Dissociation of amyloid fibrils of α-synuclein and transthyretin by pressure reveals their reversible nature and the formation of water-excluded cavities

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 17, 2003, Pages 9831-9836

  Foguel, Débora ^a   Suarez, Marisa C ^a   Ferrão Gonzales, Astria D ^a   Porto, Thais C R ^a   Palmieri, Leonardo ^a   Einsiedler, Carla M ^a   Andrade, Leonardo R ^a   Lashuel, Hilal A ^b   Lansbury, Peter T ^b   Kelly, Jeffery W ^c   Silva, Jerson L ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b Brigham and Women's Hospital Center for Neurologic Diseases   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; AMYLOID; CONGO RED; PREALBUMIN; THIOFLAVINE; WATER;

ALZHEIMER DISEASE; ARTICLE; BETA SHEET; CIRCULAR DICHROISM; DISSOCIATION; DISSOLUTION; DRUG SCREENING; HYDROSTATIC PRESSURE; PARKINSON DISEASE; PRESSURE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DENATURATION; PROTEIN FOLDING; TRANSMISSION ELECTRON MICROSCOPY;

EID: 0043194011     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.1734009100     Document Type: Article

References (46)

1. Sacchettini, J. C. & Kelly, J. W. (2002) Nar. Drug Discov. 4, 267-275.
2. Holden, C. (2002) Science 297, 500-502.
3. Coelho, T. (1996) Curr. Opin. Neurol. 9, 355-359.
4. Horwich, A. (2002) J. Clin. Invest. 110, 1221-1232.
5. Hammarstrom, P., Schneider, F. & Kelly, J. W. (2001) Science 28, 2459-2462.
6. Spillantini, M. G., Schmidt, M. L., Lee, V. M. Y., Trojanowski, J. Q., Jakes, R. & Goedert, M. (1997) Nature 388, 839-840.
7. Forno, L. S. (1996) J. Neuropathol. Exp. Neurol. 55, 259-272.
8. Spillantini, M. G., Crowther, R. A., Jakes, R., Hasegawa, M. & Goedert, M. (1998) Proc. Natl. Acad. Sci. USA 95, 6469-6473.
9. Polymeropoulos, M. H., Lavedan, C., Leroy, E., Ide, S. E., Dehejia, A., Dutra, A., Pike, B., Root, H., Rubenstein, J., Boyer, R., et al., (1997) Science 276, 2045-2047.
10. Benson, M. D. (1989) Trends Neurosci. 12, 88-92.
11. Gorovits, B. M. & Horowitz, P. M. (1998) Biochemistry 37, 6132-6135.
12. Foguel, D., Robinson, C. R., deSousa, P. C., Jr., Silva, J. L. & Robinson, A. S. (1999) Biotechnol. Bioeng. 63, 552-558.
13. Meersman, F., Smeller, L. & Heremans, K. (2002) Biophys. J. 82, 2635-2644.
14. Ferrão-Gonzales, A. D., Souto, S. O., Silva, J. L. & Foguel, D. (2000) Proc. Natl. Acad. Sci. USA 97, 6445-6450.
15. Silva, J. L., Foguel, D. & Royer, C. A. (2001) Trends Biochem. Sci. 26, 612-618.
16. Lai, Z., Colon, W. & Kelly, J. W. (1996) Biochemistry 35, 6470-6482.
17. Conway, K. A., Harper, J. D. & Lansbury, P. T., Jr. (1998) Nat. Med. 4, 1318-1320.
18. Glover, J. R., Kowal, A. S., Schirmen, E. C., Patino, M. M., Liu, J. & Lindquist, S. (1997) Cell 89, 811-819.
19. MacCutchen, S. L., Kelly, J. W. & Colon, W. (1993) Biochemistry 32, 12119-12127.
20. MacCutchen, S. L., Lai, Z., Miroy, G., Kelly, J. W. & Colon, W. (1995) Biochemistry 34, 13527-13536.
