Acute hepatitis C: Diagnosis and management

Journal of Hepatology

Volumn 42, Issue SUPPL. 1, 2005, Pages

  Mondelli, Mario U ^a   Cerino, Antonella ^a   Cividini, Agostino ^a  

^a UNIVERSITY OF PAVIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ANTIVIRUS AGENT; IMMUNOSUPPRESSIVE AGENT; RIBAVIRIN;

CLINICAL TRIAL; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; IMMUNOBIOLOGY; IMMUNOSUPPRESSIVE TREATMENT; PRIORITY JOURNAL; REVIEW; SEXUAL TRANSMISSION; SIDE EFFECT; T LYMPHOCYTE; VIRUS REPLICATION;

EID: 14944342985     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2004.10.017     Document Type: Review

References (81)

1. M. Houghton C. Hagedorn C. Rice The hepatitis C viruses 2000 Springer Berlin 327
2. H.J. Alter, C. Conry-Cantelena, J. Melpolder, D. Tan, M. Van Raden, and D. Herion Hepatitis C in asymptomatic blood donors Hepatology 26 1997 29S 33S
3. D.L. Thomas, J. Astemborski, R.M. Rai, F.A. Anania, M. Schaeffer, and N. Galai The natural history of hepatitis C virus infection: host, viral and environmental factors JAMA 284 2000 450 456
4. L.B. Seeff, F.B. Hollinger, H.J. Alter, E.C. Wright, C.M. Cain, and Z.J. Buskell Long-term mortality and morbidity of transfusion-associated non-A, non-B and type C hepatitis; a National Heart, Lung and Blood Institute collaborative study Hepatology 33 2001 455 463
5. M.J. Alter, H.S. Margolis, K. Krawczynski, F.N. Judson, A. Mares, and W.J. Alexander The natural history of community-acquired hepatitis C in the United States N Engl J Med 327 1992 1899 1905
6. A. Locasciulli, M. Testa, P. Pontisso, L. Benvegnu, D. Fraschini, and A. Corbetta Prevalence and natural history of hepatitis C infection in patients cured of childhood leukemia Blood 90 1997 4628 4633
7. E. Kenny-Walsh, and for the Irish Hepatology Research Group Clinical outcomes after hepatitis C infection from contaminated anti-D immune globulin N Engl J Med 340 1999 1228 1233
8. M. Wiese, F. Berr, M. Lafrenz, H. Porst, and V. Olsen Low frequency of cirrhosis in a hepatitis C (genotype 1b) single-source outbreak in Germany: a 20-year multicenter study Hepatology 32 2000 91 96
9. M. Vogt, T. Lang, G. Frosner, C. Klingler, A.F. Sendl, and A. Zeller Prevalence and clinical outcome of hepatitis C infection in children who underwent cardiac surgery before the implementation of blood-donor screening N Engl J Med 341 1999 866 870
10. A.J. Rodger, S. Roberts, A. Lanigan, S. Bowden, T. Brown, and N. Crofts Assessment of long-term outcomes of community-acquired hepatitis C infection in a cohort with sera stored from 1971-1975 Hepatology 32 2000 582 587
11. A. Larghi, M. Zuin, A. Crosignani, M.L. Ribero, C. Pipia, and P.M. Battezzati Outcome of an outbreak of acute hepatitis C among healthy volunteers participating in pharmokinetics studies Hepatology 36 2002 993 1000
12. E. Bianco, T. Stroffolini, E. Spada, A. Szklo, F. Marzolini, and P. Ragni Case fatality rate of acute viral hepatitis in Italy: 1995-2000. An update Dig Liver Dis 35 2003 404 408
13. M.U. Mondelli Natural history of hepatitis C virus infection J Biol Regul Homeost Agents 17 2003 128 132
14. M.J. Koziel, D.K. Wong, D. Dudley, M. Houghton, and B.D. Walker Hepatitis C virus-specific cytolytic T lymphocyte and T helper cell responses in seronegative persons J Infect Dis 176 1997 859 866
