Recruitment and expansion of dendritic cells in vivo potentiate the immunogenicity of plasmid DNA vaccines

Journal of Clinical Investigation

Volumn 114, Issue 9, 2004, Pages 1334-1342

  Sumida, Shawn M ^a   McKay, Paul F ^b   Truitt, Diana M ^a   Kishko, Michael G ^a   Arthur, Janelle C ^a   Seaman, Michael S ^a   Jackson, Shawn S ^a   Gorgone, Darci A ^a   Lifton, Michelle A ^a   Letvin, Norman L ^a   Barouch, Dan H ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^c BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA VACCINE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; PLASMID DNA; PROTEIN TYROSINE KINASE; CANCER VACCINE; CYTOKINE; EPITOPE; FLT3 LIGAND PROTEIN; MACROPHAGE INFLAMMATORY PROTEIN 1; MEMBRANE PROTEIN; VIRUS DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR IMMUNITY; DENDRITIC CELL; DRUG EFFICACY; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNOGENICITY; IMMUNOTHERAPY; IN VIVO STUDY; INOCULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; VACCINIA VIRUS; VIRUS ENVELOPE; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CHEMISTRY; CHEMOTAXIS; CYTOLOGY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; METHODOLOGY; PLASMID; TIME;

ANIMALS; CANCER VACCINES; CHEMOTAXIS; CYTOKINES; DENDRITIC CELLS; DNA, VIRAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; HIV-1; IMMUNOHISTOCHEMISTRY; IMMUNOTHERAPY; MACROPHAGE INFLAMMATORY PROTEIN-1; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PLASMIDS; TIME FACTORS; VACCINES, DNA; VACCINIA VIRUS;

EID: 15244352727     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200422608     Document Type: Article

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