Radiation induces different changes in expression profiles of normal rectal tissue compared with rectal carcinoma

Virchows Archiv

Volumn 446, Issue 2, 2005, Pages 127-135

  Nagtegaal, I D ^a,b   Gaspar, C G S ^a   Peltenburg, L T C ^a   Marijnen, C A M ^a   Kapiteijn, E ^a   Van De Velde, C J H ^a   Fodde, R ^a   Van Krieken, J H J M ^b  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Apoptosis; Microarray; Radiotherapy; Rectal cancer

Indexed keywords

INTERLEUKIN 8; MASPIN;

ANALYTIC METHOD; APOPTOSIS; ARTICLE; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER SURGERY; CANCER TISSUE; CELL CYCLE; CELL SURVIVAL; COMPARATIVE STUDY; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE FUNCTION; GENETIC ANALYSIS; GENETIC VARIABILITY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IRRADIATION; MAJOR CLINICAL STUDY; MEDICAL LITERATURE; NUCLEOTIDE SEQUENCE; ONCOGENE; PREOPERATIVE PERIOD; PREOPERATIVE RADIOTHERAPY; PRIORITY JOURNAL; RADIATION; RECTUM; RECTUM CARCINOMA; SIGNAL TRANSDUCTION; TISSUE REPAIR; TUMOR CELL; UNINDEXED SEQUENCE;

APOPTOSIS; CELL ADHESION MOLECULES; CYTOKINES; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-8; KI-67 ANTIGEN; METALLOPROTEASES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PREOPERATIVE CARE; PROSPECTIVE STUDIES; RADIOTHERAPY, ADJUVANT; RECTAL NEOPLASMS; RECTUM; SERPINS;

EID: 15244350408     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00428-004-1160-8     Document Type: Article

References (39)

