In vitro characterization of novel NR2B selective NMDA receptor antagonists

Neurochemistry International

Volumn 46, Issue 6, 2005, Pages 453-464

  Kiss, Laszlo ^a   Cheng, Gong ^a   Bednar, Bohumil ^a   Bednar, Rodney A ^a   Bennett, Paul B ^a   Kane, Stefanie A ^a   McIntyre, Charles J ^a   McCauley, John A ^a   Koblan, Kenneth S ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Ifenprodil; Kinetics; Maximal inhibition; MERCK 1; MERCK 2; MERCK 3; N Methyl d aspartate (NMDA); NMDA receptors; Subtype selectivity

Indexed keywords

4 [1 HYDROXY 2 [[[4 (4 METHOXYPHENYL) 1,3 THIAZOL 2 YL]METHYL]AMINO]PROPYL] PHENOL; CALCIUM; IFENPRODIL; N 1 (2 METHOXYBENZYL)CINNAMAMIDINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; N [2 [(4 BENZYLPIPERIDIN 1 YL)METHYL]BENZIMIDAZOL 5 YL]METHANESULFONAMIDE; RADIOLIGAND; RECEPTOR SUBTYPE; RECOMBINANT RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CELL LINE; CELL SPECIFICITY; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG INHIBITION; DRUG MECHANISM; DRUG RECEPTOR BINDING; ELECTRIC POTENTIAL; ELECTROPHYSIOLOGY; LIGAND BINDING; MOUSE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR AFFINITY; WHOLE CELL;

EID: 14844320067     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2004.12.008     Document Type: Article

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