Non-pharmacologic approaches to graft-versus-host prevention

Blood Reviews

Volumn 19, Issue 4, 2005, Pages 203-211

  Wanko, Sam O ^a   Chao, Nelson J ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Graft versus host disease; Graft versus leukemia effect; Non pharmacologic prevention; T cell depletion

Indexed keywords

4,5 DIBROMORHODAMINE 123; ALEMTUZUMAB; CD34 ANTIGEN; CD4 ANTIGEN; CD40 LIGAND; CD5 ANTIGEN; CD6 ANTIGEN; CD69 ANTIGEN; CD8 ANTIGEN; COMPLEMENT; CYTOKINE; FAS ANTIGEN; GANCICLOVIR; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 2 RECEPTOR ALPHA; LECTIN; LIPOSOME; MEMBRANE ANTIGEN; METHOTREXATE; MONOCLONAL ANTIBODY; PADGEM PROTEIN; RHODAMINE 123; RICIN; T LYMPHOCYTE ANTIBODY; T LYMPHOCYTE RECEPTOR; TETRAMER; THYMIDINE KINASE; UNCLASSIFIED DRUG;

ADOPTIVE IMMUNOTHERAPY; ALLOGENIC BONE MARROW TRANSPLANTATION; ALLOIMMUNITY; ALLOTRANSPLANTATION; ANTIGEN EXPRESSION; CANCER RELAPSE; CANCER SURVIVAL; CELL SELECTION; CENTRIFUGATION; CHRONIC MYELOID LEUKEMIA; CLINICAL TRIAL; CYTOKINE RELEASE; CYTOTOXIC T LYMPHOCYTE; DEPLETION; DRUG TOXICITY; EPSTEIN BARR VIRUS; ERYTHROCYTE; GENE INSERTION; GRAFT FAILURE; GRAFT VERSUS HOST REACTION; HELPER CELL; HEMATOLOGIC MALIGNANCY; HERPES SIMPLEX VIRUS; HLA MATCHING; HUMAN; IMMUNOMAGNETIC SEPARATION; IMMUNOREGULATION; IMMUNOSUPPRESSIVE TREATMENT; INTERMETHOD COMPARISON; LEUKEMIA; LYMPHOMA; MEDICAL RESEARCH; MORBIDITY; MORTALITY; NATURAL KILLER CELL; NONHUMAN; PATIENT CARE; PHOTODYNAMICS; PRIORITY JOURNAL; PROPHYLAXIS; RABBIT; RECIPIENT; REVIEW; ROSETTE FORMING CELL; SOYBEAN; SUICIDE GENE; SUICIDE GENE THERAPY; T CELL DEPLETION; T LYMPHOCYTE SUBPOPULATION; TH2 CELL; TREATMENT OUTCOME;

EID: 15244362273     PISSN: 0268960X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.blre.2004.11.001     Document Type: Article

References (49)

