-
1
-
-
0026637845
-
Novel mechanism(s) of resistance to 5-fluorouracil in human colon cancer (Hct-8) sublines following exposure to 2 different clinically relevant dose schedules
-
Aschele C, Sobrero A, Faderan MA, Bertino JR (1992) Novel mechanism(s) of resistance to 5-fluorouracil in human colon cancer (Hct-8) sublines following exposure to 2 different clinically relevant dose schedules. Cancer Res 52: 1855-1864
-
(1992)
Cancer Res
, vol.52
, pp. 1855-1864
-
-
Aschele, C.1
Sobrero, A.2
Faderan, M.A.3
Bertino, J.R.4
-
2
-
-
0036682041
-
Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma: Eastern Cooperative Oncology Group Trial E2297
-
Berlin JD, Catalano P, Thomas JP, Kugler JW, Haller DG, Benson AB (2002) Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma: Eastern Cooperative Oncology Group Trial E2297. J Clin Oncol 20: 3270-3275
-
(2002)
J Clin Oncol
, vol.20
, pp. 3270-3275
-
-
Berlin, J.D.1
Catalano, P.2
Thomas, J.P.3
Kugler, J.W.4
Haller, D.G.5
Benson, A.B.6
-
3
-
-
8244254377
-
Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial
-
Burris HA, Moore MJ, Andersen J, Green MR, Rothenberg ML, Madiano MR, Cripps MC, Portenoy RK, Storniolo AM, Tarassoff P, Nelson R, Dorr FA, Stephens CD, VanHoff DD (1997) Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol 15: 2403-2413
-
(1997)
J Clin Oncol
, vol.15
, pp. 2403-2413
-
-
Burris, H.A.1
Moore, M.J.2
Andersen, J.3
Green, M.R.4
Rothenberg, M.L.5
Madiano, M.R.6
Cripps, M.C.7
Portenoy, R.K.8
Storniolo, A.M.9
Tarassoff, P.10
Nelson, R.11
Dorr, F.A.12
Stephens, C.D.13
Vanhoff, D.D.14
-
4
-
-
0016916438
-
Prediction of creatinine clearance from serum creatinine
-
Cockcroft DW, Gault MH (1976) Prediction of creatinine clearance from serum creatinine. Nephron 16: 31-41
-
(1976)
Nephron
, vol.16
, pp. 31-41
-
-
Cockcroft, D.W.1
Gault, M.H.2
-
5
-
-
0029991497
-
Long-term survival after curative resection for pancreatic ductal adenocarcinoma - Clinicopathologic analysis of 5-year survivors
-
Conlon KC, Klimstra DS, Brennan MF (1996) Long-term survival after curative resection for pancreatic ductal adenocarcinoma - clinicopathologic analysis of 5-year survivors. Ann Surg 223: 273-279
-
(1996)
Ann Surg
, vol.223
, pp. 273-279
-
-
Conlon, K.C.1
Klimstra, D.S.2
Brennan, M.F.3
-
6
-
-
0037816604
-
Gemcitabine increases systemic 5-fluorouracil exposure in advanced cancer patients
-
Correale P, Cerretani D, Marsili S, Pozzessere D, Petrioli R, Messinese S, Sabatino M, Roviello F, Pinto E, Francini G, Giorgi G (2003a) Gemcitabine increases systemic 5-fluorouracil exposure in advanced cancer patients. Eur J Cancer 39: 1547-1551
-
(2003)
Eur J Cancer
, vol.39
, pp. 1547-1551
-
-
Correale, P.1
Cerretani, D.2
Marsili, S.3
Pozzessere, D.4
Petrioli, R.5
Messinese, S.6
Sabatino, M.7
Roviello, F.8
Pinto, E.9
Francini, G.10
Giorgi, G.11
-
7
-
-
2642527436
-
Gemcitabine and 5 fluorouracil in the treatment of patients with pancreas and colo-rectal carcinoma: A clinical and pharmacological study
-
January 31-February 3 2000, Paris, France, abs. no. 1-293
-
Correale P, Cerretani D, Petrioli R, Marsili S, Giorgi G, Francini G (2000) Gemcitabine and 5 fluorouracil in the treatment of patients with pancreas and colo-rectal carcinoma: a clinical and pharmacological study. ICACT 10th International Congress on Anti-Cancer Treatment January 31-February 3 2000, Paris, France, abs. no. 1-293
