메뉴 건너뛰기




Volumn 12, Issue 2, 2005, Pages 146-153

Hot-spot mutations in hepatitis B virus core gene: Eliciting or evading immune clearance?

Author keywords

Hepatitis B virus; Immune response; Mutation; Recombinant adenovirus

Indexed keywords

ADENOVIRUS VECTOR; HEPATITIS B CORE ANTIGEN; HEPATITIS B SURFACE ANTIGEN; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; THYMIDINE; TRITIUM; VIRUS DNA;

EID: 14844292589     PISSN: 13520504     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2893.2005.00552.x     Document Type: Article
Times cited : (23)

References (32)
  • 1
    • 0037283535 scopus 로고    scopus 로고
    • Hepatitis B vaccine - Do we need boosters?
    • Banatvala JE, Damme P. Hepatitis B vaccine-do we need boosters? J Viral Hepat 2003; 10: 1-6.
    • (2003) J Viral Hepat , vol.10 , pp. 1-6
    • Banatvala, J.E.1    Damme, P.2
  • 2
    • 0028916425 scopus 로고
    • Hepatitis B virus immunopathogenesis
    • Chisari FV, Ferrari C. Hepatitis B virus immunopathogenesis. Ann Rev Immunol 1995; 13: 29-60.
    • (1995) Ann Rev Immunol , vol.13 , pp. 29-60
    • Chisari, F.V.1    Ferrari, C.2
  • 3
    • 0028093559 scopus 로고
    • Host immune response and variations in the virus genome: Pathogenesis of liver damage caused by hepatitis B virus
    • Naoumov NV, Eddleston ALWF. Host immune response and variations in the virus genome: pathogenesis of liver damage caused by hepatitis B virus. Gut 1994; 35: 1013-1017.
    • (1994) Gut , vol.35 , pp. 1013-1017
    • Naoumov, N.V.1    Eddleston, A.L.W.F.2
  • 4
    • 0024383213 scopus 로고
    • Identification of HBV variants which cannot produce precore derived HBeAg and may be responsible for severe hepatitis
    • Brunetto MR, Stemler M, Schodel F et al. Identification of HBV variants which cannot produce precore derived HBeAg and may be responsible for severe hepatitis. Ital J Gastroenterol Hepatol 1989; 21: 151-154.
    • (1989) Ital J Gastroenterol Hepatol , vol.21 , pp. 151-154
    • Brunetto, M.R.1    Stemler, M.2    Schodel, F.3
  • 5
    • 0024427902 scopus 로고
    • Mutation preventing formation of hepatitis B e antigen in patients with chronic hepatitis B infection
    • Carman WF, Jacyna MR, Hadziyannis S et al. Mutation preventing formation of hepatitis B e antigen in patients with chronic hepatitis B infection. Lancet 1989; 2: 588-591.
    • (1989) Lancet , vol.2 , pp. 588-591
    • Carman, W.F.1    Jacyna, M.R.2    Hadziyannis, S.3
  • 6
    • 0032954375 scopus 로고    scopus 로고
    • Mechanism of suppression of hepatitis B virus precore RNA transcription by a frequent double mutation
    • Li J, Buckwold VE, Hon MW, Ou JH. Mechanism of suppression of hepatitis B virus precore RNA transcription by a frequent double mutation. J Virol 1999; 73: 1239-1244.
    • (1999) J Virol , vol.73 , pp. 1239-1244
    • Li, J.1    Buckwold, V.E.2    Hon, M.W.3    Ou, J.H.4
  • 7
    • 0029817029 scopus 로고    scopus 로고
    • Effect of a naturally occurring mutation in the hepatitis B virus basal core promoter on precore gene expression and viral replication
    • Buckwold VE, Xu Z, Chen M, Yen TSB, Ou JH. Effect of a naturally occurring mutation in the hepatitis B virus basal core promoter on precore gene expression and viral replication. J Virol 1996; 70: 5845-5851.
    • (1996) J Virol , vol.70 , pp. 5845-5851
    • Buckwold, V.E.1    Xu, Z.2    Chen, M.3    Yen, T.S.B.4    Ou, J.H.5
  • 8
    • 0026527598 scopus 로고
    • Variations in codons 84-101 in the core nucleotide sequence correlate with hepatocellular injury in chronic hepatitis B virus infection
