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Volumn 17, Issue 2, 2005, Pages 145-147

Antibiotics for inflammatory bowel disease: Do they work?

Author keywords

Ciprofloxacin; Crohn's disease; Metronidazole; Pouchitis; Rifaximin; Ulcerative colitis

Indexed keywords

AZATHIOPRINE; BUDESONIDE; CIPROFLOXACIN; CORTICOSTEROID; COTRIMOXAZOLE; IMMUNOSUPPRESSIVE AGENT; MESALAZINE; METHYLPREDNISOLONE; METRONIDAZOLE; PLACEBO; RIFAXIMIN; SALAZOSULFAPYRIDINE; TOBRAMYCIN; TUBERCULOSTATIC AGENT; VANCOMYCIN;

EID: 14844323120     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042737-200502000-00003     Document Type: Review
Times cited : (49)

References (48)
  • 1
    • 0031012926 scopus 로고    scopus 로고
    • T-cell receptor-alpha-beta-deficient mice fail to develop colitis in the absence of a microbial environment
    • Dianda L, Hanby AM, Wright NA, Sebesteny A, Hayday AC, Owen MJ. T-cell receptor-alpha-beta-deficient mice fail to develop colitis in the absence of a microbial environment. Am J Pathol 1997; 150:91-97.
    • (1997) Am J Pathol , vol.150 , pp. 91-97
    • Dianda, L.1    Hanby, A.M.2    Wright, N.A.3    Sebesteny, A.4    Hayday, A.C.5    Owen, M.J.6
  • 3
    • 0031915148 scopus 로고    scopus 로고
    • Early lesions of recurrent Crohn's disease caused by infusion of intestinal content in excluded ileum
    • D'Haens GR, Geboes K, Peeters M, Baert F, Penninckx F, Rutgeerts P. Early lesions of recurrent Crohn's disease caused by infusion of intestinal content in excluded ileum. Gastroenterology 1998; 114:262-267.
    • (1998) Gastroenterology , vol.114 , pp. 262-267
    • D'Haens, G.R.1    Geboes, K.2    Peeters, M.3    Baert, F.4    Penninckx, F.5    Rutgeerts, P.6
  • 5
    • 0029586031 scopus 로고
    • Tolerance exists towards resident intestinal flora in mice but is broken in active inflammatory bowel disease
    • Duchmann R, Schmitt E, Knoll P. Tolerance exists towards resident intestinal flora in mice but is broken in active inflammatory bowel disease. Clin Exp Immunol 1995; 102:448-455.
    • (1995) Clin Exp Immunol , vol.102 , pp. 448-455
    • Duchmann, R.1    Schmitt, E.2    Knoll, P.3
  • 6
    • 0026597788 scopus 로고
    • Virulence properties of Escherichia coli isolated from patients with inflammatory bowel disease
    • Giaffer MH, Holdsworth CD, Duerden BI. Virulence properties of Escherichia coli isolated from patients with inflammatory bowel disease. Gut 1992; 33:646-650.
    • (1992) Gut , vol.33 , pp. 646-650
    • Giaffer, M.H.1    Holdsworth, C.D.2    Duerden, B.I.3
  • 7
    • 0037302961 scopus 로고    scopus 로고
    • Alterations of the dominant faecal bacterial groups in patients with Crohn's disease of the colon
    • Selsik P, Rigottier-Gois L, Gramet G, Sutren M, Pochart P, Marteau P, et al. Alterations of the dominant faecal bacterial groups in patients with Crohn's disease of the colon. Gut 2002; 52:237-242.
    • (2002) Gut , vol.52 , pp. 237-242
    • Selsik, P.1    Rigottier-Gois, L.2    Gramet, G.3    Sutren, M.4    Pochart, P.5    Marteau, P.6
  • 8
    • 0021709791 scopus 로고
    • Possible role of mycobacteria in inflammatory bowel disease. An unclassified mycobacterium species isolated from patients with Crohn's disease
    • Chiodini RJ, van Kruiningen HJ, Thayer WR Jr, Merkal RS, Coutu JA. Possible role of mycobacteria in inflammatory bowel disease. An unclassified mycobacterium species isolated from patients with Crohn's disease. Dig Dis Sci 1984; 29:1073-1079.
