Location and mechanism of α2,6-sialyltransferase dimer formation. Role of cysteine residues in enzyme dimerization, localization, activity, and processing

Journal of Biological Chemistry

Volumn 276, Issue 31, 2001, Pages 28641-28649

  Qian, Rong ^b   Chen, Chun ^b   Colley, Karen J ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSYLATION;

AMINO ACIDS; CATALYSIS; CHEMICAL BONDS; DIMERIZATION; DIMERS; ENZYMES; MUTAGENESIS;

BIOCHEMISTRY;

ALPHA 2,6 SIALYLTRANSFERASE; AMINO ACID; ASIALOGLYCOPROTEIN; CYSTEINE; DIMER; ENZYME; PROTEIN; SIALYLTRANSFERASE; ST6GAL I ENZYME; UNCLASSIFIED DRUG; ASPARAGINE; BETA D GALACTOSIDE ALPHA 2 6 SIALYLTRANSFERASE; BETA-D-GALACTOSIDE ALPHA 2-6-SIALYLTRANSFERASE; CYSTINE; CYTIDINE PHOSPHATE N ACETYLNEURAMINIC ACID; DISULFIDE; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; CATALYSIS; CELLULAR DISTRIBUTION; DIMERIZATION; DISULFIDE BOND; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME LOCALIZATION; GLYCOSYLATION; GOLGI COMPLEX; MUTAGENESIS; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; AFFINITY CHROMATOGRAPHY; AMINO ACID SUBSTITUTION; ANIMAL; CELL STRAIN COS1; CERCOPITHECUS; CHEMISTRY; CHO CELL; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; HAMSTER; ISOLATION AND PURIFICATION; KINETICS; METABOLISM; PROTEIN TRANSPORT; SITE DIRECTED MUTAGENESIS;

ANIMALIA;

AMINO ACID SUBSTITUTION; ANIMALS; ASPARAGINE; CATALYSIS; CERCOPITHECUS AETHIOPS; CHO CELLS; CHROMATOGRAPHY, AFFINITY; COS CELLS; CRICETINAE; CYSTINE; CYTIDINE MONOPHOSPHATE N-ACETYLNEURAMINIC ACID; DIMERIZATION; DISULFIDES; ENDOPLASMIC RETICULUM; GOLGI APPARATUS; KINETICS; MUTAGENESIS, SITE-DIRECTED; PROTEIN TRANSPORT; RECOMBINANT PROTEINS; SIALYLTRANSFERASES; TRANSFECTION;

EID: 0035800822     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M103664200     Document Type: Article

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