-
(2000)
ICACT 10th International Congress on Anti-Cancer Treatment
-
-
Correale, P.1
Cerretani, D.2
Petrioli, R.3
Marsili, S.4
Giorgi, G.5
Francini, G.6
-
8
-
-
0042622326
-
A novel biweekly pancreatic cancer treatment schedule with gemcitabine, 5-fluorouracil and folinic acid
-
Correale P, Messinese S, Marsili S, Ceciarini F, Pozzessere D, Petrioli R, Sabatino M, Cerretani D, Pellegrini M, Di Palma T, Neri A, Calvanese A, Pinto E, Giorgi G, Francini G (2003b) A novel biweekly pancreatic cancer treatment schedule with gemcitabine, 5-fluorouracil and folinic acid. Br J Cancer 89: 239-242
-
(2003)
Br J Cancer
, vol.89
, pp. 239-242
-
-
Correale, P.1
Messinese, S.2
Marsili, S.3
Ceciarini, F.4
Pozzessere, D.5
Petrioli, R.6
Sabatino, M.7
Cerretani, D.8
Pellegrini, M.9
Di Palma, T.10
Neri, A.11
Calvanese, A.12
Pinto, E.13
Giorgi, G.14
Francini, G.15
-
9
-
-
0033135803
-
Prognostic factors in nonresectable pancreatic adenocarcinoma: A rationale to design therapeutic trials
-
Cubiella J, Castells A, Fondevila C, Sans M, Sabater L, Navarro S, Fernandez-Cruz L (1999) Prognostic factors in nonresectable pancreatic adenocarcinoma: a rationale to design therapeutic trials. Am J Gastroenterol 94: 1271-1278
-
(1999)
Am J Gastroenterol
, vol.94
, pp. 1271-1278
-
-
Cubiella, J.1
Castells, A.2
Fondevila, C.3
Sans, M.4
Sabater, L.5
Navarro, S.6
Fernandez-Cruz, L.7
-
10
-
-
0031888857
-
Mature results from three large controlled studies with raltitrexed ('Tomudex')
-
Cunningham D (1998) Mature results from three large controlled studies with raltitrexed ('Tomudex'). Br J Cancer 77: 15-21
-
(1998)
Br J Cancer
, vol.77
, pp. 15-21
-
-
Cunningham, D.1
-
11
-
-
0036860329
-
Phase II study of a fixed dose-rate infusion of gemcitabine associated with uracil/tegafur in advanced carcinoma of the pancreas
-
Feliu J, Mel R, Borrega P, Gomez LL, Escudero P, Dorta J, Castro J, Vazquez-Estevez SE, Bolanos M, Espinosa E, Baron MG (2002) Phase II study of a fixed dose-rate infusion of gemcitabine associated with uracil/tegafur in advanced carcinoma of the pancreas. Ann Oncol 13: 1756-1762
-
(2002)
Ann Oncol
, vol.13
, pp. 1756-1762
-
-
Feliu, J.1
Mel, R.2
Borrega, P.3
Gomez, L.L.4
Escudero, P.5
Dorta, J.6
Castro, J.7
Vazquez-Estevez, S.E.8
Bolanos, M.9
Espinosa, E.10
Baron, M.G.11
-
12
-
-
0036155276
-
Patterns of elevation of plasma 2′-deoxyuridine, a surrogate marker of thymidylate synthase (TS) inhibition, after administration of two different schedules of 5-fluorouracil and the specific TS inhibitors raltitrexed (Tomudex) and ZD9331
-
Ford HER, Mitchell F, Cunningham D, Farrugia DC, Hill ME, Rees C, Calvert AH, Judson IR, Jackman AL (2002) Patterns of elevation of plasma 2′-deoxyuridine, a surrogate marker of thymidylate synthase (TS) inhibition, after administration of two different schedules of 5-fluorouracil and the specific TS inhibitors raltitrexed (Tomudex) and ZD9331. Clin Cancer Res 8: 103-109
-
(2002)
Clin Cancer Res
, vol.8
, pp. 103-109
-
-
Ford, H.E.R.1
Mitchell, F.2
Cunningham, D.3
Farrugia, D.C.4
Hill, M.E.5
Rees, C.6
Calvert, A.H.7
Judson, I.R.8
Jackman, A.L.9