    • (1984) Dig Dis Sci , vol.29 , pp. 1073-1079
    • Chiodini, R.J.1    Van Kruiningen, H.J.2    Thayer Jr., W.R.3    Merkal, R.S.4    Coutu, J.A.5
  • 9
    • 0006525266 scopus 로고
    • Infective agents-mycobacteria
    • Kirsner JB, Shorter RG (editors): Baltimore: Williams & Wilkins
    • Fidler HM, Mc Fadden A. Infective agents-mycobacteria. In: Kirsner JB, Shorter RG (editors): Inflammatory Bowel Disease, 4th edition, Baltimore: Williams & Wilkins; 1995, pp. 125-131.
    • (1995) Inflammatory Bowel Disease, 4th Edition , pp. 125-131
    • Fidler, H.M.1    Mc Fadden, A.2
  • 10
    • 0027427419 scopus 로고
    • Impairment of bacterial flora in human ulcerative colitis and experimental colitis in rats
    • Fabia R, Ar'Rajab A, Joahnsson ML, Andersson R, Willen R, Jeppson B. Impairment of bacterial flora in human ulcerative colitis and experimental colitis in rats. Digestion 1993; 54:248-255.
    • (1993) Digestion , vol.54 , pp. 248-255
    • Fabia, R.1    Ar'Rajab, A.2    Joahnsson, M.L.3    Andersson, R.4    Willen, R.5    Jeppson, B.6
  • 13
    • 0021208056 scopus 로고
    • Patients with active Crohn's disease have elevated serum antibodies to antigens of seven enteric bacterial pathogens
    • Blaser MJ, Miller RA, Lacher J, Singleton JW. Patients with active Crohn's disease have elevated serum antibodies to antigens of seven enteric bacterial pathogens. Gastroenterology 1984; 87:888-891.
    • (1984) Gastroenterology , vol.87 , pp. 888-891
    • Blaser, M.J.1    Miller, R.A.2    Lacher, J.3    Singleton, J.W.4
  • 15
    • 0017732425 scopus 로고
    • Metronidazole in the treatment of chronic proctitis. A controlled study
    • Davies PS, Rhodes J, Heatley RV, Owen E. Metronidazole in the treatment of chronic proctitis. A controlled study. Gut 1987; 18:680-681.
    • (1987) Gut , vol.18 , pp. 680-681
    • Davies, P.S.1    Rhodes, J.2    Heatley, R.V.3    Owen, E.4
  • 16
    • 0023234541 scopus 로고
    • A comparative study of metronidazole and sulfasalazine in active, non severe ulcerative colitis
    • Gilat T, Suissa A, Leitchman G, Delpre G, Pavlotzky M, Grossman A, et al. A comparative study of metronidazole and sulfasalazine in active, non severe ulcerative colitis. J Clin Gastroenterol 1987; 9:415-417.
    • (1987) J Clin Gastroenterol , vol.9 , pp. 415-417
    • Gilat, T.1    Suissa, A.2    Leitchman, G.3    Delpre, G.4    Pavlotzky, M.5    Grossman, A.6
  • 17
    • 0022505628 scopus 로고
    • Controlled trial of intravenous metronidazole as an adjunct to corticosteroids in severe ulcerative colitis
    • Chapman RW, Selby WS, Jewel DP. Controlled trial of intravenous metronidazole as an adjunct to corticosteroids in severe ulcerative colitis. Gut 1986; 27:1210-1212.
    • (1986) Gut , vol.27 , pp. 1210-1212
    • Chapman, R.W.1    Selby, W.S.2    Jewel, D.P.3
  • 18
    • 0028286347 scopus 로고
    • Double-blind crossover trial of metronidazole versus placebo in chronic unremitting pouchitis
    • Madden MV, McIntyre AS, Nicholls RJ. Double-blind crossover trial of metronidazole versus placebo in chronic unremitting pouchitis. Dig Dis Sci 1994; 39:1193-1196.
    • (1994) Dig Dis Sci , vol.39 , pp. 1193-1196
    • Madden, M.V.1    McIntyre, A.S.2    Nicholls, R.J.3
  • 20
    • 0036242734 scopus 로고    scopus 로고
    • Four-week open-label trial of metronidazole and ciprofloxacin for the treatment of recurrent or refractory pouchitis
    • Mimura T, Rizzello F, Helwig U, Poggioli G, Schreiber C, Talbot IC, et al. Four-week open-label trial of metronidazole and ciprofloxacin for the treatment of recurrent or refractory pouchitis. Aliment Pharmacol Ther 2002; 16:909-917.