    • Ehata T, Omata M, Yokosuka O, Hosoda K, Ohto M. Variations in codons 84-101 in the core nucleotide sequence correlate with hepatocellular injury in chronic hepatitis B virus infection. J Clin Invest 1992; 89: 332-338.
    • (1992) J Clin Invest , vol.89 , pp. 332-338
    • Ehata, T.1    Omata, M.2    Yokosuka, O.3    Hosoda, K.4    Ohto, M.5
  • 9
    • 0027394588 scopus 로고
    • Mutations in core nucleotide sequence of hepatitis B virus correlate with fulminant and severe hepatitis
    • Ehata T, Omata M, Chuang WL et al. Mutations in core nucleotide sequence of hepatitis B virus correlate with fulminant and severe hepatitis. J Clin Invest 1993; 91: 1206-1213.
    • (1993) J Clin Invest , vol.91 , pp. 1206-1213
    • Ehata, T.1    Omata, M.2    Chuang, W.L.3
  • 10
    • 0029100703 scopus 로고
    • Naturally occurring hepatitis B virus core gene mutations
    • Akarca US, Lok ASF. Naturally occurring hepatitis B virus core gene mutations. Hepatology 1995; 22: 50-60.
    • (1995) Hepatology , vol.22 , pp. 50-60
    • Akarca, U.S.1    Lok, A.S.F.2
  • 11
    • 0027475301 scopus 로고
    • Precore mutations and core clustering mutations in chronic hepatitis B virus infection
    • Chuang WL, Omata M, Ehata T et al. Precore mutations and core clustering mutations in chronic hepatitis B virus infection. Gastroenterology 1993; 104: 263-271.
    • (1993) Gastroenterology , vol.104 , pp. 263-271
    • Chuang, W.L.1    Omata, M.2    Ehata, T.3
  • 12
    • 0028543748 scopus 로고
    • Correlation between HBV preC/C gene mutations and advanced pathologic activity in chronic hepatitis B
    • Luo KX, Yang J, Liang CS, Zhang L. Correlation between HBV preC/C gene mutations and advanced pathologic activity in chronic hepatitis B. Chin J Inter Med 1994; 33: 763-766.
    • (1994) Chin J Inter Med , vol.33 , pp. 763-766
    • Luo, K.X.1    Yang, J.2    Liang, C.S.3    Zhang, L.4
  • 13
    • 0035033218 scopus 로고    scopus 로고
    • Transfer of hepatitis B virus genome by adenovirus vectors into cultured cells and mice: Crossing the species barrier
    • Sprinzl MF, Oberwinkler H, Schaller H, Protzer U. Transfer of hepatitis B virus genome by adenovirus vectors into cultured cells and mice: crossing the species barrier. J Virol 2001; 75: 5108-5118.
    • (2001) J Virol , vol.75 , pp. 5108-5118
    • Sprinzl, M.F.1    Oberwinkler, H.2    Schaller, H.3    Protzer, U.4
  • 15
    • 0025334855 scopus 로고
    • Hepadnavirus envelop proteins regulate covalently closed circular DNA amplification
    • Summers J, Smith PM, Horwich AL. Hepadnavirus envelop proteins regulate covalently closed circular DNA amplification. J Virol 1990; 64: 2819-2824.
    • (1990) J Virol , vol.64 , pp. 2819-2824
    • Summers, J.1    Smith, P.M.2    Horwich, A.L.3
  • 16
    • 0028927825 scopus 로고
    • Method for quantitation of IgG subclass antibodies in mouse serum by enzyme-linked immunosorbent assay
    • Gupta RK, Siber GR. Method for quantitation of IgG subclass antibodies in mouse serum by enzyme-linked immunosorbent assay. J Immunol Method 1995; 181: 75-81.
    • (1995) J Immunol Method , vol.181 , pp. 75-81
    • Gupta, R.K.1    Siber, G.R.2
  • 17
    • 0030000221 scopus 로고    scopus 로고
    • High rate of mutations in the hepatitis B core gene during the immune clearance phase of chronic hepatitis B virus infection
    • Bozkaya H, Ayola B, Lok ASF. High rate of mutations in the hepatitis B core gene during the immune clearance phase of chronic hepatitis B virus infection. Hepatology 1996; 24: 32-37.
