Antiproliferative effects of SR31747A in animal cell lines are mediated by inhibition of cholesterol biosynthesis at the sterol isomerase step

European Journal of Biochemistry

Volumn 256, Issue 2, 1998, Pages 342-349

  Labit Le Bouteiller, Christine ^a,c   Jamme, Marie Françoise ^a   David, Martine ^a   Silve, Sandra ^a   Lanau, Colette ^a   Dhers, Christiane ^a   Picard, Claudine ^a   Rahier, Alain ^b   Taton, Maryse ^b   Loison, Gérard ^a   Caput, Daniel ^a   Ferrara, Pascual ^a   Lupker, Jan ^a  

^a SANOFI   (France)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c Sarofi Recherche   (France)

Author keywords

Cell line; Proliferation; Sigma receptor; SR31747A; Sterol isomerase

Indexed keywords

CHOLESTEROL; IMMUNOSUPPRESSIVE AGENT; ISOMERASE; N CYCLOHEXYL N ETHYL 3 (3 CHLORO 4 CYCLOHEXYLPHENYL) 2 PROPENYLAMINE; N CYCLOHEXYL N ETHYL 3 (3 CHLORO 4 CYCLOHEXYLPHENYL)PROPEN 2 YLAMINE; RECEPTOR SUBTYPE; SIGMA OPIATE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING SITE; CELL LINE; CHO CELL; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG RESISTANCE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

ANIMALIA;

EID: 15644367094     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1998.2560342.x     Document Type: Article

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