    • (2002) Aliment Pharmacol Ther , vol.16 , pp. 909-917
    • Mimura, T.1    Rizzello, F.2    Helwig, U.3    Poggioli, G.4    Schreiber, C.5    Talbot, I.C.6
  • 22
    • 0025887808 scopus 로고
    • Double-blind placebo-controlled trial of metronidazole in Crohn's disease
    • Sutherland L, Singleton J, Sessions J, Hanauer S, Krawitt E, Rankin G, et al. Double-blind placebo-controlled trial of metronidazole in Crohn's disease. Gut 1991; 32:1071-1075.
    • (1991) Gut , vol.32 , pp. 1071-1075
    • Sutherland, L.1    Singleton, J.2    Sessions, J.3    Hanauer, S.4    Krawitt, E.5    Rankin, G.6
  • 23
    • 0022001215 scopus 로고
    • Antibiotic therapy for treatment in relapse of intestinal Crohn's disease. A prospective randomized study
    • Ambrose NS, Allan RN, Keighley MR, Burd DW, Youngs D, Barnes P, et al. Antibiotic therapy for treatment in relapse of intestinal Crohn's disease. A prospective randomized study. Dis Colon Rectum 1985; 28:81-85.
    • (1985) Dis Colon Rectum , vol.28 , pp. 81-85
    • Ambrose, N.S.1    Allan, R.N.2    Keighley, M.R.3    Burd, D.W.4    Youngs, D.5    Barnes, P.6
  • 24
    • 0019958789 scopus 로고
    • A comparative study of metronidazole and sulfasalazine for active Crohn's disease: The cooperative Crohn's disease study in Sweden
    • Rosen A, Ursing B, Alm T, Barani F, Bergelin I, Ganrot-Norlin K, et al. A comparative study of metronidazole and sulfasalazine for active Crohn's disease: the cooperative Crohn's disease study in Sweden. Gastroenterology 1982; 83:550-562.
    • (1982) Gastroenterology , vol.83 , pp. 550-562
    • Rosen, A.1    Ursing, B.2    Alm, T.3    Barani, F.4    Bergelin, I.5    Ganrot-Norlin, K.6
  • 25
    • 0030065270 scopus 로고    scopus 로고
    • An antibiotic regimen for the treatment of active Crohn's disease: A randomized, controlled trial of metronidazole plus ciprofloxacin
    • Prantera C, Zannoni F, Scribano ML, Falarco G. An antibiotic regimen for the treatment of active Crohn's disease: a randomized, controlled trial of metronidazole plus ciprofloxacin. Am J Gastroenterol 1996; 91: 328-332.
    • (1996) Am J Gastroenterol , vol.91 , pp. 328-332
    • Prantera, C.1    Zannoni, F.2    Scribano, M.L.3    Falarco, G.4
  • 26
    • 0029079279 scopus 로고
    • Controlled trial of metronidazole treatment for prevention of Crohn's recurrence after ileal resection
    • Rutgeerts P, Hiele M, Geboes K, Peeters M, Pennickx F, Aerts R, et al. Controlled trial of metronidazole treatment for prevention of Crohn's recurrence after ileal resection. Gastroenterology 1995; 108:1617-1621.
    • (1995) Gastroenterology , vol.108 , pp. 1617-1621
    • Rutgeerts, P.1    Hiele, M.2    Geboes, K.3    Peeters, M.4    Pennickx, F.5    Aerts, R.6
  • 28
    • 0019977612 scopus 로고
    • Metronidazole therapy for perineal Crohn's disease: A follow-up study
    • Brandt U, Bernstein LH, Boley SJ, Franks MS. Metronidazole therapy for perineal Crohn's disease: a follow-up study. Gastroenterology 1982; 83:33-37.
    • (1982) Gastroenterology , vol.83 , pp. 33-37
    • Brandt, U.1    Bernstein, L.H.2    Boley, S.J.3    Franks, M.S.4
  • 29
    • 0021264732 scopus 로고
    • Metronidazole therapy for Crohn's disease and associated fistulae
    • Jakobivtzs J, Schuster MM. Metronidazole therapy for Crohn's disease and associated fistulae. Am J Gastroenterol 1984; 79:533-540.