1. Agnihotri R, Crawford HC, Haro H, Matrisian LM, Havrda MC, Liaw L (2001) Osteopontin, a novel substrate for matrix metalloproteinase-3 (stromelysin-1) and matrix metalloproteinase-7 (matrilysin). J Biol Chem 276:28261-28267
2. Artuso M, Esteve A, Bresil H, Vuillaume M, Hall J (1995) The role of the Ataxia telangiectasia gene in the p53, WAF1/CIP1(p21)- and GADD45-mediated response to DNA damage produced by ionising radiation. Oncogene 11:1427-1435
3. Bus PJ, Nagtegaal ID, Verspaget HW, Lamers CBHW, van Krieken JHJM, Griffioen G (1999) Mesazaline-induced apoptosis of colorectal cancer: on the verge of a new chemopreventive era? Aliment Pharmacol Ther 13:1397-1402
4. Cuenca RE, Azizkhan RG, Haskill S (1992) Characterization of GRO alpha, beta and gamma expression in human colonic tumours: potential significance of cytokine involvement. Surg Oncol 1:323-329
5. de Fraipont F, Nicholson AC, Feige JJ, VanMeir EG (2001) Thrombospondins and tumor angiogenesis. Trends Mol Med 7:401-407
6. Ebara T, Mitsuhashi N, Saito Y, Akimoto T, Niibe H (1998) Change in E-cadherin expression after X-ray irradiation of a human cancer cell line in vitro and in vivo. Int J Radiat Oncol Biol Phys 41:669-674
7. Fornace AJ Jr (1992) Mammalian genes induced by radiation; activation of genes associated with growth control. Annu Rev Genet 26:507-526
8. Hockerfelt U, Henriksson R, Franzen L, Norrgard O, Forsgren S (1999) Irradiation induces marked immunohistochemical expression of vasoactive intestinal peptide in colonic mucosa of man. Dig Dis Sci 44:393-401
9. Hopeweel JW, Young CMA (1978) Changes in the microcirculation of normal tissues after irradiation. Int J Radiat Oncol Biol Phys 4:53-58
10. Jin H, Yang R, Awad TA, Wang F, Li W, Williams SP, Ogasawara A, Shimada B, Williams PM, de Feo G, Paoni NF (2001) Effects of early angiotensin- converting enzyme inhibition on cardiac gene expression after acute myocardial infarction. Circulation 103:736-742
11. Kapiteijn E, Marijnen CAM, Nagtegaal ID, Putter H, Steup WH, Wiggers T, Rutten HJT, Pahlman L, Glimelius B, van Krieken JHJM, Leer JWH, van de Velde CJH (2001) Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer. New Engl J Med 345:638-646
12. Kitahara O, Furukawa Y, Tanaka T, Kihara C, Ono K, Yanagawa R, Nita ME, Takagi T, Nakamura Y, Tsunoda T (2001) Alterations of gene expression during colorectal carcinogenesis revealed by cDNA microarrays after laser-capture microdissection of tumor tissues and normal epithelia. Cancer Res 61:3544-3549
13. Knebel A, Bohmer FD, Herrlich P (2000) Radiation-induced signal transduction. Methods Enzymol 319:255-272
14. Koch AE, Polverini PJ, Kunkel SL, Harlow LA, DiPietro LA, Elner VM, Elner SG, Strieter RM (1992) Interleukin-8 as a macrophage-derived mediator of angiogenesis. Science 258:1798-1801
15. Krishnan L, Krishnan EC, Jewell WR (1988) Immediate effect of irradiation on microvasculature. Int J Radiat Oncol Biol Phys 15:147-150
16. Kumar A, Collins H, van Tam J, Scholefield JH, Watson SA (2002) Effect of preoperative radiotherapy on matrilysin gene expression in rectal cancer. Eur J Cancer 38:505-510
17. Langberg CW, Hauer-Jensen M, Sung CC, Kane CJM (1994) Expression of fibrogenic cytokines in rat small intestine after fractionated irradiation. Radiother Oncol 32:29-36
18. Li Y, Jenkins CW, Nichols MA, Xiong Y (1994) Cell cycle expression and p53 regulation of the cyclin-dependent kinase inhibitor p21. Oncogene 9:2261-2268
19. Liu M, Dhanwada KR, Birt DF, Hecht S, Pelling JC (1994) Increase in p53 protein half-life in mouse keratinocytes following UV-B irradiation. Carcinogenesis 15:1089-1092
20. Marijnen CAM, Nagtegaal ID, Klein Kranenbarg E, Hermans J, van de Velde CJH, Leer JWH, van Krieken JHJM, Pathology Review Committee (2001) No downstaging after short-term preoperative radiotherapy in rectal cancer patients. J Clin Oncol 19:1976-1984
21. Marijnen CAM, Kapiteijn E, Nagtegaal ID, Mulder A, van de Velde CJH, Schrier PI, Peltenburg LTC, van Krieken JHJM (2002) p53 expression in rectal tissue after radiotherapy: remarkable long-term upregulation in normal mucosa versus extreme high frequency of functional loss in rectal carcinoma. Int J Radiation Oncology Biol Phys 52:720-728
