Structure-property relationships and models of controlled drug delivery of biodegradable poly (D, L-lactic acid) microspheres

Chinese Journal of Chemical Engineering

Volumn 12, Issue 6, 2004, Pages 869-876

  Pan, Jizheng ^a   Zhang, Lijuan ^a   Qian, Yu ^a  

^a SOUTH CHINA UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Controlled release; Drug delivery; Microspheres; Model; Nifedipine; Solvent evaporation; Structure property relationships

Indexed keywords

BIODEGRADATION; HYDROPHOBICITY; MATHEMATICAL MODELS; MORPHOLOGY; SOLVENTS;

CONTROLLED RELEASE; MICROSPHERES; NIFEDIPINE; SOLVENT EVAPORATION; STRUCTURE PROPERTY RELATIONSHIPS;

CONTROLLED DRUG DELIVERY;

MEDICAL APPLICATION;

EID: 14744296994     PISSN: 10049541     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Peppas, L.B., Recent advances on the use of biodegradable microparticles and nanoparticles in controlled drug delivery, International Journal of Pharmaceutics, 116, 1-9 (1995).
2. Anderson, J.M., Shive, M.S., Biodegradation and bio-compatibility of PLA and PLGA microspheres, Advanced Drug Delivery Reviews, 28, 524 (1997).
3. O'Donnell, P.B., McGinity, J.W., Preparation of micro-spheres by the solvent evaporation technique, Advanced Drug Delivery Reviews, 28, 25-42 (1997).
4. Guyot, M., Fawaz, F., Nifedipine loaded-polymeric micro-spheres: Preparation and physical characteristics, International Journal of Pharmaceutics, 175, 61-74 (1998).
5. Berkland, C., King, M., Cox, A., Kim, K., Pack, D.W., Precise control of PLG microshpere size provides enhanced control of drug release rate, Journal of Controlled Release, 82, 137-147 (2002).
6. Wong, H.M., Wang, J.J., Wang, C., In vitro sustained release of human immunoglobulin G from biodegradable microspheres, Ind. Eng. Chem. Res., 40, 933-948 (2001).
7. Hombeiro-Perez, M., Zinutti, C., Lamprecht, A., Ubrich, N., Astier, A., Hoffman, M., Bodmeier, R., Maincent, P., The preparation and evaluation of poly (ε-caprolactone) microparticles containing both a lipophilic and a hydrophilic drug, Journal of Controlled Release, 65, 429-438 (2000).
8. Hombeiro-Perez, M., Siepmann, J., Zinutti, C., Lamprecht, A., Ubrich, N., Hoffman, M., Bodmeier, R., Maincent, P., Non-degradable microparticles containing a hydrophilic and/or a lipophilic drug: Preparation, characterization and drug release modeling, Journal of Controlled Release, 65, 429-438 (2003).
9. Sood, A., Panchagnula, R., Design of controlled release delivery systems using a modified pharmacokinetic approach: A case study for drugs having a short elimination half-life and a narrow therapeutic index, International Journal of Pharmaceutics, 261, 27-41 (2003).
10. Polakovic, M., Corner, T., Gref, R., Dellacherie, E., Lidocaine-loaded biodegradable nanospheres. E. Modeling of drug release, Journal of Controlled Release, 60, 169-177 (1999).
11. Paulo, C., Jose, M.S.L., Modeling and comparison of dissolution profiles, European Journal of Pharmaceutical Sciences, 13, 123-133 (2001).
12. Faisant, N., Siepmann, J., Benoit, J.P., PLGA-based microparticles: Elucidation of mechanisms and a new, simple mathematical model quantifying drug release, European Journal of Pharmaceutical Sciences, 15, 355-366 (2002).
13. Zhang, M.P., Yang, Z., Chow, L., Wang, C., Simulation of drug release from biodegradable polymeric microspheres with bulk and surface erosions, Journal of Pharmaceutical Sciences, 92, 2040-2056 (2003).
14. Crank, J., The Mathematics of Diffusion, 2nd ed. Carendon Press, Oxford, U.K., (1975).
15. Berkland, C., Kim, K., Pack, D.W., Fabrication of PLG microspheres with precisely controlled and monodisperse size distributions, Journal of Controlled Release, 73, 59-74 (2001).