The role of B7 molecules in the cell contact-mediated suppression of T cell mitogenesis by immunosuppressive macrophages induced with mycobacterial infection

Clinical and Experimental Immunology

Volumn 135, Issue 3, 2004, Pages 373-379

  Shimizu, T ^a   Sano, C ^a   Tomioka, H ^a  

^a SHIMANE UNIVERSITY   (Japan)

Author keywords

B7 1 molecules; Cell contact; Mycobacterium intracellulare; Suppressor macrophage; T cell mitogenesis

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 1 [N,O BIS(5 ISOQUINOLINESULFONYL) N METHYLTYROSYL] 4 PHENYLPIPERAZINE; 3 (2 HYDROXYETHYL) 1 (3 TRIFLUOROMETHYLPHENYL)QUINAZOLINE 2,4 DIONE; ADENOSINE TRIPHOSPHATE; B7 ANTIGEN; CONCANAMYCIN A; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; HERBIMYCIN A; IMMUNOLOGIC AGENT; INTERCELLULAR ADHESION MOLECULE 1; MONOCLONAL ANTIBODY; PROTEIN KINASE (CALCIUM,CALMODULIN) II; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; PURINE P2 RECEPTOR; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ANIMAL MODEL; ANTIGEN RECOGNITION; ARTICLE; BACTERIAL INFECTION; CELL CONTACT; CELL INTERACTION; CONTROLLED STUDY; DRUG EFFECT; IMMUNE DEFICIENCY; MACROPHAGE FUNCTION; MALE; MITOGENESIS; MOUSE; MYCOBACTERIUM INTRACELLULARE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUPPRESSOR CELL; T LYMPHOCYTE; TARGET CELL; UPREGULATION;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD80; ANTIGENS, DIFFERENTIATION; BLOTTING, WESTERN; CELL COMMUNICATION; CELLS, CULTURED; CONCANAVALIN A; IMMUNE TOLERANCE; LYMPHOCYTE ACTIVATION; MACROPHAGE ACTIVATION; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; MYCOBACTERIUM AVIUM-INTRACELLULARE INFECTION; T-LYMPHOCYTES;

EID: 1542269613     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2004.02403.x     Document Type: Article

References (23)

1. Hart CA, Beeching NJ, Duerden BI. Tuberculosis into the next centry. J Med Microbiol 1996; 44:1-34.
2. Falkinham JO. Epidemiology of infection by nontuberculous mycobacteria. Clin Microbiol Rev 1996; 9:177-215.
3. Ellner JJ. Suppressor adherent cells in human tuberculosis. J Immunol 1978; 121:2573-9.
4. 2 and reversal by injection of indomethacin, muramyl dipeptide, and interferon-γ. J Immunol 1986; 136:1820-7.
5. Turcotte R, Lemieux S. Mechanisms of action of Mycobacterium bovis BCG-induced suppressor cells in mitogen induced blastogenesis. Infect Immun 1982; 36:263-70.
6. Edwards D, Kirkpatrik CH. The immunology of mycobacterial diseases. Am Rev Respir Dis 1986; 134:1062-71.
7. VanHeyningen TK, Collin HL, Russell DG. IL-6 produced by macrophages infected with Mycobacterium species suppresses T cell responses. J Immunol 1997; 158:330-7.
8. Tomioka H, Saito H, Yamada Y. Characteristics of immunosuppressive macrophages induced in spleen cells by Mycobacterium avium complex infections in mice. J General Microbiol 1990; 136:965-74.
9. Tomioka H, Saito H. Characterization of immunosuppressive functions of murine peritoneal macrophages induced with various agents. J Leukoc Biol 1992; 51:24-31.
10. Tomioka H, Sato K, Maw WW et al. The role of tumor necrosis factor, interferon-γ, transforming growth factor-β, and nitric oxide in the expression of immunosuppressive functions of macrophages induced by Mycobacterium avium complex infection. J Leukoc Biol 1995; 58:704-12.
11. Tomioka H, Kishimoto T, Maw WW. Phospholipids and reactive nitrogen intermediates collaborate in expression of the T cell mitogenesis inhibitory activity of immunosuppressive macrophages induced in mycobacterial infection. Clin Exp Immunol 1996; 103:219-25.
12. Maw WW, Shimizu T, Sato K et al. Further study on the roles of the effector molecules on immunosuppressive macrophages induced by mycobacterial infection in expression of their suppressor function against mitogen-stimulated T cell proliferation. Clin Exp Immunol 1997; 108:26-33.
13. Ogasawara K, Tomioka H, Shimizu T et al. Profiles of cell-to-cell interaction of Mycobacterium intracellulare-induced immunosuppressive macrophages with target T cells in terms of suppressor signal transmission. Clin Exp Immunol 2002; 129:272-80.
14. Freeman GJ, Gray GS, Gimmi CD et al. Structure, expression, and T cell costimulatory activity of the murine homologue of the human B lymphocyte activation antigen B7. J Exp Med 1991; 174:625-31.
15. Chen C, Faherty DA, Gault A et al. Monoclonal antibody 2D10 recognizes a novel T cell costimulatory molecule on activated murine B lymphocytes. J Immunol 1994; 152:2105-14.
16. Inobe M, Linsley PS, Ledbetter JA et al. Identification of an alternatively spliced form of the murine homologue of B7. Biochem Biophys Res Commun 1994; 200:443-9.
17. Walunas TL, Lenschow DJ, Bakker CY et al. CTLA-4 can function as a negative regulator of T cell activation. Immunity 1994; 1:405-13.
18. Tivol EA, Boyd SD, McKeon S et al. CTLA4 Ig prevents lymphoproliferation and fatal multiorgan tissue destruction in CTLA-4-deficient mice. J Immunol 1997; 158:5091-4.
19. Lammas DA, Stober C, Harvey CJ et al. ATP-induced killing of mycobacteria by human macrophages is mediated by purinergic P2Z (P2X7) receptors. Immunity 1997; 7:433-44.
20. Humphreys BD, Dubyak GR. Induction of the P2Z/P2X7 nucleotide receptor and associated phospholipase D activity by lipopolyshaccharide and IFN-γ in the human THP-1 monocytic cell line. J Immunol 1996; 157:5627-37.
21. el-Moatassim C, Dubyak GR. A novel pathway for the activation of phospholipase D by P2Z purinergic receptors in BAC1.2F5 macrophages. J Biol Chem 1992; 267:23664-73.
22. Exton JH. Phospholipase D. enzymology, mechanisms of regulation, and function. Physiol Rev 1997; 77:303-20.
23. Kusner DJ, Adams J. ATP-induced killing of virulent Mycobacterium tuberculosis within human macrophages requires phospholipase D. J Immunol 2000; 164:379-88.