Dilemmas of contemporary epilepsy pharmacotherapy;Dileme suvremene farmakoterapije epilepsije

Acta Medica Croatica

Volumn 59, Issue 1, 2005, Pages 1-6

  Bielen, Ivan ^a  

^a Croatian Academy of Medical Sciences   (Croatia)

Author keywords

Clinical trial; Epilepsy; Guidelines; Therapy

Indexed keywords

ANTICONVULSIVE AGENT;

ADD ON THERAPY; ANTICONVULSANT THERAPY; CLINICAL FEATURE; CLINICAL TRIAL; DRUG BIOAVAILABILITY; DRUG PREFERENCE; EPILEPSY; EVIDENCE BASED MEDICINE; HUMAN; LICENSING; PRACTICE GUIDELINE; REVIEW; SEIZURE; TREATMENT OUTCOME;

ANTICONVULSANTS; EPILEPSY; EVIDENCE-BASED MEDICINE; HUMANS; PRACTICE GUIDELINES;

EID: 15244347190     PISSN: 13300164     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (36)

1. Matson RH, Cramer JA, Collins JF i sur. Comparison of carbamazepine, phenobarbital, phenytoin, and primidon in partial and secondarily generalized tonic-clonic seizures. N Engl J Med 1985; 313: 145-51.
2. De Silva M, MacArdle B, McGovas M i sur. Randomised comparative monotherapy trial of phenobarbitone, phenytoin, carbamazepine and sodium valproate for newly diagnosed childhood epilepsy. Lancet 1996; 347: 709-13.
3. Heller AJ, Chesterman P, Elwes RD i sur. Phenobarbitone, phenytoin, carbamazepine, or sodium valproate for newly diagnosed adult epilepsy: a randomized comparative monotherapy study. J Neurol Neurosurg Psychiatry 1995; 58: 44-50.
4. Mattson RH. Efficacy and adverse effects of established and new antiepileptic drugs. Epilepsia 1995; 36 (Suppl 2): 13-26.
5. Shorvon SD. The choice of drugs and approach to drug treatments in partial epilepsy. U: Shorvon SD, Perucca E, Fish D, Dodson E, ur. The treatment of epilepsy. Massachusetts: Blackwell Science, 2004, 317-33.
6. Marson AG, Kadir ZA, Mutton JL, Chadwick DW. The new antiepileptic drugs: a systematic review of their efficacy and tolerability. Epilepsia 1997; 38: 859-80.
7. Elferink JA, Van Zwieten BJ. New antiepileptic drugs: Analysis of number needed to treat shows differences between drugs studied. BMJ 1997; 27: 205-13.
8. Lessafre E, Boon P, Pledger GW. The value of number-needed-to-treat method in antiepileptic drug trials. Epilepsia 2000; 41: 440-6.
9. Walker MC, Sander JWAS. Difficulties in extrapolating from clinical trial dana to clinical practice: The case of antiepileptic drugs. Neurology 1997; 49: 333-7.
10. Perucca E. Drugs under clinical trial. U: Eadie MJ, Vajda FJE, ur. Antiepileptic drugs farmacology and therapeutics, Handbook of experimental farmacology, Vol 138. Berlin: Springer Verlag, 1999: 515-51.
11. Perucca E. What can we learn from clinical trials of anticonvulsant drugs in epilepsy? Eur J Pain 2002; 6 (suppl. A): 35-44.
12. Perucca E, Torbjörn T. Monotherapy trials with the new antipileptic drugs: Study designs, practical relevance and ethical implications. Epilepsy Res 1999; 33: 247-62.
13. Perucca E. Current trends in antiepileptic drug therapy. Epilepsia 2003; 44 (Suppl. 4): 41-7.
14. Birbeck GL, Hays RD, Cui X, Vickrey BG. Seizure reduction and quality of life improvements in people with epilepsy. Epilepsia 2002; 43: 535-8.
15. Walker MC, Sander JWAS. The impact of new antiepileptic drugs on the prognosis of epilepsy: seizure freedom should be the ultimate goal. Neurology 1996; 46: 912-14.
16. Kwan P, Brodie MJ. Clinical trials of antiepilepic medications in newly diagnosed patients with epilepsy. Neurology 2003; 60 (Suppl 4): 2-12.
17. Scottish Intercollegiate Guidlines Network (SIGN). Diagnosis and management of epilepsy in adults. www.sign.ac.uk
