Low immunogenicity of in vitro-expanded human neural cells despite high MHC expression

Journal of Neuroimmunology

Volumn 161, Issue 1-2, 2005, Pages 1-11

  Odeberg, Jenny ^a,b   Piao, Jing Hua ^a   Samuelsson, Eva Britt ^a   Falci, Scott ^c   Åkesson, Elisabet ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b Stockholms Sjukhem Foundation   (Sweden)

^c CRAIG HOSPITAL   (United States)

Author keywords

Co stimulatory molecules; Forebrain; Human; MHC; Neurosphere; Spinal cord

Indexed keywords

B7 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2;

ANTIGEN EXPRESSION; ARTICLE; COCULTURE; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOGENICITY; MAJOR HISTOCOMPATIBILITY COMPLEX; NERVE CELL; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL;

EID: 14844304696     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2004.11.016     Document Type: Article

References (31)

1. N. Abdel-Haq, H.-N. Hao, and W.D. Lyman Cytokine regulation of CD40 expression in fetal human astrocyte cultures J. Neuroimmunol. 101 1999 7 14
2. E. Åkesson, L. Markling, A. Kjaeldgaard, S. Falci, and O. Ringdén MHC antigen expression in human first trimester spinal cord with implications for clinical transplantation procedures J. Neuroimmunol. 111 1-2 2000 210 214
3. Åkesson, E., Piao J.-H., Samuelsson, E.-B., Holmberg, L., Kjaeldgaard, A., Falci, S., Sundström, E., Seiger, Å., in press. Long-term culture and neuronal survival after intraspinal transplantation of human spinal cord-derived neurospheres. Physiol. Behav.
4. Y. Akiyama, O. Honmou, T. Kato, T. Uede, K. Hashi, and J.D. Kocsis Transplantation of clonal neural precursor cells derived from adult human brain establishes functional peripheral myelin in the rat spinal cord Exp. Neurol. 167 2001 27 39
5. S. Bixby, G.M. Kruger, J.T. Mosher, N.M. Joseph, and S.J. Morrison Cell-intrinsic differences between stem cells from different regions of the peripheral nervous system regulate the generation of neural diversity Neuron 35 2002 643 656
6. L.M. Boulanger, G.S. Huh, and C.J. Shatz Neuronal plasticity and cellular immunity: shared molecular mechanisms Curr. Opin. Neurobiol. 11 5 2001 568 578
7. M.K. Carpenter, X. Cui, Z.-Y. Hu, J. Jackson, S. Sherman, Å. Seiger, and L.U. Wahlberg In vitro expansion of a multipotent population of human neural progenitor cells Exp. Neurol. 158 1999 265 278
8. Y. Dong, and E.N. Benveniste Immune function of astrocytes Glia 36 2001 180 190
9. M. Drukker, G. Katz, A. Urbach, M. Schuldiner, G. Markel, J. Itskovitz-Eldor, B. Reubinoff, O. Mandelboim, and N. Benvenisty Characterization of the expression of MHC proteins in human embryonic stem cells PNAS 99 15 2002 9864 9869
10. W.-M. Duan, H. Widner, and P. Brundin Temporal pattern of host responses against intrastriatal grafts of syngeneic, allogeneic or xenogeneic embryonic neuronal tissue in rats Exp. Brain Res. 104 1995 227 242
11. W.-M. Duan, H. Widner, E.M. Frodl, and P. Brundin Immune reactions following systemic immunization prior or subsequent to intrastriatal transplantation of allogeneic mesencephalic tissue in adult rats Neuroscience 64 1995 629 641
12. W.-M. Duan, H. Widner, E.M. Frodl, and P. Brundin Addition of allogeneic spleen cells causes rejection of intrastriatal embryonic mesencephalic allografts in the rat Neuroscience 77 2 1997 599 609
13. M.A. England A colour atlas of life before birth 1990 Hazell books Aylesbury, Bucks, England
14. R.A. Fricker, M.K. Carpenter, C. Winkler, C. Greco, M.A. Gates, and A. Björklund Site-specific migration and neuronal differentiation of human neural progenitor cells after transplantation in the adult rat brain J. Neurosci. 19 14 1999 5990 6005
15. C. Geny, S. Naimi-Sadaoui, A.E. Belkadi, R. Jeny, M. Kammoun, and M. Peschanski Microglial chimaerism in human xenografts to the rat brain Brain Res. Bull. 38 4 1995 383 391
16. Y. Grenier, T.C. Rujis, Y. Robitaille, A. Olivier, and J.P. Antel Immunohistochemical studies of adult human glial cells J. Neuroimmunol. 21 2-3 1989 103 115
17. G.S. Huh, L.M. Boulanger, H. Du, P.A. Riquelme, T.M. Brotz, and C.J. Shatz Functional requirement for class I MHC in CNS development and plasticity Science 290 2000 2155 2159
18. J. Imitola, M. Comabella, A.K. Chandraker, F. Dangond, M.H. Savegh, E.Y. Snyder, and S.J. Khoury Am. J. Pathol. 164 2004 1615 1625
19. K. Le Blanc, C. Tammik, K. Rosendahl, K. Zetterberg, and O. Ringdén HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells Exp. Hematol. 31 2003 890 896
20. G. Lombardi, S. Sidhu, R. Batchelor, and R. Lechler Anergic T cells as suppressor cells in vitro Science 266 5184 1994 464 465
21. P.T. Massa, E.P. Cowan, B.Z. Levi, K. Ozato, and D.E. McFarlin Genetic regulation of class I major histocompatibility complex (MHC) antigen induction on astrocytes J. Neuroimmunol. 24 1-2 1989 125 132
22. F.H. McLaren, C.N. Svendsen, P. Van der Meide, and E. Joly Analysis of neural stem cells by flow cytometry: cellular differentiation modifies patterns of MHC expression J. Neuroimmunol. 112 2001 35 46
23. M. Modo, K. Mellodew, and P. Rezaie In vitro expression of major histocompatibility class I and class II antigens by conditionally immortalized murine neural stem cells Neurosci. Lett. 337 2003 85 88
24. J. New, S. Chan, E. Yap, and H. Hu Induction of acute graft-versus-host disease by T cells that do not respond to in vitro alloantigen stimulation Br. J. Haematol. 126 2004 828 836
25. P. Rezaie, and D. Male Colonisation of the developing human brain and spinal cord by microglia: a review Microsc. Res. Tech. 45 6 1999 359 382
26. P. Rezaie, K. Patel, and D.K. Male Microglia in the human fetal spinal cord: patterns of distribution, morphology and phenotype Brain Res. Dev. Brain Res. 115 1 1999 71 81
27. J.-H. Satoh, Y.B. Lee, and S.U. Kim T-cell co-stimulatory molecules B7-1 (CD80) and B7-2 (CD86) are expressed in human microglia but not in astrocytes in culture Brain Res. 704 1995 92 96
28. R.H. Schwartz A cell culture model for T lymphocyte clonal anergy Science 248 1990 1349 1356
29. H. Song, C.F. Stevens, and F.H. Gage Astroglia induce neurogenesis from adult neural stem cells Nature 417 2002 39 44
30. W.T. Tse, J.D. Pendleton, W.M. Beyer, M.C. Egalka, and E.C. Guinan Suppression of allogeneic T-cell proliferation by human marrow stromal cells: implications in transplantation Transplantation 75 3 2003 389 397
31. L.A. White, R.W. Keane, and S.R. Whittemore Differentiation of an immortalized CNS neuronal cell line decreases their susceptibility to cytotoxic T cell lysis in vitro J. Neuroimmunol. 49 1-2 1994 135 143