    • (1996) Hepatology , vol.24 , pp. 32-37
    • Bozkaya, H.1    Ayola, B.2    Lok, A.S.F.3
  • 18
    • 0033064976 scopus 로고    scopus 로고
    • The mechanism of an immature secretion phenotype of a highly frequent naturally occurring missense mutation at codon 97 of human hepatitis B virus core antigen
    • Yuan TT, Sahu GK, Whitehead WE, Greenberg R, Shih C. The mechanism of an immature secretion phenotype of a highly frequent naturally occurring missense mutation at codon 97 of human hepatitis B virus core antigen. J Virol 1999; 73: 5731-5740.
    • (1999) J Virol , vol.73 , pp. 5731-5740
    • Yuan, T.T.1    Sahu, G.K.2    Whitehead, W.E.3    Greenberg, R.4    Shih, C.5
  • 19
    • 0034000244 scopus 로고    scopus 로고
    • A frequent naturally occurring mutation (P130T) of human hepatitis B virus core antigen is compensatory for immature secretion phenotype of another frequent variant (I97L)
    • Yuan TT, Shih C. A frequent naturally occurring mutation (P130T) of human hepatitis B virus core antigen is compensatory for immature secretion phenotype of another frequent variant (I97L). J Virol 2000; 74: 4929-4932.
    • (2000) J Virol , vol.74 , pp. 4929-4932
    • Yuan, T.T.1    Shih, C.2
  • 20
    • 0036889379 scopus 로고    scopus 로고
    • Replication advantage and host factor-independent phenotypes attributable to a common naturally occurring capsid mutation (I97L) in human hepatitis B virus
    • Suk FM, Lin MH, Newman M et al. Replication advantage and host factor-independent phenotypes attributable to a common naturally occurring capsid mutation (I97L) in human hepatitis B virus. J Virol 2002; 76: 12069-12077.
    • (2002) J Virol , vol.76 , pp. 12069-12077
    • Suk, F.M.1    Lin, M.H.2    Newman, M.3
  • 21
    • 0033808521 scopus 로고    scopus 로고
    • Low-level secretion of human hepatitis B virus caused by two independent, naturally occurring mutations (P5T and L60V) in the capsid protein
    • Pogam SL, Yuan TT, Sahu GK, Chatterjee S, Shih C. Low-level secretion of human hepatitis B virus caused by two independent, naturally occurring mutations (P5T and L60V) in the capsid protein. J Virol 2000; 74: 9099-9105.
    • (2000) J Virol , vol.74 , pp. 9099-9105
    • Pogam, S.L.1    Yuan, T.T.2    Sahu, G.K.3    Chatterjee, S.4    Shih, C.5
  • 22
    • 0029951519 scopus 로고    scopus 로고
    • A replication-defective human adenovirus recombinant serve as a highly efficacious vaccine carrier
    • Xiang ZQ, Yang YP, Wilson JM, Ertl HCJ. A replication-defective human adenovirus recombinant serve as a highly efficacious vaccine carrier. Virology 1996; 219: 220-227.
    • (1996) Virology , vol.219 , pp. 220-227
    • Xiang, Z.Q.1    Yang, Y.P.2    Wilson, J.M.3    Ertl, H.C.J.4
  • 23
    • 0029163410 scopus 로고
    • High level expression of the measles virus nucleocapsid protein by using a replication-deficient adenovirus vector: Induction of an MHC-1-restricted CTL response and protection in a murine model
    • Fooks AR, Schadeck E, Liebert UG et al. High level expression of the measles virus nucleocapsid protein by using a replication-deficient adenovirus vector: induction of an MHC-1-restricted CTL response and protection in a murine model. Virology 1995; 210: 456-465.
    • (1995) Virology , vol.210 , pp. 456-465
    • Fooks, A.R.1    Schadeck, E.2    Liebert, U.G.3
  • 24
    • 0023804209 scopus 로고
    • Comparative immunogenicity of hepatitis B virus core and e antigens
    • Milich DR, McLachlan A, Stahl S et al. Comparative immunogenicity of hepatitis B virus core and E antigens. J Immunol 1988; 141: 3617-3624.