-
13
-
-
0029816590
-
Chemotherapy improves survival and quality of life in advanced pancreatic and biliary cancer
-
Glimelius B, Hoffman K, Sjoden PO, Jacobsson G, Sellstrom H, Enander LK, Linne T, Svensson C (1996) Chemotherapy improves survival and quality of life in advanced pancreatic and biliary cancer. Ann Oncol 7: 593-600
-
(1996)
Ann Oncol
, vol.7
, pp. 593-600
-
-
Glimelius, B.1
Hoffman, K.2
Sjoden, P.O.3
Jacobsson, G.4
Sellstrom, H.5
Enander, L.K.6
Linne, T.7
Svensson, C.8
-
14
-
-
0038121455
-
Chemotherapy for advanced pancreatic cancer
-
Haller DG (2003) Chemotherapy for advanced pancreatic cancer. Int J Radiat Oncol Biol Phys 56: 16-23
-
(2003)
Int J Radiat Oncol Biol Phys
, vol.56
, pp. 16-23
-
-
Haller, D.G.1
-
15
-
-
0023880296
-
Continuous 5-fluorouracil (5Fu) infusion in carcinoma of the pancreas - A Phase-II Study
-
Hansen R, Quebbeman E, Ritch P, Chitambar C, Anderson T (1988) Continuous 5-fluorouracil (5Fu) infusion in carcinoma of the pancreas - a Phase-II Study. Am J Med Sci 295: 91-93
-
(1988)
Am J Med Sci
, vol.295
, pp. 91-93
-
-
Hansen, R.1
Quebbeman, E.2
Ritch, P.3
Chitambar, C.4
Anderson, T.5
-
16
-
-
0031708742
-
Review article: Current treatment and optimal patient management in pancreatic cancer
-
Haycox A, Lombard M, Neoptolemos J, Walley T (1998) Review article: current treatment and optimal patient management in pancreatic cancer. Aliment Pharmacol Therap 12: 949-964
-
(1998)
Aliment Pharmacol Therap
, vol.12
, pp. 949-964
-
-
Haycox, A.1
Lombard, M.2
Neoptolemos, J.3
Walley, T.4
-
17
-
-
0033012340
-
Phase I-II study of gemcitabine and fluorouracil as a continuous infusion in patients with pancreatic cancer
-
Hidalgo M, Castellano D, Paz-Ares L, Gravalos C, Diaz-Puente M, Hitt R, Alonso S, Cortes-Funes H (1999) Phase I-II study of gemcitabine and fluorouracil as a continuous infusion in patients with pancreatic cancer. J Clin Oncol 17: 585-592
-
(1999)
J Clin Oncol
, vol.17
, pp. 585-592
-
-
Hidalgo, M.1
Castellano, D.2
Paz-Ares, L.3
Gravalos, C.4
Diaz-Puente, M.5
Hitt, R.6
Alonso, S.7
Cortes-Funes, H.8
-
19
-
-
15444379214
-
In vitro concentration response studies of gemcitabine as experimental base for regional chemotherapeutic studies
-
Kornmann M, Link KH, Butzer U, Blatter J, Beger HG (1999) In vitro concentration response studies of gemcitabine as experimental base for regional chemotherapeutic studies. Eur J Cancer 35: S294
-
(1999)
Eur J Cancer
, vol.35
-
-
Kornmann, M.1
Link, K.H.2
Butzer, U.3
Blatter, J.4
Beger, H.G.5
-
20
-
-
0037481752
-
Activity of raltitrexed and gemcitabine in advanced pancreatic cancer
-
Kralidis E, Aebi S, Friess H, Buchler MW, Borner MM (2003) Activity of raltitrexed and gemcitabine in advanced pancreatic cancer. Ann Oncol 14: 574-579
-
(2003)
Ann Oncol
, vol.14
, pp. 574-579
-
-
Kralidis, E.1
Aebi, S.2
Friess, H.3
Buchler, M.W.4
Borner, M.M.5
-
21
-
-
12144285613
-
Phase II study of gemcitabine combined with uracil-tegafur in metastatic pancreatic cancer
-
Lee J, Park JO, Kim WS, Lee SI, Song SY, Lim dH, Choi SH, Heo JS, Lee KT, Lee JK, Kim K, Jung CW, Im YH, Lee MH, Kang WK, Park K (2004) Phase II study of gemcitabine combined with uracil-tegafur in metastatic pancreatic cancer. Oncology 66: 32-37
-
(2004)
