Molecular predictor and promising target: Will EGFR now become a star in radiotherapy?

Radiotherapy and Oncology

Volumn 74, Issue 2, 2005, Pages 89-91

  Lammering, Guido ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; MONOCLONAL ANTIBODY; PROTEIN TYROSINE KINASE INHIBITOR;

BREAST CARCINOMA; CANCER CHEMOTHERAPY; CANCER CONTROL; CANCER GROWTH; CANCER LOCALIZATION; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER RELAPSE; CANCER SURVIVAL; CLINICAL TRIAL; DRUG TARGETING; EDITORIAL; GLIOBLASTOMA; HEAD AND NECK CARCINOMA; HUMAN; MOLECULAR BIOLOGY; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; RADIATION DOSE FRACTIONATION; RADIOSENSITIVITY; RADIOSENSITIZATION; RECTUM CARCINOMA; SOLID TUMOR; SQUAMOUS CELL CARCINOMA; TREATMENT OUTCOME; UTERINE CERVIX CARCINOMA;

EID: 14744285675     PISSN: 01678140     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.radonc.2005.01.004     Document Type: Editorial

References (29)

1. K.K. Ang, N.H. Andratschke, and L. Milas Epidermal growth factor receptor and response of head-and-neck carcinoma to therapy Int J Radiat Oncol Biol Phys 58 2004 959 965
2. F.G. Barker II, M.L. Simmons, and S.M. Chang EGFR overexpression and radiation response in glioblastoma multiforme Int J Radiat Oncol Biol Phys 51 2001 410 418
3. M. Baumann, T. Holscher, and A.C. Begg Towards genetic prediction of radiation responses: ESTRO's GENEPI project Radiother Oncol 69 2003 121 125
4. M. Baumann, M. Krause, and D. Zips Selective inhibition of the epidermal growth factor receptor tyrosine kinase by BIBX1382BS improves growth delay but not local control after fractionated irradiation in human FaDu squamous cell carcinoma in nude mice Int J Radiat Biol 79 2003 547 559
5. M. Baumann, and M. Krause Targeting the epidermal growth factor receptor in radiotherapy: radiobiological mechanisms, preclinical and clinical results Radiother Oncol 72 2004 257 273
6. J.A. Bonner, P.M. Harari, and J.L. Giralt Cetuximab (Erbitux TM) prolongs survival in patients with locally advanced squamous cell carcinoma of the head and neck; a phase III study of high dose radiation therapy with and without cetuximab Proc Am Soc Clin Oncol (abstract) 2004 5507
7. J.G. Eriksen, F.M. Buffa, J. Alsner, T. Steiniche, S.M. Bentzen, and J. Overgaard Molecular profiles as predictive marker for the effect of overall treatment time of radiotherapy in supraglottic larynx squamous cell carcinomas Radiother Oncol 71 2004 275 282
8. J.G. Eriksen, T. Steiniche, and J. Askaa The prognostic value of epidermal growth factor receptor is related to tumor differentiation and the overall treatment time of radiotherapy in squamous cell carcinomas of the head and neck Int J Radiat Oncol Biol Phys 58 2004 561 566
9. J.G. Eriksen, T. Steiniche, and J. Overgaard The influence of epidermal growth factor receptor and tumor differentiation on the response to accelerated radiotherapy of squamous cell carcinomas of the head and neck in the randomized DAHANC 6 and 7 study Radiother Oncol 74 2005 93 100
10. J. Fisher-Colbrie, A. Witt, and H. Heinzl EGFR and steroid receptors in ovarian carcinoma: comparison with prognostic parameters and outcome of patients Anticancer Res 17 1997 613 620
11. J. Giralt, A. Eraso, and M. Asmengol Epidermal growth factor receptor is a predictor of tumor response in locally advanced rectal cancer patients treated with preoperative radiotherapy Int J Radiation Oncol Biol Phys 54 2002 1460 1465
