Synthesis of NE-(7-diethylaminocoumarin-3-carboxyl)- and NE-(7-methoxycoumarin-3-carboxyl)-L-Fmoc lysine as tools for protease cleavage detection by fluorescence

Journal of Peptide Science

Volumn 11, Issue 3, 2005, Pages 153-160

  Berthelot, Thomas ^a   Talbot, Jean Claude ^b   Laïn, Georges ^a   Déleris, Gérard ^a   Latxague, Laurent ^a  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b Institut de Biochimie et Genetique Cellulaires   (France)

Author keywords

Coumarins; Fluorescent amino acids; Fluorogenic substrates; Matrix metalloprotease activity

Indexed keywords

AMINO ACID; CARBOXYLIC ACID DERIVATIVE; COUMARIN DERIVATIVE; INTERSTITIAL COLLAGENASE; LYSINE DERIVATIVE; PEPTIDE; PROTEINASE; SUCCINIMIDE DERIVATIVE; DRUG DERIVATIVE; LYSINE; N(EPSILON) (7 DIETHYLAMINOCOUMARIN 3 CARBOXYL) 9 FLUORENYLMETHOXYCARBONYLLYSINE; N(EPSILON) (7 METHOXYCOUMARIN 3 CARBOXYL) 9 FLUORENYLMETHOXYCARBONYLLYSINE; N(EPSILON)-(7-DIETHYLAMINOCOUMARIN-3-CARBOXYL)-9-FLUORENYLMETHOXYCARBONYLLYSINE; N(EPSILON)-(7-METHOXYCOUMARIN-3-CARBOXYL)-9-FLUORENYLMETHOXYCARBONYLLYSINE;

ARTICLE; CHEMICAL LABELING; CHEMICAL PROCEDURES; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEGRADATION; FLUORESCENCE RESONANCE ENERGY TRANSFER; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; SOLID PHASE SYNTHESIS; SYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KINETICS; METABOLISM;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COUMARINS; FLUORESCENCE; FLUORESCENCE RESONANCE ENERGY TRANSFER; KINETICS; LYSINE; MATRIX METALLOPROTEINASE 1; MOLECULAR STRUCTURE;

EID: 14844317320     PISSN: 10752617     EISSN: None     Source Type: Journal    
DOI: 10.1002/psc.608     Document Type: Article

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