Oncology
, vol.66
, pp. 32-37
-
-
Lee, J.1
Park, J.O.2
Kim, W.S.3
Lee, S.I.4
Song, S.Y.5
Lim, D.H.6
Choi, S.H.7
Heo, J.S.8
Lee, K.T.9
Lee, J.K.10
Kim, K.11
Jung, C.W.12
Im, Y.H.13
Lee, M.H.14
Kang, W.K.15
Park, K.16
-
23
-
-
0028291349
-
Chemotherapy prolongs survival in inoperable pancreatic-carcinoma
-
Palmer KR, Kerr M, Knowles G, Cull A, Carter DC, Leonard RCF (1994) Chemotherapy prolongs survival in inoperable pancreatic-carcinoma. Br J Surg 81: 882-885
-
(1994)
Br J Surg
, vol.81
, pp. 882-885
-
-
Palmer, K.R.1
Kerr, M.2
Knowles, G.3
Cull, A.4
Carter, D.C.5
Leonard, R.C.F.6
-
25
-
-
0029556670
-
Phase II trial of ZD1694 (Tomudex(TM)) in patients with advanced pancreatic cancer
-
Pazdur R, Meropol NJ, Casper ES, Fuchs C, Douglass HO, Vincent M, Abbruzzese JL (1995) Phase II trial of ZD1694 (Tomudex(TM)) in patients with advanced pancreatic cancer. Invest New Drugs 13: 355-358
-
(1995)
Invest New Drugs
, vol.13
, pp. 355-358
-
-
Pazdur, R.1
Meropol, N.J.2
Casper, E.S.3
Fuchs, C.4
Douglass, H.O.5
Vincent, M.6
Abbruzzese, J.L.7
-
26
-
-
0033801694
-
Basis for effective combination cancer chemotherapy with antimetabolites
-
Peters GJ, van der Wilt CL, Van Moorsel CJ, Kroep JR, Bergman AM, Ackland SP (2000) Basis for effective combination cancer chemotherapy with antimetabolites. Pharmacol Ther 87: 227-253
-
(2000)
Pharmacol Ther
, vol.87
, pp. 227-253
-
-
Peters, G.J.1
Van Der Wilt, C.L.2
Van Moorsel, C.J.3
Kroep, J.R.4
Bergman, A.M.5
Ackland, S.P.6
-
27
-
-
0032843811
-
Estimates of the worldwide mortality from 25 cancers in 1990
-
Pisani P, Parkin DM, Bray F, Ferlay J (1999) Estimates of the worldwide mortality from 25 cancers in 1990. Int J Cancer 83: 18-29
-
(1999)
Int J Cancer
, vol.83
, pp. 18-29
-
-
Pisani, P.1
Parkin, D.M.2
Bray, F.3
Ferlay, J.4
-
28
-
-
0031756707
-
Cytotoxicity and DNA fragmentation associated with sequential gemcitabine and 5-fluoro-2′-deoxyuridine in HT-29 colon cancer cells
-
Ren Q, Kao V, Grem JL (1998) Cytotoxicity and DNA fragmentation associated with sequential gemcitabine and 5-fluoro-2′-deoxyuridine in HT-29 colon cancer cells. Clin Cancer Res 4: 2811-2818
-
(1998)
Clin Cancer Res
, vol.4
, pp. 2811-2818
-
-
Ren, Q.1
Kao, V.2
Grem, J.L.3
-
30
-
-
0142121290
-
Randomized phase II comparison of dose-intense gemcitabine: Thirty-minute infusion and fixed dose rate infusion in patients with pancreatic adenocarcinoma
-
Tempero M, Plunkett W, van Haperen VR, Hainsworth J, Hochster H, Lenzi R, Abbruzzese J (2003) Randomized phase II comparison of dose-intense gemcitabine: thirty-minute infusion and fixed dose rate infusion in patients with pancreatic adenocarcinoma. J Clin Oncol 21: 3402-3408
-
(2003)
J Clin Oncol
, vol.21
, pp. 3402-3408
-
-
Tempero, M.1
Plunkett, W.2
Van Haperen, V.R.3
Hainsworth, J.4
Hochster, H.5
Lenzi, R.6
Abbruzzese, J.7
-
31
-
-
0029805907
-
Activity of gemcitabine in a human tumor cloning assay as a basis for clinical trials with gemcitabine
-
San Antonio Drug Development Team
-
Von Hoff DD (1996) Activity of gemcitabine in a human tumor cloning assay as a basis for clinical trials with gemcitabine. San Antonio Drug Development Team. Invest New Drugs 14: 265-270
-
(1996)
Invest New Drugs
, vol.14
, pp. 265-270
-
-
Von Hoff, D.D.1
|