12. J. Giralt, M. Heras de las, and L. Cerezo The expression of epidermal growth factor receptor results in a worse prognosis for patients with rectal cancer treated with preoperative radiotherapy: a multicenter, retrospective analysis Radiother Oncol 74 2005 101 108
13. S.M. Huang, J. Li, E.A. Armstrong, and P.M. Harari Modulation of radiation response and tumor-induced angiogenesis after epidermal growth factor receptor inhibition by ZD1839 (Iressa) Cancer Res 62 2002 4300 4306
14. J.G. Klijn, M.P. Look, and H. Portengen The prognostic value of epidermal growth factor receptor (EGFR) in primary breast cancer: results of a 10-year follow-up study Breast Cancer Res Treat 29 1994 73 83
15. M. Krause, F. Hessel, D. Zips, F. Hilberg, and M. Baumann Adjuvant inhibition of the epidermal growth factor receptor after fractionated irradiation of FaDu human squamous cell carcinoma Radiother Oncol 72 2004 95 101
16. M. Krause, C. Schuetze, and C. Petersen Different classes of EGFR inhibitors may have different potential to imporve local tumour control after fractionated irradiation: a study on C225 in FaDu hSCC Radiother Oncol 74 2005 109 115
17. G. Lammering, K. Valerie, P.S. Lin, T.H. Hewit, and R.K. Schmidt-Ullrich Radiation-induced activation of a common variant of EGFR confers enhanced radioresistance Radiother Oncol 72 2004 267 273
18. G. Lammering, T.H. Hewit, and W.T. Hawkins Epidermal growth factor receptor as a gentic therapy target for carcinoma cell radiosensitization J Natl Cancer Inst 93 2001 921 929
19. M. Maurizi, G. Almadori, and G. Ferrandina Prognostic significance of epidermal growth factor receptor in laryngeal squamous cell carcinoma Br J Cancer 74 1996 1253 1257
20. L. Milas, K. Mason, and N. Hunter In vivo enhancement of tumor radioresponse by C225 antiepidermal growth factor receptor antibody Clin Cancer Res 6 2000 701 708
21. J.G. Paez, P.A. Janne, and J.C. Lee EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy Science 304 2004 1497 1500
22. M. Pillai, P.G. Jayaprakash, and M. Nai Tumour-proliferative fraction and growth factor expression as markers of tumour response to radiotherapy in cancer of the uterine cervix J Cancer Res Clin Oncol 124 1998 456 461
23. H.P. Rodemann, M. Baumann, S. Bodis, and E. Dikomey Molecular radiation biology/oncology Radiother Oncol 72 2004 247 249
24. R.K. Schmidt-Ullrich, J.N. Contessa, and P. Dent Molecular mechanisms of radiation- induced accelerated repopulation Radiat Oncol Invest 7 1999 321 330
25. R.K. Schmidt-Ullrich, J.N. Contessa, G. Lammering, and G.P. Amorino Receptor tyrosine kinases and cellular responses to ionizing radiation Oncogene 22 2003 5855 5865
26. R.K. Schmidt-Ullrich, K.C. Valerie, W. Chan, and D. McWilliams Altered expression of epidermal growth factor receptor and estrogen receptor MCF-7 cells after single and repeated radiation exposures Int J Radiat Oncol Biol Phys 29 1994 813 819
27. G. Selvaggi, S. Novello, and V. Torri Epidermal growth factor receptor overexpression correlates with a poor prognosis in completely resected non-small cell lung cancer Ann Oncol 15 2004 28 32
28. N. Shinojima, K. Tada, and S. Shiraishi Prognostic value of epidermal growth factor receptor in patients with glioblastoma multiforme Cancer Res 63 2003 6962 6970
29. M. Toulany, K. Dittmann, M. Baumann, and H.P. Rodemann Radiosensitization of Ras-mutated human tumor cells in vitro by the specific EGF receptor antagonist BIBX1382BS Radiother Oncol 74 2005 117 129