Ligands for peroxisome proliferator-activated receptor gamma have potent antitumor effect against human renal cell carcinoma

Urology

Volumn 65, Issue 3, 2005, Pages 594-599

  Yuan, Jinyang ^a   Takahashi, Atsushi ^a   Masumori, Naoya ^a   Uchida, Kohsuke ^a   Hisasue, Shin Ichi ^a   Kitamura, Hiroshi ^a   Itoh, Naoki ^a   Tsukamoto, Taiji ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ANGIOGENIC FACTOR; ANTINEOPLASTIC AGENT; BROMINE DERIVATIVE; DIMER; FIBROBLAST GROWTH FACTOR; LIGAND; LIPOCORTIN 5; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIOGLITAZONE; RETINOID X RECEPTOR; VASCULOTROPIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; CANCER CELL CULTURE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; KIDNEY CARCINOMA; NICK END LABELING; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW;

EID: 15244347893     PISSN: 00904295     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.urology.2004.10.019     Document Type: Article

References (28)

1. A.C. Novick, S.C. Campbell Renal tumors P.C. Walsh A.B. Retik E.D. Vaughan Jr Campbell's Urology 8th ed 2002 WB Saunders Philadelphia 2672 2731
2. D.J. Mangelsdorf, C. Thummel, M. Beato The nuclear receptor superfamily the second decade Cell 83 1995 835 839
3. B. Desvergne, W. Wahli Peroxisome proliferator-activated receptors nuclear control of metabolism Endocr Rev 20 1999 649 688
4. S.A. Kliewer, K. Umesono, D.J. Noonan Convergence of 9-cis retinoic acid and peroxisome proliferator signaling pathways through heterodimer formation of their receptors Nature 358 1992 771 774
5. C.N. Palmer, M.H. Hsu, H.J. Griffin Novel sequence determinants in peroxisome proliferator signaling J Biol Chem 270 1995 16114 16121
6. C. Jiang, A.T. Ting, B. Seed PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines Nature 391 1998 82 86
7. P. Tontonoz, L. Nagy, J.G. Alvarez PPAR gamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL Cell 93 1998 241 252
8. B.M. Spiegelman PPAR gamma in monocytes less pain, any gain? Cell 93 1998 153 155
9. H.P. Koeffler Peroxisome proliferator-activated receptor γ and cancers Clin Cancer Res 9 2003 1 9
10. T. Kubota, K. Koshizuka, E.A. Williamson Ligand for peroxisome proliferator-activated receptor γ (troglitazone) has potent antitumor effect against human prostate cancer both in vitro and in vivo Cancer Res 58 1998 3344 3352
11. Y.F. Guan, Y.H. Zhang, R.M. Breyer Expression of peroxisome proliferator-activated receptor γ (PPARγ) in human transitional bladder cancer and its role in inducing cell death Neoplasia 1 1999 330 339
12. X. Xin, S. Yang, J. Kowalski Peroxisome proliferator-activated receptor γ ligands are potent inhibitors of angiogenesis in vitro and in vivo J Biol Chem 274 1999 9116 9121
13. D. Panigrahy, S. Singer, L.Q. Shen PPAR γ ligands inhibit primary tumor growth and metastasis by inhibiting angiogenesis J Clin Invest 110 2002 923 932
14. A. Takahashi, H. Sasaki, S.J. Kim Markedly increased amounts of messenger RNAs for vascular endothelial growth factor and placenta growth factor in renal cell carcinoma associated with angiogenesis Cancer Res 54 1994 4233 4237
15. N. Miyao, T. Tsukamoto, Y. Kumamoto Establishment of three human renal cell carcinoma cell lines (SMKT-R-1, SMKT-R-2, and SMKT-R-3) and their characters Urol Res 17 1989 317 324
16. N. Otani, T. Tsukamoto, Y. Kumamoto Study on in vitro invasive potential of renal cell carcinoma cell lines and effect of growth factors (EGF and TGF-β1) Jpn J Urol 82 1991 613 619
17. H. Sasamura, A. Takahashi, J. Yuan Anti-proliferative and anti-angiogenic activities of genistein in human renal cell carcinoma Urology 64 2004 389 393
18. K. Inoue, Y. Kawahito, Y. Tsubouchi Expression of peroxisome proliferator-activated receptor gamma in renal cell carcinoma and growth inhibition by its agonists Biochem Biophys Res Commun 287 2001 727 732
19. M. Toyoda, H. Takagi, N. Horiguchi A ligand for peroxisome proliferator-activated receptor gamma inhibits cell growth and induces apoptosis in human liver cancer cells Gut 50 2002 563 567
20. K. Yoshizawa, D.P. Cioca, S. Kawa Peroxisome proliferator-activated receptor gamma ligand troglitazone induces cell cycle arrest and apoptosis of hepatocellular carcinoma cell lines Cancer 95 2002 2243 2251
21. G. Eibl, M.N. Wente, H.A. Reber Peroxisome proliferator-activated receptor gamma induces pancreatic cancer cell apoptosis Biochem Biophys Res Commun 287 2001 522 529
22. M. Nagamine, T. Okumura, S. Tanno PPARγ ligand-induced apoptosis through a p53-dependent mechanism in human gastric cancer cells Cancer Sci 4 2003 338 343
23. KiP1 in human pancreatic carcinoma cells Cancer Res 60 2000 5558 5564
24. M.A. Rumi, H. Sato, S. Ishihara Growth inhibition of esophageal squamous carcinoma cells by peroxisome proliferator-activated receptor gamma ligands J Lab Clin Med 140 2002 17 26
25. 2 J Biol Chem 274 1999 17042 17048
26. A. Jozkowicz, J. Dulak, E. Piatkowska Ligands of peroxisome proliferator-activated receptor-gamma increase the generation of vascular endothelial growth factor in vascular smooth muscle cells and in macrophages Acta Biochim Pol 47 2000 1147 1157
27. S. Fauconnet, I. Lascombe, E. Chabannes Differential regulation of vascular endothelial growth factor expression by peroxisome proliferator- activated receptors in bladder cancer cells J Biol Chem 277 2002 23534 23543
28. 2 induces vascular endothelial growth factor in the hormone-independent prostate cancer cell line PC-3 and the urinary bladder carcinoma cell line 5637 Int J Oncol 21 2002 915 920