Morphine tolerance in male and female rats

Pharmacology Biochemistry and Behavior

Volumn 77, Issue 3, 2004, Pages 517-523

  Holtman Jr , Joseph R ^a   Sloan, Jewell W ^a   Wala, Elzbieta P ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Analgesia; Locomotion; Morphine tolerance; Sex differences

Indexed keywords

MORPHINE;

ANALGESIA; ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG DOSE REGIMEN; DRUG SENSITIVITY; FEMALE; LOCOMOTION; MALE; MORPHINE TOLERANCE; MOTOR ACTIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEX DIFFERENCE; TAIL FLICK TEST;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; FEMALE; MALE; MORPHINE; MOTOR ACTIVITY; PAIN MEASUREMENT; RATS; RATS, SPRAGUE-DAWLEY; SEX CHARACTERISTICS;

EID: 1542270289     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2003.12.020     Document Type: Article

References (37)

1. Barrett A.C., Cook C.D., Terner J.M., Craft R.M., Picker M.J. Importance of sex and relative efficacy at the mu opioid receptor in the development of tolerance and cross-tolerance to the antinociceptive effects of opioids. Psychopharmacology. 158:2001;154-164.
2. Bartok R.E., Craft R.M. Sex differences in opioid antinociception. J. Pharmacol. Exp. Ther. 282:1997;769-778.
3. Berglund L.A., Simpkins J.W. Alterations in brain opiate receptor mechanisms on proestrus afternoon. Neuroendocrinology. 48:1988;394-400.
4. Boyer J.S., Morgan M.M., Craft R.M. Microinjection of morphine into rostral ventromedial medulla produces greater antinociception in male compared to female rats. Brain Res. 796:1998;315-318.
5. Cicero T.H., Nock B., Meyer E.R. Gender-related differences in the antinociceptive properties of morphine. J. Pharmacol. Exp. Ther. 279:1996;767-773.
6. Cicero T.J., Ennis T., Ogden J., Meyer E.R. Gender differences in the reinforcing properties of morphine. Pharmacol. Biochem. Behav. 65:1999;91-96.
7. Cicero T.J., Nock B., Meyer E.R. Gender-linked differences in the expression of physical dependence in the rat. Pharmacol. Biochem. Behav. 72:2002;691-697.
8. Cicero T.J., Nock B., O'Connor L., Meyer E.R. Role of steroids in sex differences in morphine-induced analgesia: activational and organizational effects. J. Pharmacol. Exp. Ther. 300:2002;695-701.
9. Cicero T.J., Aylward S.C., Meyer E.R. Gender differences in the intravenous self-administration of mu opiate agonists. Pharmacol. Biochem. Behav. 74:2003;541-549.
10. Craft R.M. Sex differences in drug- and non-drug-induced analgesia. Life Sci. 72:2003;2675-2688.
11. Craft R.M. Sex differences in opioid analgesia: 'from mouse to man'. Clin. J. Pain. 19:2003;175-186.
12. Craft R.M., Kalivas P.W., Stratmann J.A. Sex differences in discriminative stimulus effects of morphine in the rat. Behav. Pharmacol. 7:1996;764-778.
13. Craft R.M., Heideman L.M., Bartok R.E. Effect of gonadectomy on discriminative stimulus effects of morphine in female versus male rats. Drug Alcohol Depend. 53:1999;95-109.
14. Craft R.M., Stratmann J.A., Bartok R.E., Walpole T.I., King S.J. Sex differences in development of morphine tolerance and dependence in the rat. Psychopharmacology. 143:1999;1-7.
15. Fillingim R.B., Ness T.J. Sex-related hormonal influences on pain and analgesic responses. Neurosci. Biobehav. Rev. 24:2000;485-501.
16. Holtman J.R. Jr., Wala E.P., Jing X., Sloan J.W. Receptor-related sex differences in the hyperalgesic effects of mu (μ), kappa (κ), and mixed-action (μ/κ, κ/μ) opioid analgesics in rats. Soc. Neurosci. Abstr. 28(1):2002;654.9.
17. Holtman J.R. Jr., Jing X., Wala E.P. Sex-related differences in the enhancement of morphine antinociception by NMDA receptor antagonists in rats. Pharmacol. Biochem. Behav. 76:2003;285-293.