15. P. Scognamiglio, D. Accapezzato, M.A. Casciaro, A. Cacciani, M. Artini, and G. Bruno Presence of effector CD8+ T cells in hepatitis C virus-exposed healthy seronegative donors J Immunol 162 1999 6681 6689
16. M.T. Shata, N. Tricoche, M. Perkus, D. Tom, B. Brotman, and P. McCormack Exposure to low infective doses of HCV induces cellular immune responses without consistently detectable viremia or seroconversion in chimpanzees Virology 314 2003 601 616
17. J.J. Post, Y. Pan, A.J. Freeman, C.E. Harvey, P.A. White, and P. Palladinetti Clearance of hepatitis C viremia associated with cellular immunity in the absence of seroconversion in the hepatitis C incidence and transmission in prisons study cohort J Infect Dis 189 2004 1846 1855
18. A. Bertoletti, and C. Ferrari Kinetics of the immune response during HBV and HCV infection Hepatology 38 2003 4 13
19. R. Thimme, D. Oldach, K.M. Chang, C. Steiger, S.C. Ray, and F.V. Chisari Determinants of viral clearance and persistence during acute hepatitis C virus infection J Exp Med 194 2001 1395 1406
20. R. Thimme, J. Bukh, H.C. Spangenberg, S. Wieland, J. Pemberton, and C. Steiger Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease Proc Natl Acad Sci USA 99 2002 15661 15668
21. A.M. Prince, J.M. Pawlotsky, A. Soulier, L. Tobler, B. Brotman, and W. Pfahler Hepatitis C virus replication kinetics in chimpanzees with self-limited and chronic infections J Viral Hepatol 11 2004 236 242
22. J.T. Gerlach, H.M. Diepolder, R. Zachoval, N.H. Gruener, M.C. Jung, and A. Ulsenheimer Acute hepatitis C: high rate of both spontaneous and treatment-induced viral clearance Gastroenterology 125 2003 80 88
23. T. Santantonio, E. Sinisi, A. Guastadisegni, C. Casalino, M. Mazzola, and A. Gentile Natural course of acute hepatitis C: a long-term prospective study Dig Liver Dis 35 2003 104 113
24. E. Spada, A. Mele, A. Berton, L. Ruggeri, L. Ferrigno, and A.R. Garbuglia Multi-specific T-cell response and negative HCV RNA tests during acute HCV infection are early prognostic factors of spontaneous clearance Gut 53 2004 1673 1681
25. P. Farci, A. Shimoda, A. Coiana, G. Diaz, G. Peddis, and J.C. Melpoder The outcome of acute hepatitis C predicted by the evolution of the viral quasispecies Science 288 2000 339 344
26. M.U. Mondelli, A. Cerino, A. Lisa, S. Brambilla, L. Segagni, and A. Cividini Antibody responses to hepatitis C virus hypervariable region 1: evidence for cross-reactivity and immune-mediated sequence variation Hepatology 30 1999 537 545
27. J.C.L. Booth, U. Kumar, D. Webster, J. Monjardino, and H.C. Thomas Comparison of the rate of sequence variation in the hypervariable region of E2/NS1 region of hepatitis C virus in normal and hypogammaglobuolinemic patients Hepatology 26 1998 223 227
28. H.M. Diepolder, R. Zachoval, R.M. Hoffmann, E.A. Wierenga, T. Santantonio, and M.C. Jung Possible mechanism involving T-lymphocyte response to nonstructural protein 3 in viral clearance in acute hepatitis C infection Lancet 346 1995 1006 1007
29. C. Ferrari, A. Valli, L. Galati, A. Penna, P. Scaccaglia, and T. Giuberti T-cell response to structural and nonstructural hepatitis C virus antigens in persistent and self-limited hepatitis C virus infections Hepatology 19 1994 286 295
