High hydrostatic pressure dissociates early aggregates of TTR 105-115, but not the mature amyloid fibrils

Journal of Molecular Biology

Volumn 347, Issue 5, 2005, Pages 903-909

  Dirix, Carolien ^a   Meersman, Filip ^b   MacPhee, Cait E ^c   Dobson, Christopher M ^b   Heremans, Karel ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Amyloid; Atomic force microscopy; Fourier transform infrared spectroscopy; Hydrogen bonds; Transthyretin

Indexed keywords

AMYLOID; PEPTIDE DERIVATIVE; PREALBUMIN; WATER;

ARTICLE; ATOMIC FORCE MICROSCOPY; DISSOCIATION; ELECTRICITY; HYDROGEN BOND; HYDROPHOBICITY; HYDROSTATIC PRESSURE; INFRARED SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN STABILITY; PROTEIN STRUCTURE;

EID: 15244356060     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2005.01.073     Document Type: Article

References (41)

1. C.M. Dobson Protein folding and misfolding Nature 426 2003 884 890
2. F. Chiti, P. Webster, N. Taddei, A. Clark, M. Stefani, G. Ramponi, and C. Dobson Designing conditions for in vitro formation of amyloid protofilaments and fibrils Proc. Natl Acad. Sci. USA 96 1999 3590 3594
3. M. Fändrich, and C.M. Dobson The behaviour of polyamino acids reveals an inverse side chain effect in amyloid structure formation EMBO J. 21 2002 5682 5690
4. D. Shortle The denatured state (the other half of the folding equation) and its role in protein stability FASEB J. 10 1996 27 34
5. J.L. Silva, D. Foguel, and C. Royer Pressure provides new insights into protein folding, dynamics and structure Trends Biochem. Sci. 26 2001 612 618
6. C. Balny, P. Masson, and K. Heremans High pressure effects on biological macromolecules: from structural changes to alteration of cellular processes Biochim. Biophys. Acta 1595 2002 3 10
7. A.D. Ferrão-Gonzales, S.O. Souto, J.L. Silva, and D. Foguel The preaggregated state of an amyloidogenic protein: hydrostatic pressure converts native transthyretin into the amyloidogenic state Proc. Natl Acad. Sci. USA 97 2000 6645 6650
8. D. Foguel, M.C. Suarez, A.D. Ferrão-Gonzales, T.C.R. Porto, L. Palmieri, and C.M. Einsiedler Dissociation of amyloid fibrils of alpha-synuclein and transthyretin by pressure reveals their reversible nature and the formation of water-excluded cavities Proc. Natl Acad. Sci. USA 100 2003 9831 9836
9. A. Gustavsson, U. Engström, and P. Westermark Normal transthyretin and synthetic transthyretin fragments form amyloid-like fibrils in vitro Biochem. Biophys. Res. Commun. 175 1991 1159 1164
10. M.M. Sousa, and M.J. Saraiva Neurodegeneration in familial amyloid polyneuropathy: from pathology to molecular signaling Prog. Neurobiol. 71 2003 385 400
11. A.M. Damas, and M.J. Saraiva TTR amyloidosis-structural features leading to protein aggregation and their implications on therapeutic strategies J. Struct. Biol. 130 2000 290 299
12. C.P. Jaroniec, C.E. MacPhee, N.S. Astrof, C.M. Dobson, and R.G. Griffin Molecular conformation of a peptide fragment of transthyretin in an amyloid fibril Proc. Natl Acad. Sci. USA 99 2002 16748 16753
13. C.P. Jaroniec, C.E. MacPhee, V.S. Bajaj, M.T. McMahon, C.M. Dobson, and R.G. Griffin High-resolution molecular structure of a peptide in an amyloid fibril determined by magic angle spinning NMR spectroscopy Proc. Natl Acad. Sci. USA 101 2004 711 716
14. E. Paci, J. Gspöner, X. Salvatella, and M. Vendruscolo Molecular dynamics studies of the process of amyloid aggregation of peptide fragments of transthyretin J. Mol. Biol. 340 2004 555 569
15. M. Jackson, and H.H. Mantsch The use and misuse of FTIR spectroscopy in the determination of protein structure Crit. Rev. Biochem. Mol. Biol. 30 1995 95 120
16. D.M. Byler, and H. Susi Examination of the secondary structure of proteins by deconvolved FTIR spectra Biopolymers 25 1986 469 487
17. L. Nielsen, S. Frokjaer, J.F. Carpenter, and J. Brange Studies of the structure of insulin fibrils by Fourier transform infrared (FTIR) spectroscopy and electron microscopy J. Pharm. Sci. 90 2001 29 37
18. L.A. Munishkina, C. Phelan, V.N. Uversky, and A.L. Fink Conformational behavior and aggregation of α-synuclein in organic solvents: modelling the effects of membranes Biochemistry 42 2003 2720 2730