    • (1984) Am J Gastroenterol , vol.79 , pp. 533-540
    • Jakobivtzs, J.1    Schuster, M.M.2
  • 30
    • 0030068415 scopus 로고    scopus 로고
    • Perianal Crohn's disease: Is it all bad news?
    • McKee RF, Keenan RA. Perianal Crohn's disease: is it all bad news? Dis Colon Rectum 1996; 39:136-142.
    • (1996) Dis Colon Rectum , vol.39 , pp. 136-142
    • McKee, R.F.1    Keenan, R.A.2
  • 32
    • 0031763109 scopus 로고    scopus 로고
    • Long-term treatment of ulcerative colitis with ciprofloxacin: A prospective double-blind, placebo-controlled study
    • Turunen UM, Farkkila MA, Hakala K, Seppala K, Sivonen A, Ogren M, et al. Long-term treatment of ulcerative colitis with ciprofloxacin: a prospective double-blind, placebo-controlled study. Gastroenterology 1998; 115: 1072-1078.
    • (1998) Gastroenterology , vol.115 , pp. 1072-1078
    • Turunen, U.M.1    Farkkila, M.A.2    Hakala, K.3    Seppala, K.4    Sivonen, A.5    Ogren, M.6
  • 33
    • 0034912789 scopus 로고    scopus 로고
    • A prospective randomized controlled trial of intravenous ciprofloxacin as an adjunct to corticosteroids in acute, severe ulcerative colitis
    • Mantzaris GJ, Petraki K, Archavlis E, Amberiadis P, Kourtessas D, Christidou A, et al. A prospective randomized controlled trial of intravenous ciprofloxacin as an adjunct to corticosteroids in acute, severe ulcerative colitis. Scand J Gastroenterol 2001; 36:971-974.
    • (2001) Scand J Gastroenterol , vol.36 , pp. 971-974
    • Mantzaris, G.J.1    Petraki, K.2    Archavlis, E.3    Amberiadis, P.4    Kourtessas, D.5    Christidou, A.6
  • 34
    • 0029918932 scopus 로고    scopus 로고
    • Prospective study of the incidence, timing and treatment of pouchitis in 104 consecutive patients after restorative proctocolectomy
    • Hurst RD, Molinari M, Chung TP. Prospective study of the incidence, timing and treatment of pouchitis in 104 consecutive patients after restorative proctocolectomy. Arch Surg 1996; 131:497-500.
    • (1996) Arch Surg , vol.131 , pp. 497-500
    • Hurst, R.D.1    Molinari, M.2    Chung, T.P.3
  • 35
    • 0027520524 scopus 로고
    • Combination ciprofloxacin and metronidazole in severe perianal Crohn's disease
    • Solomon MJ, McLeod RS, O'Connor BL. Combination ciprofloxacin and metronidazole in severe perianal Crohn's disease. Can J Gastroenterol 1993; 7:571-572.
    • (1993) Can J Gastroenterol , vol.7 , pp. 571-572
    • Solomon, M.J.1    McLeod, R.S.2    O'Connor, B.L.3
  • 36
    • 0031905237 scopus 로고    scopus 로고
    • Combination ciprofloxacin and metronidazole for active Crohn's disease
    • Greenbloom SL, Steinhart AH, Greenberg GR. Combination ciprofloxacin and metronidazole for active Crohn's disease. Can J Gastroenterol 1998; 12:53-56.
    • (1998) Can J Gastroenterol , vol.12 , pp. 53-56
    • Greenbloom, S.L.1    Steinhart, A.H.2    Greenberg, G.R.3
  • 38
    • 0344457371 scopus 로고    scopus 로고
    • A controlled trial comparing ciprofloxacin with mesalazine for the treatment of active Crohn's disease
    • Colombel JF, Lemann M, Cassagnou M, Bouknik Y, Duclos B, Dupas JL, et al. A controlled trial comparing ciprofloxacin with mesalazine for the treatment of active Crohn's disease. Am J Gastroenterol 1999; 94:674-678.
    • (1999) Am J Gastroenterol , vol.94 , pp. 674-678
    • Colombel, J.F.1    Lemann, M.2    Cassagnou, M.3    Bouknik, Y.4    Duclos, B.5    Dupas, J.L.6
  • 39
    • 0032458052 scopus 로고    scopus 로고
    • Use of antibiotics in the treatment of active Crohn's disease: Experience with metronidazole and ciprofloxacin
    • Prantera C, Berto E, Scribano ML, Falasco G. Use of antibiotics in the treatment of active Crohn's disease: experience with metronidazole and ciprofloxacin. Ital J Gastroenterol Hepatol 1998; 30:602-606.
