production by the σ ligand SR 31747
    • Derocq JM, Bourrie B, Segui M, Le Fur G, Casellas P. In vivo inhibition of endotoxin-induced pro-inflammatory cytokines production by the σ ligand SR 31747. J Pharmacol Exp Ther 1995; 272:224-230.
    • (1995) J Pharmacol Exp Ther , vol.272 , pp. 224-230
    • Derocq, J.M.1    Bourrie, B.2    Segui, M.3    Le Fur, G.4    Casellas, P.5
  • 6
    • 0030015149 scopus 로고    scopus 로고
    • A σ ligand, SR 31747A, potently modulates Staphylococcal enterotoxin B-induced cytokine production in mice
    • Bourrie B, Benoit JM, Derocq JM, Esclangon M, Thomas C, Le Fur G, et al. A σ ligand, SR 31747A, potently modulates Staphylococcal enterotoxin B-induced cytokine production in mice. Immunology 1996; 88:389-393.
    • (1996) Immunology , vol.88 , pp. 389-393
    • Bourrie, B.1    Benoit, J.M.2    Derocq, J.M.3    Esclangon, M.4    Thomas, C.5    Le Fur, G.6
  • 8
    • 15644367094 scopus 로고    scopus 로고
    • Antiproliferative effects of SR31747A in animal cell lines are mediated by inhibition of cholesterol biosynthesis at the sterol isomerase step
    • Labit-Le Bouteiller C, Jamme MF, David M, Silve S, Lanau C, Dhers C, et al. Antiproliferative effects of SR31747A in animal cell lines are mediated by inhibition of cholesterol biosynthesis at the sterol isomerase step. Eur J Biochem 1998; 256:342-349.
    • (1998) Eur J Biochem , vol.256 , pp. 342-349
    • Labit-Le Bouteiller, C.1    Jamme, M.F.2    David, M.3    Silve, S.4    Lanau, C.5    Dhers, C.6
  • 9
    • 0037428705 scopus 로고    scopus 로고
    • SR31747A is a σ receptor ligand exhibiting antitumoural activity both in vitro and in vivo
    • Berthois Y, Bourrie B, Galiegue S, Vidal H, Carayon P, Martin PM, et al. SR31747A is a σ receptor ligand exhibiting antitumoural activity both in vitro and in vivo. Br J Cancer 2003; 88:438-446.
    • (2003) Br J Cancer , vol.88 , pp. 438-446
    • Berthois, Y.1    Bourrie, B.2    Galiegue, S.3    Vidal, H.4    Carayon, P.5    Martin, P.M.6
  • 10
    • 0028180570 scopus 로고
    • Rat liver and kidney contain high densities of σ and σ receptors: Characterization by ligand binding and photoaffinity labeling
    • Hellewell SB, Bruce A, Feinstein G, Orringer J, Williams W, Bowen WD. Rat liver and kidney contain high densities of σ and σ receptors: characterization by ligand binding and photoaffinity labeling. Eur J Pharmacol 1994; 268:9-18.
    • (1994) Eur J Pharmacol , vol.268 , pp. 9-18
    • Hellewell, S.B.1    Bruce, A.2    Feinstein, G.3    Orringer, J.4    Williams, W.5    Bowen, W.D.6
  • 11
    • 0030800651 scopus 로고    scopus 로고
    • Purification and characterization of the human SR 31747A binding protein. A nuclear membrane protein related to yeast sterol isomerase
    • Jbilo O, Vidal H, Paul R, De Nys N, Bensaid M, Silve S, et al. Purification and characterization of the human SR 31747A binding protein. A nuclear membrane protein related to yeast sterol isomerase. J Biol Chem 1997; 272:27107-27115.
    • (1997) J Biol Chem , vol.272 , pp. 27107-27115
    • Jbilo, O.1    Vidal, H.2    Paul, R.3    De Nys, N.4    Bensaid, M.5    Silve, S.6
  • 13
    • 9544223310 scopus 로고    scopus 로고
    • Emopamil binding protein, a mammalian protein that binds a series of structurally diverse neuroprotective agents, exhibits delta8-delta7 sterol isomerase activity in yeast
    • Silve S, Dupuy PH, Labit-Lebouteiller C, Kaghad M, Chalon P, Rahier A, et al. Emopamil binding protein, a mammalian protein that binds a series of structurally diverse neuroprotective agents, exhibits delta8-delta7 sterol isomerase activity in yeast. J Biol Chem 1996; 271:22434-22440.
    • (1996) J Biol Chem , vol.271 , pp. 22434-22440
    • Silve, S.1    Dupuy, P.H.2    Labit-Lebouteiller, C.3    Kaghad, M.4    Chalon, P.5    Rahier, A.6
  • 14
    • 0033565860 scopus 로고    scopus 로고
    • Colocalization of sterol isomerase and σ(1) receptor at endoplasmic reticulum and nuclear envelope level
    • Dussossoy D, Carayon P, Belugou S, Feraut D, Bord A, Goubet C, et al. Colocalization of sterol isomerase and σ(1) receptor at endoplasmic reticulum and nuclear envelope level. Eur J Biochem 1999; 263:377-386.
    • (1999) Eur J Biochem , vol.263 , pp. 377-386
    • Dussossoy, D.1    Carayon, P.2    Belugou, S.3    Feraut, D.4    Bord, A.5    Goubet, C.6
  • 16
    • 7144259069 scopus 로고    scopus 로고
    • Both the immunosuppressant SR31747 and the antiestrogen tamoxifen bind to an emopamil-insensitive site of mammalian delta8-delta7 sterol isomerase
    • Paul R, Silve S, De Nys N, Dupuy PH, Bouteiller CL, Rosenfeld J, et al. Both the immunosuppressant SR31747 and the antiestrogen tamoxifen bind to an emopamil-insensitive site of mammalian delta8-delta7 sterol isomerase. J Pharmacol Exp Ther 1998; 285:1296-302.