19. J. Zurdo, J.I. Guijarro, and C.M. Dobson Preparation and characterization of purified amyloid fibrils J. Am. Chem. Soc. 123 2001 8141 8142
20. B. Seilheimer, B. Bohrmann, L. Bondolfi, F. Muller, D. Stuber, and H. Dobeli The toxicity of the Alzheimer's beta-amyloid peptide correlates with a distinct fiber morphology J. Struct. Biol. 119 1997 59 71
21. S. Xu, B. Bevis, and M.F. Arnsdorf The assembly of amyloidogenic yeast sup35 as assessed by scanning (atomic) force microscopy: an analogy to linear colloidal aggregation? Biophys. J. 81 2001 446 454
22. F.G. De Felice, M.N.N. Vieira, M.N.L. Meirelles, L.A. Morozova-Roche, C.M. Dobson, and S.T. Ferreira Formation of amyloid aggregates from human lysozyme and its disease-associated variants using hydrostatic pressure FASEB J. 18 2004 1099 1101
23. K. Heremans, K. Goossens, and L. Smeller High-pressure effects in molecular biophysics and enzymology J.L. Markley D.B. Northrop C.A. Royer Pressure-tuning Spectroscopy of Proteins: Fourier Transform Infrared Studies in the Diamond Anvil Cell 1996 Oxford University Press Oxford 44 61
24. C. Dirix, F. Meersman, L. Smeller, and K. Heremans Unfolding and fibrillogenesis of insulin: temperature, pressure and chemistry High Pressure Res. 22 2002 733 736
25. K.I. Yamaguchi, H. Katou, M. Hoshino, K. Hasegawa, H. Naiki, and Y. Goto Core and heterogeneity of beta(2)-microglobulin amyloid fibrils as revealed by H/D exchange J. Mol. Biol. 338 2004 559 571
26. U. Baxa, P.D. Ross, R.B. Wickner, and A.C. Steven The N-terminal prion domain of Ure2p converts from an unfolded to a thermally resistant conformation upon filament formation J. Mol. Biol. 339 2004 259 264
27. J. Brange, L. Andersen, E.D. Laursen, G. Meyn, and E. Rasmussen Toward understanding insulin fibrillation J. Pharm. Sci. 86 1997 517 525
28. K. Heremans, and L. Smeller Protein structure and dynamics at high pressure Biochim. Biophys. Acta 1386 1998 353 370
29. K.J. Frye, and C.A. Royer Probing the contribution of internal cavities to the volume change of protein unfolding under pressure Protein Sci. 7 1998 2217 2222
30. M. Balbirnie, R. Grothe, and D.S. Eisenberg An amyloid-forming peptide from the yeast prion Sup35 reveals a dehydrated β-sheet structure for amyloid Proc. Natl Acad. Sci. USA 98 2001 2375 2380
31. R. Diaz-Avalos, C. Long, E. Fontano, M. Balbirnie, R. Grothe, D. Eisenberg, and D.L.D. Caspar Cross-beta order and diversity in nanocrystals of an amyloid-forming peptide J. Mol. Biol. 330 2003 1165 1175
32. I. Kheterpal, S. Zhou, K.D. Cook, and R. Wetzel Beta amyloid fibrils possess a core structure highly resistant to hydrogen exchange Proc. Natl Acad. Sci. USA 97 2000 13597 13601
33. A.V. Kajava, U. Baxa, R.B. Wickner, and A.C. Steven A model for Ure2p prion filaments and other amyloids: the parallel superpleated β-structure Proc. Natl Acad. Sci. USA 101 2004 7885 7890
34. B.B. Boonyaratanakornkit, C. Beum Park, and D.S. Clark Pressure effects on intra- and intermolecular interactions within proteins Biochim. Biophys. Acta 1595 2002 235 249
35. T.N. Niraula, T. Konno, H. Li, H. Yamada, K. Akasaka, and H. Tachibana Pressure-dissociable reversible assembly of intrinsically denatured lysozyme is a precursor for amyloid fibrils Proc. Natl Acad. Sci. USA 101 2004 4089 4093
36. L. Smeller, P. Rubens, and K. Heremans Pressure effect on the temperature-induced unfolding and tendency to aggregate of myoglobin Biochemistry 38 1999 3816 3820
37. Y. Cordeiro, J. Kraineva, R. Ravindra, M.L.T.R. Lima, M.P.B. Gomes, and D. Foguel Hydration and packing effects on prion folding and beta-sheet conversion: high-pressure spectroscopy and pressure perturbation calorimetry studies J. Biol. Chem. 279 2004 32354 32359
38. J.L. Silva, and G. Weber Pressure stability of proteins Annu. Rev. Phys. Chem. 44 1993 89 113
39. A. Fernández, T.R. Sosnick, and A. Colubri Dynamics of hydrogen bond desolvation in protein folding J. Mol. Biol. 321 2002 569 675
40. M.S. Cheung, A.E. Garcia, and J.N. Onuchic Protein folding mediated by solvation: water expulsion and formation of the hydrophobic core occur after the structural collapse Proc. Natl Acad. Sci. USA 99 2002 685 690
41. F. Meersman, and K. Heremans High pressure induces the formation of aggregation-prone states of proteins under reducing conditions Biophys. Chem. 104 2003 297 304