Study of the in vivo and in vitro cardiovascular effects of a hydralazine-like vasodilator agent (HPS-10) in normotensive rats

British Journal of Pharmacology

Volumn 121, Issue 8, 1997, Pages 1627-1636

  Orallo, Francisco ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

Bradycardia; Conscious and anaesthetized normotensive rats; HPS 10; Hydrazinopyridazines; Hypotension; Rat aorta; Rat atria; Vasodilator agent; Whole cell clamped rat aortic myocytes

Indexed keywords

6 HYDRAZINO 4 MORPHOLINOMETHYL 6 PHENYLPYRIDAZINE; ANGIOTENSIN; BARIUM ION; CALCIUM 45; CALCIUM ION; HYDRALAZINE; NICOTINE; NORADRENALIN; POTASSIUM ION; PROPRANOLOL; UNCLASSIFIED DRUG; VASODILATOR AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; CALCIUM TRANSPORT; CARDIOVASCULAR EFFECT; CHRONOTROPISM; CONTROLLED STUDY; CULTURE MEDIUM; DIASTOLIC BLOOD PRESSURE; DOSE RESPONSE; DRUG MEGADOSE; HEART RATE; INOTROPISM; INTRAVENOUS DRUG ADMINISTRATION; ION CURRENT; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE FIBER; SYSTOLIC BLOOD PRESSURE; TACHYCARDIA; VASCULAR SMOOTH MUSCLE;

ANGIOTENSIN II; ANIMALS; BLOOD PRESSURE; CALCIUM; HEART RATE; HYDRAZINES; MALE; MICE; MYOCARDIAL CONTRACTION; NOREPINEPHRINE; PYRIDAZINES; RATS; RATS, WISTAR; VASOCONSTRICTION; VASODILATOR AGENTS;

EID: 0030800195     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701314     Document Type: Article

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