    • (1998) J Pharmacol Exp Ther , vol.285 , pp. 1296-1302
    • Paul, R.1    Silve, S.2    De Nys, N.3    Dupuy, P.H.4    Bouteiller, C.L.5    Rosenfeld, J.6
  • 17
    • 0042440982 scopus 로고    scopus 로고
    • Identification and pharmacological characterization of SRBP-2: A novel SR31747A binding protein
    • Vidal H, Mondesert G, Galiegue S, Carriere D, Dupuy PH, Carayon P, et al. Identification and pharmacological characterization of SRBP-2: a novel SR31747A binding protein. Cancer Res 2003; 63:4809-4818.
    • (2003) Cancer Res , vol.63 , pp. 4809-4818
    • Vidal, H.1    Mondesert, G.2    Galiegue, S.3    Carriere, D.4    Dupuy, P.H.5    Carayon, P.6
  • 18
    • 0042827748 scopus 로고    scopus 로고
    • Cloning of an emopamil binding protein (EBP)-like protein that lacks sterol delta8-delta7 isomerase activity
    • Moebius FF, Fitzky BU, Wietzorrek G, Haidekker A, Eder A, Glossmann H. Cloning of an emopamil binding protein (EBP)-like protein that lacks sterol delta8-delta7 isomerase activity. Biochem J 2003; 374:229-237.
    • (2003) Biochem J , vol.374 , pp. 229-237
    • Moebius, F.F.1    Fitzky, B.U.2    Wietzorrek, G.3    Haidekker, A.4    Eder, A.5    Glossmann, H.6
  • 19
    • 0030949390 scopus 로고    scopus 로고
    • The mysteries of σ receptors: New family members reveal a role in cholesterol synthesis
    • Moebius FF, Striessnig J, Glossmann H. The mysteries of σ receptors: new family members reveal a role in cholesterol synthesis. Trends Pharmacol Sci 1997; 18:67-70.
    • (1997) Trends Pharmacol Sci , vol.18 , pp. 67-70
    • Moebius, F.F.1    Striessnig, J.2    Glossmann, H.3
  • 20
    • 0024518488 scopus 로고
    • Sigma-receptors in endocrine organs: Identification, characterization, and autoradiographic localization in rat pituitary, adrenal, testis, and ovary
    • Wolfe SA Jr, Culp SG, De Souza EB. Sigma-receptors in endocrine organs: identification, characterization, and autoradiographic localization in rat pituitary, adrenal, testis, and ovary. Endocrinology 1989; 124:1160-1172.
    • (1989) Endocrinology , vol.124 , pp. 1160-1172
    • Wolfe Jr., S.A.1    Culp, S.G.2    De Souza, E.B.3
  • 22
    • 0028795145 scopus 로고
    • Sigma-1 and σ-2 receptors are expressed in a wide variety of human and rodent tumor cell lines
    • Vilner BJ, John CS, Bowen WD. Sigma-1 and σ-2 receptors are expressed in a wide variety of human and rodent tumor cell lines. Cancer Res 1995; 55:408-413.
    • (1995) Cancer Res , vol.55 , pp. 408-413
    • Vilner, B.J.1    John, C.S.2    Bowen, W.D.3
  • 23
    • 0034071092 scopus 로고    scopus 로고
    • Immunocytochemical assessment of σ-1 receptor and human sterol isomerase in breast cancer and their relationship with a series of prognostic factors
    • Simony-Lafontaine J, Esslimani M, Bribes E, Gourgou S, Lequeux N, Lavail R, et al. Immunocytochemical assessment of σ-1 receptor and human sterol isomerase in breast cancer and their relationship with a series of prognostic factors. Br J Cancer 2000; 82:1958-1966.
    • (2000) Br J Cancer , vol.82 , pp. 1958-1966
    • Simony-Lafontaine, J.1    Esslimani, M.2    Bribes, E.3    Gourgou, S.4    Lequeux, N.5    Lavail, R.6
  • 26
    • 0036426972 scopus 로고    scopus 로고
    • A DNA microarray-based approach to elucidate the effects of the immunosuppressant SR31747A on gene expression in Saccharomyces cerevisiae
    • Cinato E, Peleraux A, Silve S, Galiegue S, Dhers C, Picard C, et al. A DNA microarray-based approach to elucidate the effects of the immunosuppressant SR31747A on gene expression in Saccharomyces cerevisiae. Gene Expr 2002; 10:213-230.
    • (2002) Gene Expr , vol.10 , pp. 213-230
    • Cinato, E.1    Peleraux, A.2    Silve, S.3    Galiegue, S.4    Dhers, C.5    Picard, C.6
  • 27
    • 0345602160 scopus 로고    scopus 로고
    • Transcriptomic classification of antitumor molecules: Application for molecular analysis of the antitumoral effect of SR31747A
    • in press
    • Ferrini JB, Jbilo O, Peleraux A, Combes T, Vidal H, Galiegue S, et al. Transcriptomic classification of antitumor molecules: application for molecular analysis of the antitumoral effect of SR31747A. Gene Expr 2003; in press.
    • (2003) Gene Expr
    • Ferrini, J.B.1    Jbilo, O.2    Peleraux, A.3    Combes, T.4    Vidal, H.5    Galiegue, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.