22. Marijnen CAM, Kapiteijn E, van de Velde CJH, Martijn H, Steup WH, Wiggers T, Klein Kranenbarg E, Leer JWH (2002) Acute side effects and complications after short-term preoperative radiotherapy combined with total mesorectal excision in primary rectal cancer: report of a multicenter trial. J Clin Oncol 20:817-825
23. Nagtegaal ID, Klein Kranenbarg E, Hermans J, van de Velde CJH, van Krieken JHJM, Pathology Review Committee (2000) Pathology data in the central database of multicenter randomized trials need to be based on pathology reports and controlled by trained quality managers. J Clin Oncol 18:1771-1779
24. Nagtegaal ID, Marijnen CAM, Klein Kranenbarg E, Mulder A, Hermans J, van de Velde CJH, van Krieken JHJM (2001) Local and distant recurrences in rectal cancer patients are predicted by the nonspecific immune response; specific immune response has only systemic effect - a histopathological and immunohistochemical study. BMC Cancer 1:7
25. Nagtegaal ID, Marijnen CAM, Klein Kranenbarg E, Mulder A, Hermans J, van de Velde CJH, van Krieken JHJM (2002) Short-term preoperative radiotherapy interferes with the determination of pathological parameters in rectal cancer. J Pathol 197:20-27
26. Ng IO, Lam KY, Ng M, Kwong DL, Sham JS (1998) Expression of P-glycoprotein, a multidrug-resistance gene product, is induced by radiotherapy in patients with oral squamous cell carcinoma. Cancer 83:851-857
27. Notterman DA, Alon U, Sierk AJ, Levine AJ (2001) Transcriptional gene expression profiles of colorectal adenoma, adenocarcinoma, and normal tissue examined by oligonucleotide arrays. Cancer Res 61:3124-3130
28. Paris F, Fuks Z, Kang A, Capodieci P, Juan G, Ehleiter D, Haimovitz-Friedman A, Cordon-Cardo C, Kolesnick R (2001) Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice. Science 293:293-297
29. Renehan AG, Bach SP, Potten CS (2001) The relevance of apoptosis for cellular homeostasis and tumorigenesis in the intestine. Can J Gastroenterol 15:166-176
30. Roberts AB, Sporn MB, Assoian RK, Smith JM, Roche NS, Wakefield LM, Heine UI, Liotta LA, Falanga V, Kehrl JH (1986) Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc Natl Acad Sci U S A 83:4167-4171
31. Rosen EM, Fan S, Rockwell S, Goldberg ID (1999) The molecular and cellular basis of radiosensitivity: implications for understanding how normal tissues and tumors respond to therapeutic radiation. Cancer Invest 17:56-72
32. Schmidt-Ullrich RK, Dent P, Mikkelsen RB, Valerie K (2000) Signal transduction and cellular radiation responses. Radiat Res 153:245-257
33. Seidita G, Polizzi D, Costanzo G, Costa S, Di Leonardo A (2000) Differential gene expression in p53-mediated G(1) arrest of human fibroblasts after gamma-irradiation or N-phosphoacetyl-L-aspartate treatment. Carcinogenesis 21:2203-2210
34. Thiagarajah JR, Gourmelon P, Griffiths NM, Lebrun F, Naftalin RJ, Pedley KC (2000) Radiation induced cytochrome c release causes loss of rat colonic fluid absorption by damage to crypts and pericryptal myofibroblasts. Gut 47:675-684
35. Thykjaer T, Workman C, Kruhoffer M, Demtroder K, Wolf H, Andersen LD, Frederiksen CM, Knudsen S, Orntoft TF (2001) Identification of gene expression patterns in superficial and invasive human bladder cancer. Cancer Res 61:2492-2499
36. Wang H, Chakrabarty S (2001) Requirement of protein kinase Calpha, extracellular matrix remodeling, and cell-matrix interaction for transforming growth factor beta-regulated expression of E-cadherin and catenins. J Cell Physiol 187:188-195
37. Xiao G, Chicas A, Olivier M, Taya Y, Tyagi S, Kramer FR, Bargonetti J (2000) A DNA damage signal is required for p53 to activate gadd45. Cancer Res 60:1711-1719
38. Yamakawa T, Kurosawa N, Kadomatsu K, Matsui T, Itoh K, Maeda N, Noda M, Muramatsu T (1999) Levels of expression of pleiotrophin and protein tyrosine phosphatase zeta are decreased in human colorectal cancers. Cancer Lett 135:91-96
39. Zou Z, Gao C, Nagaich AK, Connell T, Saito S, Moul JW, Seth P, Appella E, Srivastava S (2000) p53 regulates the expression of the tumor suppressor gene maspin. J Biol Chem 275:6051-6054