18. Holtman J.R. Jr., Sloan J.W., Jing X., Wala E.P. Modification of morphine analgesia and tolerance by flumazenil in male and female rats. Eur. J. Pharmacol. 470:2003;149-156.
19. Kasson B., George R. Endocrine influences on the actions of morphine: IV. Effects of sex and strain. Life Sci. 34:1984;1627-1634.
20. Kepler K.L., Kest B., Kiefel J.M., Cooper M.L., Bodnar R.J. Roles of gender, gonadectomy and estrous phase in the analgesic effects of intracerebroventricular morphine in rats. Pharmacol. Biochem. Behav. 34:1989;119-127.
21. Kest B., Palmese C., Hopkins E. A comparison of morphine analgesic tolerance in male and female mice. Brain Res. 879:2000;17-22.
22. Kest B., Sarton E., Dahan A. Gender differences in opioid-mediated analgesia. Anesthesiology. 93:2000;539-547.
23. Kest B., Palmese C.A., Hopkins E., Adler M., Juni A. Assessment of acute and chronic morphine dependence in male and female mice. Pharmacol. Biochem. Behav. 70:2001;149-156.
24. Krzanowska E.K., Bodnar R.J. Morphine antinociception elicited from the ventrolateral periaqueductal gray is sensitive to sex and gonadectomy differences in rats. Brain Res. 821:1999;224-230.
25. Mao J. NMDA and opioid receptors: their interactions in antinociception, tolerance, and neuroplasticity. Brain Res. Rev. 30:1999;289-304.
26. Martinez-Gomez M., Cruz Y., Salas M., Hudson R., Pacheco P. Assessing pain threshold in the rat: changes with estrus and time of day. Physiol. Behav. 55:1994;651-657.
27. Miaskowski C., Gear R.W., Levine J.D. Sex-related differences in analgesic responses. Fillingim R.B. Progress in pain research and management. Sex, gender, and pain. vol. 17:2000;209-230 IASP Press, Seattle, WA.
28. Mogil J.S., Chesler E.J., Wilson S.G., Juraska J.M., Sternberg W.F. Sex differences in thermal nociception and morphine antinociception in rodents depend on genotype. Neurosci. Biobehav. Rev. 24:2000;375-389.
29. Nock B., Cicero T.J., Wich M. Chronic exposure to morphine decreases physiologically active corticosterone in both male and female rats but by different mechanism. J. Pharmacol. Exp. Ther. 286:1998;875-882.
30. Powell K.R., Holtzman S.G. Parametric evaluation of the development of sensitization to the effect of morphine on locomotor activity. Drug Alcohol Depend. 62:2001;83-90.
31. Price D.D., Mayer D.J., Mao J., Caruso F.S. NMDA-receptor antagonists and opioid receptor interactions as related to analgesia and tolerance. J. Pain Symptom. Manage. 19(Suppl. 1):2000;7-11.
32. South S.M., Wright A.W.E., Lau M., Mather L.E., Smith M.T. Sex-related differences in antinociception and tolerance development following chronic intravenous infusion of morphine in the rat: modulatory role of testosterone via morphine clearance. J. Pharmacol. Exp. Ther. 297:2001;446-457.
33. Stoffel E.C., Ulibarri C.M., Craft R.M. Gonadal steroid hormone modulation of nociception, morphine antinociception and reproductive indicates in male and female rats. Pain. 103:2003;285-302.
34. Tallarida R.J., Murray R.B. Manual of pharmacological calculations with computer programs. 1987;26-31 Springer-Verlag, New York.
35. Vanderah T.W., Ossipov M.H., Lai J., Malan T.P. Jr., Porreca F. Mechanisms of opioid-induced pain and antinociceptive tolerance: descending facilitation and spinal dynorphin. Pain. 92:2001;5-9.
36. Wala E.P., Sloan J.W., Jing X., Holtman J.R. Jr. The effect of diazepam dependence and withdrawal on morphine-induced antinociception and changes in locomotion in male and female rats. Pharmacol. Biochem. Behav. 69:2001;475-484.
37. Wala E.P., Jing X., Sloan J.W., Holtman J.R. Jr. Sex differences in the hyperalgesic and analgesic properties of chronically administered morphine. Soc. Neurosci. Abstr. 28(1):2002;654.12.