18. Ben-Menachem E, Scheepers B, Stodieck S. Epilepsy: from consensus to daily practice. Acta Neurol Scand 2003; 108 (suppl. 180): 5-15.
19. American Academy of Neurology. Quality Standards Subcomitee.: management issues for women with epilepsy. Report of the Quality Standards Subcomitee of the American Academy of Neurology. Epilepsia 1998; 39: 1226-31.
20. American Academy of Pediatrics. Committee on Quality Improvement. Subcommittee on Febrile Seizures. Practice parameter: longterm treatment of the child with simple febrile seizures. Pediatrics 1999; 103: 1307-9.
21. French JA, Kanner AM, Bautista J i sur. Efficacy and tolerability of the new antiepileptic drugs I: Treatment of new onset epilepsy - Report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology 2004; 62: 1252-12.
22. French JA, Kanner AM, Bautista J i sur. Efficacy and tolerability of the new antiepileptic drugs II: Treatment of refractory epilepsy - Report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology 2004; 62: 1261-73.
23. Bielen I, Cvitanović-Šojat Lj, Matek P, Planjar-Prvan M. Increase of classical antiepileptic drug utilization in Croatia during the process of introducing the new generation of drugs. Coll Antropol 2003; 27: 617-22.
24. Davis J, Roberts R, Davidson DL i sur. Implementation strategies for a Scottish national epilepsy guideline in primary care: results of the Tayside Implementation of Guidelines in Epilepsy Randomized (TIGER) trial. Epilepsia 2004; 45: 28-34.
25. Chiron C, Dumas C, Jambaque I, Mumford J, Dulac O. Randomized trial comparing vigabatrin and hydrocortisone in infantile spasms due to tuberous sclerosis. Epilepsy Res 1997; 26: 389-95.
26. Chiron C, Marchand MC, Tran A i sur. Stiripentol in severe myoclonic epilepsy in infancy: a randomised placebo-controlled syndrome dedicated trial. STICLO study group. Lancet 2000; 356: 1638-42.
27. Zara F. Genetic counselling in epilepsy. U: Shorvon SD, Perucca E, Fish D, Dodson E, ur. The treatment of epilepsy. Massachusetts: Blackwell Science, 2004, 290-306.
28. Annegers JF. Epidemiology of epilepsy. U: Wyllie E, ur. The treatment of epilepsy: principles and praxis, 3rd ed. Philadelphia: Lippincott Williams & Wilkins, 2001, 131-8.
29. Tallis R, Boon P, Perucca E, Stephen L. Epilepsy in elderly people: management issues. Epileptic Disord 2002; 4 (Suppl 2): 33-9.
30. Drury I, Beydoun A. Seizures and epilepsy in the elderly revisited. Arch Intern Med 1998; 158: 99-100.
31. Cameron H, Macphee GJ. Anticonvulsant therapy in the elderly - a need for placebo controlled trials. Epilepsy Res 1995; 21: 149-57.
32. Brodie MJ, Overstall P, Giorgi I. And the lamotrigine elderly study group. Multi-centre, double-blind comparison between lamotrigine and carbamazepine in elderly patients with newly diagnosed epilepsy. Epilepsy Res 1999; 37: 81-7.
33. Montouris G. Gabapentin exposure in human pregnancy: results from the Gabapentin Pregnancy Registry. Epilepsy Behav 2003; 4: 310-17.
34. Morrell MJ. Reproductive and metabolic disorders in women with epilepsy. Epilepsia 2003; 44(Suppl 4): 11-20.
35. Wide K, Winbladh B, Kallen B. Major malformations in infants exposed to antiepileptic drugs in utero, with emphasis on carbamazepine and valproic acid: a nation-wide, population-based register study. Acta Paediatr 2004; 93: 174-76.
36. Tennis P, Eldridge RR. Preliminary results on pregnancy outcomes in women using lamotrigine. Epilepsia 2002; 43: 1161-7.