30. G. Missale, R. Bertoni, V. Lamonaca, A. Valli, M. Massari, and C. Mori Different clinical behaviours of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response J Clin Invest 98 1996 706 714
31. J.T. Gerlach, H.M. Diepolder, M.C. Jung, N.H. Gruener, W.W. Schraut, and R. Zachoval Recurrence of hepatitis C virus after loss of virus-specific CD4(+) T-cell response in acute hepatitis C Gastroenterology 117 1999 933 941
32. N.H. Gruner, T.J. Gerlach, M.C. Jung, H.M. Diepolder, C.A. Schirren, and W.W. Schraut Association of hepatitis C virus-specific CD8+ T cells with viral clearance in acute hepatitis C J Infect Dis 181 2000 1528 1536
33. S.M. Kamal, A. Ismail, C.S. Graham, Q. He, J.W. Rasenack, and T. Peters Pegylated interferon alpha therapy in acute hepatitis C: relation to hepatitis C virus-specific T cell response kinetics Hepatology 39 2004 1721 1731
34. F. Rahman, T. Heller, Y. Sobao, E. Mizukoshi, M. Nascimbeni, and H. Alter Effects of antiviral therapy on the cellular immune response in acute hepatitis C Hepatology 40 2004 87 97
35. S. Tsai, Y. Liaw, M. Chen, C. Huang, and G.C. Kuo Detection of type 2-like T-helper cells in hepatitis C virus infection: implications for hepatitis C virus chronicity Hepatology 25 1997 449 458
36. H. Wedemeyer, X.S. He, M. Nascimbeni, A.R. Davis, H.B. Greenberg, and J.H. Hoofnagle Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection J Immunol 169 2002 3447 3458
37. S. Cooper, A.L. Erikson, E.J. Adams, J. Kansopon, A.J. Weiner, and D.Y. Chien Analysis of a successful immune response against hepatitis C virus Immunity 10 1999 439 449
38. M. Cucchiarini, A.R. Kammer, B. Grabscheid, H.M. Diepolder, T.J. Gerlach, and N. Gruner Vigorous peripheral blood cytotoxic T cell response during the acute phase of hepatitis C virus infection Cell Immunol 203 2000 111 123
39. K.M. Chang, N.H. Gruener, S. Southwood, J. Sidney, G.R. Pape, and F.V. Chisari Identification of HLA-A3 and -B7-restricted CTL response to hepatitis C virus in patients with acute and chronic hepatitis C J Immunol 162 1999 1156 1164
40. S. Urbani, C. Boni, G. Missale, G. Elia, C. Cavallo, and M. Massari Virus-specific CD8+ lymphocytes share the same effector-memory phenotype but exhibit functional differences in acute hepatitis B and C J Virol 76 2002 12423 12434
41. M.K. Large, D.J. Kittlesen, and Y.S. Hahn Suppression of host immune response by the core protein of hepatitis C virus: possible implications for hepatitis C virus persistence J Immunol 162 1999 931 938
42. D.J. Kittlesen, K.A. Chianese-Bullock, Z.Q. Yao, T.J. Braciale, and Y.S. Hahn Interaction between complement receptor gC1qR and hepatitis C virus core protein inhibits T-lymphocyte proliferation J Clin Invest 106 2000 1239 1249
43. M. Matsumoto, T.Y. Hsieh, N. Zhu, T. VanArsdale, S.B. Hwang, and K.S. Jeng Hepatitis C virus core protein interacts with the cytoplasmic tail of lymphotoxin-beta receptor J Virol 71 1997 1301 1309
44. C.M. Chen, L.R. You, L.H. Hwang, and Y.H. Lee Direct interaction of hepatitis C virus core protein with the cellular lymphotoxin-beta receptor modulates the signal pathway of the lymphotoxin-beta receptor J Virol 71 1997 9417 9426
45. N. Zhu, A. Khoshnan, R. Schneider, M. Matsumoto, G. Dennert, and C. Ware Hepatitis C virus core protein binds to the cytoplasmic domain of tumor necrosis factor (TNF) receptor 1 and enhances TNF-induced apoptosis J Virol 72 1998 3691 3697
