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Volumn 7, Issue 5, 2005, Pages 851-853

Microwave-assisted regioselective addition of P(O)-H bonds to alkenes without added solvent or catalyst

Author keywords

[No Author keywords available]

Indexed keywords

ALKENE DERIVATIVE; ALKYNE DERIVATIVE; HYDROGEN; PHOSPHINE DERIVATIVE; PHOSPHINE OXIDE DERIVATIVE; PHOSPHORUS; SOLVENT;

EID: 15044353090     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol0474047     Document Type: Article
Times cited : (127)

References (17)
  • 15
    • 15044348402 scopus 로고    scopus 로고
    • note
    • In a typical reaction, a new reactor vial (10 mL) was charged with the phosphine oxide or phosphinate (0.023-0.025 mmol) and a new magnetic stirring bar. The new equipment was used to prevent metal contamination from other reactions. The vial was evacuated and refilled with nitrogen before addition of the alkene (1 equiv). In the case of divinyl sulfone, 0.5 equiv of the alkene was used. The vial was heated in the microwave for the desired time at 120-140°C. After cooling to room temperature, the purity of the product was determined by GC and multinuclear NMR spectroscopy. When needed, the products were purified by trituration with an appropriate solvent or by column chromatography.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.