    • (1988) J Immunol , vol.141 , pp. 3617-3624
    • Milich, D.R.1    McLachlan, A.2    Stahl, S.3
  • 25
    • 0029799729 scopus 로고    scopus 로고
    • Hepatitis B virus core and e antigen: Immune recognition and use as a vaccine carrier moiety
    • Schodel F, Peterson D, Milich D. Hepatitis B virus core and e antigen: immune recognition and use as a vaccine carrier moiety. Intervirology 1996; 39: 104-110.
    • (1996) Intervirology , vol.39 , pp. 104-110
    • Schodel, F.1    Peterson, D.2    Milich, D.3
  • 26
    • 0024353079 scopus 로고
    • TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • Mosmann TR, Coffman RL. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 1989; 7: 145-173.
    • (1989) Annu Rev Immunol , vol.7 , pp. 145-173
    • Mosmann, T.R.1    Coffman, R.L.2
  • 27
    • 0025216937 scopus 로고
    • Lymphokine control of in vivo immunogloblin isotype selection
    • Finkelman FD, Holmes J, Katona M et al. Lymphokine control of in vivo immunogloblin isotype selection. Annu Rev Immunol 1990; 8: 303-333.
    • (1990) Annu Rev Immunol , vol.8 , pp. 303-333
    • Finkelman, F.D.1    Holmes, J.2    Katona, M.3
  • 28
    • 0026040543 scopus 로고
    • Hepatitis B virus antigen-specific T-cell activation in patients with acute and chronic hepatitis B
    • Jung M, Spengler U, Schraut W et al. Hepatitis B virus antigen-specific T-cell activation in patients with acute and chronic hepatitis B. J Hepatol 1991; 13: 310-317.
    • (1991) J Hepatol , vol.13 , pp. 310-317
    • Jung, M.1    Spengler, U.2    Schraut, W.3
  • 29
    • 0026801058 scopus 로고
    • Cellular immune responses of peripheral blood mononuclear cells to HBV antigens during chronic and acute HBV infection
    • Wakita T, Kakumu S, Yoshioka K, Ishikawa T, Ito Y, Shinagawa T. Cellular immune responses of peripheral blood mononuclear cells to HBV antigens during chronic and acute HBV infection. Digestion 1992; 52: 26-33.
    • (1992) Digestion , vol.52 , pp. 26-33
    • Wakita, T.1    Kakumu, S.2    Yoshioka, K.3    Ishikawa, T.4    Ito, Y.5    Shinagawa, T.6
  • 30
    • 0029134818 scopus 로고
    • Proliferative response of CD4+ T cells and HBV clearance in chronic hepatitis B with and without HBe-minus HBV mutants
    • Lohr HF, Weber W, Schlaak JF et al. Proliferative response of CD4+ T cells and HBV clearance in chronic hepatitis B with and without HBe-minus HBV mutants. Hepatology 1995; 22: 61-68.
    • (1995) Hepatology , vol.22 , pp. 61-68
    • Lohr, H.F.1    Weber, W.2    Schlaak, J.F.3
  • 31
    • 0027333348 scopus 로고
    • Tickling the TCR: Selective T-cell functions stimulated by altered peptide ligands
    • Evavold BD, Sloan-Lancaster J, Allen PM. Tickling the TCR: selective T-cell functions stimulated by altered peptide ligands. Immunol Today 1993; 14: 602-609.
    • (1993) Immunol Today , vol.14 , pp. 602-609
    • Evavold, B.D.1    Sloan-Lancaster, J.2    Allen, P.M.3
  • 32
    • 0030903872 scopus 로고    scopus 로고
    • Hepatitis B virus core protein mutations are concentrated in B cell epitopes in progressive disease and in T helper cell epitopes during clinical remission
    • Carman WF, Boner W, Fattovich G et al. Hepatitis B virus core protein mutations are concentrated in B cell epitopes in progressive disease and in T helper cell epitopes during clinical remission. J Infect Dis 1997; 175: 1093-1100.
    • (1997) J Infect Dis , vol.175 , pp. 1093-1100
    • Carman, W.F.1    Boner, W.2    Fattovich, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.