46. R.B. Ray, K. Meyer, R. Steele, A. Shrivastava, B.B. Aggarwal, and R. Ray Inhibition of tumor necrosis factor (TNF-alpha)-mediated apoptosis by hepatitis C virus core protein J Biol Chem 273 1998 2256 2259
47. C.S. Hahn, Y.G. Cho, B.S. Kang, I.M. Lester, and Y.S. Hahn The HCV core protein acts as a positive regulator of fas-mediated apoptosis in a human lymphoblastoid T cell line Virology 276 2000 127 137
48. A. Bergqvist, S. Sundstrom, L.Y. Dimberg, E. Gylfe, and M.G. Masucci The hepatitis C virus core protein modulates T cell responses by inducing spontaneous and altering T-cell receptor-trigged Ca2+ oscillations J Biol Chem 278 2003 18877 18883
49. D. Accapezzato, V. Francavilla, P. Rawson, A. Cerino, A. Cividini, and M.U. Mondelli Subversion of effector CD8+ T cell differentiation in acute hepatitis C virus infection: the role of the virus Eur J Immunol 34 2004 438 446
50. T.N. Pham, S.A. MacParland, P.M. Mulrooney, H. Cooksley, N.V. Naoumov, and T.I. Michalak Hepatitis C virus persistence after spontaneous or treatment-induced resolution of hepatitis C J Virol 78 2004 5867 5874
51. S. Vento, F. Cainelli, and M.S. Longhi Reactivation of replication of hepatitis B and C viruses after immunosuppressive therapy: an unresolved issue Lancet Oncol 3 2002 333 340
52. T. Pollicino, G. Squadrito, G. Cerenzia, I. Cacciola, G. Raffa, and A. Craxi Hepatitis B virus maintains its pro-oncogenic properties in the case of occult HBV infection Gastroenterology 126 2004 102 110
53. M.J. Alter Prevention of spread of hepatitis C Hepatology 36 2002 S93 S98
54. A. Mele, E. Spada, L. Sagliocca, P. Ragni, M.E. Tosti, and G. Gallo Risk of parenterally transmitted hepatitis following exposure to surgery or other invasive procedures: results from the hepatitis surveillance system in Italy J Hepatol 35 2001 284 289
55. E.A. Roberts, and L. Yeung Maternal-infant transmission of hepatitis C virus infection Hepatology 36 2002 S106 S113
56. C. Velati, L. Romano, L. Baruffi, M. Pappalettera, V. Carreri, and A.R. Zanetti Residual risk of transfusion-transmitted HCV and HIV infections by antibody-screened blood in Italy Transfusion 42 2002 989 993
57. Anonymous National Institutes of Health Consensus Development Conference Panel statement: management of hepatitis C Hepatology 26 1997 2S 10S
58. N.A. Terrault Sexual activity as a risk factor for hepatitis C Hepatology 36 2002 S99 S105
59. J.M. Pawlotsky Use and interpretation of virological tests for hepatitis C Hepatology 36 2002 S65 S73
60. J.R. Orland, T.L. Wright, and S. Cooper Acute hepatitis C Hepatology 33 2001 321 327
61. A. Cividini, A. Cerino, A. Muzzi, M. Furione, C. Rebucci, and L. Segagni Kinetics and significance of serum hepatitis C virus core antigen in patients with acute hepatitis C J Clin Microbiol 41 2003 2144 2146
62. J.T. Stapleton GB virus type C/Hepatitis G virus Semin Liver Dis 23 2003 137 148
63. N.V. Naoumov TT virus - highly prevalent, but still in search of a disease J Hepatol 33 2000 157 159
64. A. Sagir, O. Kirschberg, T. Heintges, A. Erhardt, and D. Haussinger SEN virus infection Rev Med Virol 14 2004 141 148
65. D.A. Relman, and S. Falkow A molecular perspective of microbial pathogenicity G.L. Mandell J.E. Bennett R. Dolin Principles and Practice of Infectious Diseases 5th ed 2000 Churchill Livingstone New York 2 13
