Molecular determinants of ERα and ERβ involved in selectivity of 16α-iodo-17β estradiol

Journal of Steroid Biochemistry and Molecular Biology

Volumn 88, Issue 1, 2004, Pages 17-26

  Bhat, Ramesh A ^a   Stauffer, Barbara ^a   Unwalla, Rayomand J ^a   Xu, Zhangbao ^a   Harris, Heather A ^a   Komm, Barry S ^a  

^a PFIZER INC   (United States)

Author keywords

16 Iodo 17 estradiol; ER ; ER ; Estradiol; Estrogen receptors; Molecular modeling

Indexed keywords

16ALPHA IODO 17BETA ESTRADIOL; ESTRADIOL DERIVATIVE; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; MUTANT PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CHIMERA; CONTROLLED STUDY; HEPATOMA CELL; HUMAN; HUMAN CELL; LIGAND BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RECEPTOR BINDING; STEROID BINDING; TRANSACTIVATION; X RAY ANALYSIS;

AMINO ACID SEQUENCE; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; COMPUTATIONAL BIOLOGY; CONSERVED SEQUENCE; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; HUMANS; LIGANDS; LIVER NEOPLASMS; LUCIFERASES; MODELS, MOLECULAR; MODELS, THEORETICAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ESTROGEN; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TRANS-ACTIVATION (GENETICS);

EID: 1542329067     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2003.10.009     Document Type: Article

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