    • (1998) Ital J Gastroenterol Hepatol , vol.30 , pp. 602-606
    • Prantera, C.1    Berto, E.2    Scribano, M.L.3    Falasco, G.4
  • 41
    • 0034068566 scopus 로고    scopus 로고
    • Antibacterial therapy for Crohn's disease: A review emphasizing therapy directed against mycobacteria
    • Hulten K, Almashhrawi A, El-Zaatari F, Graham DY. Antibacterial therapy for Crohn's disease: a review emphasizing therapy directed against mycobacteria. Dig Dis Sci 2000; 45:445-446.
    • (2000) Dig Dis Sci , vol.45 , pp. 445-446
    • Hulten, K.1    Almashhrawi, A.2    El-Zaatari, F.3    Graham, D.Y.4
  • 42
    • 0022392051 scopus 로고
    • Double blind controlled trial of oral vancomycin as adjunctive treatment in acute exacerbations of idiopathic colitis
    • Dickinson RJ, O'Connor HJ, Pinder I. Double blind controlled trial of oral vancomycin as adjunctive treatment in acute exacerbations of idiopathic colitis. Gut 1985; 26:1380-1384.
    • (1985) Gut , vol.26 , pp. 1380-1384
    • Dickinson, R.J.1    O'Connor, H.J.2    Pinder, I.3
  • 44
    • 0033059934 scopus 로고    scopus 로고
    • Rifaximin in patients with moderate or severe ulcerative colitis refractory to steroid treatment: A double-blind placebo-controlled trial
    • Gionchetti P, Rizzello F, Ferrieri A, Venturi A, Brignola C, Ferretti M, et al. Rifaximin in patients with moderate or severe ulcerative colitis refractory to steroid treatment: a double-blind placebo-controlled trial. Dig Dis Sci 1999; 44:1220-1221.
    • (1999) Dig Dis Sci , vol.44 , pp. 1220-1221
    • Gionchetti, P.1    Rizzello, F.2    Ferrieri, A.3    Venturi, A.4    Brignola, C.5    Ferretti, M.6
  • 45
    • 5444232421 scopus 로고    scopus 로고
    • Corticosteroid-sparing effect of rifaximin, a nonabsorbable oral antibiotic, in active ulcerative colitis: Preliminary clinical experience
    • Gusland M, Giollo P, Testoni PA. Corticosteroid-sparing effect of rifaximin, a nonabsorbable oral antibiotic, in active ulcerative colitis: preliminary clinical experience. Curr Ther Res Clin Exp 2004; 65:292-296.
    • (2004) Curr Ther Res Clin Exp , vol.65 , pp. 292-296
    • Gusland, M.1    Giollo, P.2    Testoni, P.A.3
  • 46
    • 2442579438 scopus 로고    scopus 로고
    • Efficacy and tolerability of rifaximin, a nonabsorbed oral antibiotic, in the treatment of active Crohn's disease: Results of an open-label study
    • Shafran I, Johnson LK, Hamm L, Murdocj RH. Efficacy and tolerability of rifaximin, a nonabsorbed oral antibiotic, in the treatment of active Crohn's disease: results of an open-label study. Am J Gastroenterol 2003; 98 (suppl):S250.
    • (2003) Am J Gastroenterol , vol.98 , Issue.SUPPL.
    • Shafran, I.1    Johnson, L.K.2    Hamm, L.3    Murdocj, R.H.4
  • 48
    • 0344665570 scopus 로고    scopus 로고
    • Antibiotics with a selective aerobic or anaerobic spectrum have different therapeutic activities in various regions of the colon in interleukin 10 gene deficient mice
    • Hoentjen F, Harmsen HJM, Braat H, Torrice CD, Mann BA, Sartor RB, et al. Antibiotics with a selective aerobic or anaerobic spectrum have different therapeutic activities in various regions of the colon in interleukin 10 gene deficient mice. Gut 2003; 52:1721-1727.
    • (2003) Gut , vol.52 , pp. 1721-1727
    • Hoentjen, F.1    Harmsen, H.J.M.2    Braat, H.3    Torrice, C.D.4    Mann, B.A.5    Sartor, R.B.6


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