Human xylosyltransferase I: Functional and biochemical characterization of cysteine residues required for enzymic activity

Biochemical Journal

Volumn 386, Issue 2, 2005, Pages 227-236

  Müller, Sandra ^a   Schöttler, Manuela ^a   Schön, Sylvia ^a   Prante, Christian ^a   Brinkmann, Thomas ^a   Kuhn, Joachim ^a   Götting, Christian ^a   Kleesiek, Knut ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Cysteine; Functional characterization; Glycosaminoglycan; Proteoglycan; Site directed mutagenesis; Xylosyltransferase I

Indexed keywords

BINDING ENERGY; BIOSYNTHESIS; CATALYSIS; CELLS; DIMERS; ELECTROPHORESIS; MUTAGENESIS;

GLYCOSAMINOGLYCANS; MOLECULAR MASSES; PROTEOGLYCANS; XYLOSYLTRANSFERASE I (XT-I);

ENZYMES;

HEPARIN; MALEIMIDE DERIVATIVE; N PHENYLMALEIMIDE; TRANSFERASE; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE; XYLOSYLTRANSFERASE I;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CATALYSIS; DISULFIDE BOND; ENZYME ACTIVITY; ENZYME INACTIVATION; GENE EXPRESSION SYSTEM; INSECT CELL; MICHAELIS CONSTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; CATALYSIS; CELL LINE; CHONDROITIN SULFATES; CLONING, MOLECULAR; CYSTEINE; DISULFIDES; DITHIOTHREITOL; ENZYME INHIBITORS; EPITOPES; HEPARIN; HEPARITIN SULFATE; HUMANS; INSECTS; MALEIMIDES; MICROSPHERES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; OXIDATION-REDUCTION; PENTOSYLTRANSFERASES; RECOMBINANT PROTEINS; SOLUBILITY; URIDINE DIPHOSPHATE;

INSECTA;

EID: 14844298775     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20041206     Document Type: Article

References (38)

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