66. J. Wiegand, E. Jackel, M. Cornberg, H. Hinrichsen, M. Dietrich, and J. Kroeger Long-term follow-up after successful interferon therapy of acute hepatitis C Hepatology 40 2004 98 107
67. M.U. Mondelli Monitoring response to antiviral treatment by serum hepatitis C virus core antigen: too early to take shortcuts? J Hepatol 40 2004 536 538
68. M. Lehmann, M.F. Meyer, M. Monazahian, H.L. Tillmann, M.P. Manns, and H. Wedemeyer High rate of spontaneous clearance of acute hepatitis C virus genotype 3 infection J Med Virol 73 2004 387 391
69. H. Hofer, T. Watkins-Riedel, O. Janata, E. Penner, H. Holzmann, and P. Steindl-Munda Spontaneous viral clearance in patients with acute hepatitis C can be predicted by repeated measurements of serum viral load Hepatology 37 2003 60 64
70. E. Jaeckel, M. Cornberg, H. Wedemeyer, T. Santantonio, J. Mayer, and M. Zankel Treatment of acute hepatitis C with interferon alfa-2b N Engl J Med 345 2001 1452 1457
71. W. Vogel, I. Graziadei, F. Umlauft, C. Datz, F. Hackl, and S. Allinger High-dose interferon-alpha2b treatment prevents chronicity in acute hepatitis C: a pilot study Dig Dis Sci 41 1996 81S 85S
72. M. Omata, O. Yokosuka, S. Takano, N. Kato, K. Hosoda, and F. Imazeki Resolution of acute hepatitis C after therapy with natural beta interferon Lancet 338 1991 914 915
73. S.J. Hwang, S.D. Lee, C.Y. Chan, R.H. Lu, and K.J. Lo A randomized controlled trial of recombinant interferon alpha-2b in the treatment of Chinese patients with acute post-transfusion hepatitis C J Hepatol 21 1994 831 836
74. S. Takano, Y. Satomura, and M. Omata Effects of interferon beta on non-A, non-B acute hepatitis: a prospective, randomized, controlled-dose study. Japan Acute Hepatitis Cooperative Study Group Gastroenterology 107 1994 805 811
75. P. Lampertico, M. Rumi, R. Romeo, A. Craxì, R. Soffredini, and D. Biassoni A multicenter randomized controlled trial of recombinant interferon alpha-2b in patients with acute transfusion-associated hepatitis C Hepatology 19 1994 19 22
76. P. Fabris, G. Tositti, M.T. Giordani, D. Infantolino, and F. deLalla Three times weekly versus daily dose alpha-interferon treatment in patients with acute hepatitis C Am J Gastroenterol 97 2002 492 493
77. G. Calleri, P. Colombatto, M. Gozzelino, F. Chieppa, P. Romano, and B. Delmastro Natural beta interferon in acute type-C hepatitis patients: a randomized controlled trial Ital J Gastroenterol Hepatol 30 1998 181 184
78. M. Gursoy, G. Gur, H. Arslan, N. Ozdemir, and S. Boyacioglu Interferon therapy in haemodialysis patients with acute hepatitis C virus infection and factors that predict response to treatment J Viral Hepatol 8 2001 70 77
79. A. Licata, D. Di Bona, F. Schepis, L. Shahied, A. Craxi, and C. Camma When and how to treat acute hepatitis C? J Hepatol 39 2003 1056 1062
80. H. Nomura, S. Sou, H. Tanimoto, T. Nagahama, Y. Kimura, and J. Hayashi Short-term interferon-alfa therapy for acute hepatitis C: a randomized controlled trial Hepatology 39 2004 1213 1219
81. T. Santantonio, M. Fasano, E. Sinisi, A. Guastadisegni, C. Casalino, and M. Mazzola Efficacy of a 24-week course of PEG-interferon α-2b monotherapy in patients with acute hepatitis C after failure of spontaneous clearance J Hepatol 42 2005 329 333