1. D.L. Porter, and J.H. Antin The graft-versus-leukemia effects of allogeneic cell therapy Annu Rev Med 50 1999 369
2. A.J. Barrett, and V. malkovska Graft-versus-leukemia: understanding and using the allo-immune response to treat haematological malignancies Br J Haematol 93 1996 754 761
3. R. Storb, and E.D. Thomas Allogeneic bone marrow transplantation Immunol Rev 71 1983 77
4. E.D. Thomas Bone marrow transplantation for malignant diseases J Clin Oncol 1 9 1983 517
5. G.B. Vogelsang Chronic graft versus host disease Br J Haematol 125 2004 435 454
6. J. Ferrara Bone marrow transplantation: the genetic and cellular basis of resistance to engraftment and acute graft-versus-host disease Surv Immunol Res 4 4 1985 253 263
7. Ka. Dicke The selective elimination of immunological competent cells from bone marrow and lymphatic cell mixtures; mouse spleen cell fractionation on a discontinous albumin gradient Transplantation 6 1968 562 570
8. M. Wiesneth T-cell depletion versus methotrexate as GvHD-prophylaxis in allogeneic bone marrow transplantation for leukaemia Eur J Haematol 41 3 1988 243 249
9. R.T. Mitsuyasu Treatment of donor bone marrow with monoclonal anti-T-cell antibody and complement for the prevention of graft-versus-host disease. A prospective, randomized, double-blind trial Ann Intern Med 105 1 1986 20 26
10. R.E. Champlin T-cell depletion of bone marrow transplants for leukemia from donors other than HLA-identical siblings: advantage of T-cell antibodies with narrow specificities Blood 95 12 2000 3996 4003
11. F. Baron, and Y. Beguin Preemptive cellular immunotherapy after T-cell-depleted allogeneic hematopoietic stem cell transplantation Biol Blood Marrow Transplant 8 2002 351 359
12. V.T. Ho, and R.J. Soiffer The history and future of T-cell depletion as graft-versus-host disease prophylaxis for allogeneic hematopoietic stem cell transplantation Blood 98 12 2001 3192 3204
13. W.R. Drobyski Evolving strategies to address adverse transplant outcomes associated with T cell depletion J Hematother Stem Cell Res 9 2000 327 337
14. M. Korbling Allogeneic blood stem cell transplantation: peripheralization and yield of donor-derived primitive hematopoietic progenitors of engraftment and graft-versus-host disease Blood 86 1995 2842 2848
15. A.R. Datta Distinct T cell populations distinguish chronic myeloid leukaemia cells from lymphocytes in the same individual: a model for separating GVHD from GVL reactions Bone Marrow Transplant 14 4 1994 517 524
16. M.M. Horowitz Graft-versus-leukemia after bone marrow transplantation Blood 75 3 1990 555 562
17. B.J. Chen Prevention of graft-versus-host disease while preserving graft-versus-leukemia effect after selective depletion of host-reactive T cells by photodynamic cell purging process Blood 99 9 2002 3083 3088
18. T.F. Goggins, and N. Chao Depletion of reactive T cells by photodynamic cell purging and prevention of graft versus host disease Leuk Lymphoma 44 11 2003 1871 1879
19. M.B.C. Koh Selective removal of alloreactive cells from haemotopoietic stem cells graft: graft engineering for GVHD prophylaxis Bone Marrow Transplantat 23 1999 1071 1079
20. S. Maury Division rate and phenotypic differences discriminate alloreactive and non-alloreactive T cells transferred in lethally irradiated mice Blood 98 10 2001 3156 3158
21. B. Fehse Depletion of alloreactive donor T-cells using immunomagnetic cell selection Bone Marrow Transplant 25 Suppl 2 2000 S39 S42
22. M. Cavazzana-Calvo T-cell-depleted HLA non-identical bone marrow transplantation in the child: prevention of graft-versus-host reaction by administration of donor T lymphocytes alloreactive against the recipient J Soc Biol 195 1 2001 65 68
23. I. André-Schmutz Donor T lymphocyte infusion following ex vivo depletion of donor anti-host reactivity by a specific anti-interleukin-2 receptor P55 chain immunotoxin Transplant Proc 34 7 2002 2927 2928
24. K. Yamashita Severe chronic graft-versus-host disease is characterized by a preponderance of CD4(+) effector memory cells relative to central memory cells Blood 103 10 2004 3986 3988
25. B.E. Anderson Memory CD4+ T cells do not induce graft-versus-host disease J Clin Invest 112 1 2003 101 108
26. B.J. Chen Transfer of allogeneic CD62L- memory T cells without graft-versus-host disease Blood 103 4 2004 1534 1541
27. A.E. Foster Human CD62L- memory T cells are less responsive to alloantigen stimulation than CD62L+ naive T cells: potential for adoptive immunotherapy Blood July 1 2004 [abstract]
28. D.H. Fowler, and R.E. Gress Th2 and Tc2 cells in the regulation of GVHD, GVL, and graft rejection: considerations for the allogeneic transplantation therapy of leukemia and lymphoma Leuk Lymphoma 38 3-4 2000 221 234
29. D.C. Halverson In vitro generation of allospecific human CD8+ T cells of Tc1 and Tc2 phenotype Blood 90 5 1997 2089 2096
30. P. Tiberghien Ganciclovir treatment of herpes simplex thymidine kinase-transduced primary T lymphocytes: an approach for specific in vivo donor T-cell depletion after bone marrow transplantation Blood 84 1994 1333 1341
31. M.P. Rettig Transduction and selection of human T cells with novel CD34/thymidine kinase chimeric suicide genes for the treatment of graft-versus-host disease Mol Ther 8 1 2003 29 41
32. D.C. Thomis A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease Blood 97 5 2001 1249 1257
33. C. Bonini HSV Tk gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia Science 276 1997 1719 1724
34. M.I. Garin Molecular mechanism for ganciclovir resistance in human T lymphocytes transduced with retroviral vectors carrying the herpes simplex virus thymidine kinase gene Blood 97 1 2001 122 129
35. S. Skaguchi Immunologic self tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases J Immunol 155 1995 1151 1164
36. E. Suri-Payer CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells J Immunol 160 1998 1212 1218
37. M. Edinger CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation Nat Med 9 9 2003 1144 1150
38. P. Hoffmann, J. Ermann, and M. Edinger Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation J Exp Med 196 2002 389
39. A. Trenado Ex vivo selection of recipient-type alloantigen-specific CD4+CD25+ immunoregulatory T cells for the control of graft-versus-host disease after allogeneic hematopoietic stem-cell transplantation Transplantation 77 1 2004 S32 S34
40. J.L. Cohen CD4(+)CD25(+) immunoregulatory T cells: new therapeutics for graft-versus-host disease J Exp Med 196 2002 401
41. B.E. Anderson Recipient CD4+ T cells that survive irradiation regulate chronic graft-vs.-host disease Blood May 18 2004 [abstract]
42. D. Dieckmann Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood J Exp Med 193 2001 1303
43. H. Jonuleit Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood J Exp Med 193 2001 1285
44. M. Stanzani CD25 expression on donor CD4+ or CD8+ T cells is associated with an increased risk for graft-versus-host disease after HLA-identical stem cell transplantation in humans Blood 103 3 2004 1140 1146
45. N.M. Valante Functionally and structurally distinct NK-cell receptor repertoires in the peripheral blood of two human donors Immunity 7 1997 739 751
46. L. Ruggeri Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants Science 295 2002 2097 2100
47. M. Colonaa Generation of allospecific natural killer cells by stimulation across polymorphism of HLA-C Science 260 1993 1121 1124
48. A. Bishara The beneficial role of inhibitory KIR genes of HLA class I NK epitopes in haploidentically mismatched stem cell allografts may be masked by residual donor-alloreactive T cells causing GVHD Tissue Antigens 63 3 2004 204 211
49. C.A. Ellison Depletion of natural killer cells from the graft reduces interferon-gamma levels and lipopolysaccharide-induced tumor necrosis factor-alpha release in F1 hybrid mice with acute graft-versus-host disease Transplantation 66 3 1998 284 294