21. Lashuel, H. A., Lai, Z. & Kelly, J. W. (1998) Biochemistry 37, 17851-17864.
22. Quintas, A., Saraiva, M. J. & Brito, R. M. M. (1999) J. Biol. Chem. 274, 32943-32949.
23. Hammarstrom, P., Jiang, X., Hurshman, A. R., Powers, E. T. & Kelly, J. W. (2002) Proc. Natl. Acad. Sci. USA 99, 16427-16432.
24. St. John, R. J., Carpenter, J. F. & Randolph, T. W. (1999) Proc. Natl. Acad. Sci. USA 96, 13029-13033.
25. Heremans, K. & Smeller, S. (1998) Biochim. Biophys. Acta 2, 353-370.
26. Silva, J. L. & Weber, G. (1993) Annu. Rey. Phys. Chem. 44, 89-113.
27. Sousa, M. M., Cardoso, I., Fernandes, R., Guimaraes, A. & Saraiva, M. J. (2001) Am. J. Pathol. 6, 1993-2000.
28. Rosen, H. N., Moses, A. C., Murell, J., Liepnieks, J. J. & Benson, M. D. (1993) J. Clin. Endocrinol. Metab. 77, 370-374.
29. Baures, P. W., Oza, V. B., Peterson, S. A. & Kelly, J. W. (1999) Bioorg. Med. Chem. 7, 1339-1347.
30. Klabunde, T., Petrassi, H. M., Oza, V. B., Raman, P., Kelly, J. W. & Sacchettini, J. C. (2000) Nat. Struct. Biol. 4, 312-321.
31. Oza, V. B., Smith, C., Raman, P., Koepf, E. K., Lashuel, H. A., Petrassi, H. M., Chiang, K. P., Powers, E. T., Sachettinni, J. & Kelly, J. W. (2002) J. Med. Chem. 45, 321-332.
32. Ferrão-Gonzales, A. D., Palmieri, L. C., Valory, M., Silva, J. L., Lashuel, H., Kelly, J. W. & Foguel, D. (2003) J. Mol. Biol 328, 963-974.
33. Serpell, L. C., Sunde, M., Benson, M. D., Tennent, G. A., Pepys, M. B. & Fraser, P. A. (2000) J. Mol. Biol. 300, 1033-1039.
34. Wood, S. J., Wypych, J., Steavenson, S., Louis, J. C., Citron, M. & Biere, A. L. (1999) J. Biol. Chem. 274, 19509-19512.
35. Li, J., Uverski, V. N. & Fink, A. L. (2001) Biochemistry 40, 11604-11613.
36. Eriksson, A. E., Baase, W. A., Zhang, X. J., Heinz, D. W., Blaber, M., Baldwin, E. P. & Matthews, B. W. (1992) Science 255, 178-183.
37. Hummer, G., Garde, S., Garcia, A. E., Paulaitis, M. E. & Pratt, L. R. (1998) Proc. Natl. Acad. Sci. USA 95, 1552-1555.
38. Hillson, N., Onuchic, J. N. & Garcia, A. E. (1999) Proc. Natl. Acad. Sci. USA 96, 14848-14853.
39. Oliveira, A. C., Gaspar, L. P., Da Poian, A. T. & Silva, J. L. (1994) J. Mol. Biol. 240, 184-187.
40. Foguel, D. & Silva, J. L. (1994) Proc. Natl. Acad. Sci. USA 17, 8244-8247.
41. Torrent, J., Alvarez-Martinez, M. T., Heitz, F., Liautard, J. P., Balny, C. & Lange, R. (2003) Biochemistry 42, 1318-1325.
42. Brown, P., Meyer, R., Cardone, F. & Pocchiari, M. (2003) Proc. Natl. Acad. Sci. USA 100, 6093-6097.
43. Zhou, J.-M., Zhu, L., Balny, C. & Perrett, S. (2001) Biochem. Biophys. Res. Commun. 287, 147-152.
44. Goldberg, M. S. & Lansbury, P. T., Jr. (2000) Nat. Cell Biol. 7, E115-E119.
45. Bucciantini, M., Giannoni, E., Chiti, F., Baroni, F., Formigli, L., Zurdo, J., Taddei, N., Ramponi, G., Dobson, C. M. & Stefani, M. (2002) Nature 416, 507-511.
46. Lashuel, H. A., Hartley, D., Petre, B. M., Walz, T. & Lansbury, P. T., Jr. (2002) Nature 418, 291.