Improved posthypoxic recovery in vitro on treatment with drugs used for secondary stroke prevention

Neuropharmacology

Volumn 48, Issue 4, 2005, Pages 558-565

  Huber, Roman ^a   Riepe, Matthias W ^a,b  

^a UNIVERSITY OF ULM   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

HMG CoA reductase inhibition; Hypoxia; Neuroprotection; Platelet inhibition

Indexed keywords

ACETYLSALICYLIC ACID; ATORVASTATIN; CLOPIDOGREL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; TICLOPIDINE;

AEROBIC METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOFLUORESCENCE; BODY WEIGHT; BRAIN HYPOXIA; BRAIN PROTECTION; BRAIN SLICE; CONTROLLED STUDY; DRUG EFFECT; HIPPOCAMPUS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SECONDARY PREVENTION; SPIKE; STROKE; THROMBOCYTE AGGREGATION INHIBITION; TIME;

EID: 14744282749     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2004.12.002     Document Type: Article

References (40)

1. W.H. Abou-Khalil, L.O. Lim, A.A. Yunis, and S. Abou-Khalil Effects of ticlopidine, a new platelet antiaggregating agent, and its analogues on mitochondrial metabolism. Oxidative phosphorylation, protein synthesis and DNA polymerase activity Biochem. Pharmacol. 33 1984 3893 3898
2. S. Abou-Khalil, W.H. Abou-Khalil, and A.A. Yunis Mechanism of interaction of ticlopidine and its analogues with the energy-conserving mechanism in mitochondria Biochem. Pharmacol. 35 1986 1855 1859
3. J.W. Akkerman, G. Gorter, H. Soons, and H. Holmsen Close correlation between platelet responses and adenylate energy charge during transient substrate depletion Biochim. Biophys. Acta 760 1983 34 41
4. S. Amin-Hanjani, N.E. Stagliano, M. Yamada, P.L. Huang, J.K. Liao, and M.A. Moskowitz Mevastatin, an HMG-CoA reductase inhibitor, reduces stroke damage and upregulates endothelial nitric oxide synthase in mice Stroke 32 2001 980 986
5. M. Büchner, R. Huber, and M.W. Riepe Trans-synaptic increase of hypoxic tolerance in hippocampus upon physical challenge with two-photon microscopy Hippocampus 12 2002 765 773
6. G. De Pinieux, P. Chariot, M. Ammi-Said, F. Louarn, J.L. Lejonc, A. Astier, B. Jacotot, and R. Gherardi Lipid-lowering drugs and mitochondrial function: effects of HMG-CoA reductase inhibitors on serum ubiquinone and blood lactate/pyruvate ratio Br. J. Clin. Pharmacol. 42 1996 333 337
7. G. Dorr, G. Schmidt, M. Grafe, V. Regitz-Zagrosek, and E. Fleck Effects of combined therapy with clopidogrel and acetylsalicylic acid on platelet glycoprotein expression and aggregation J. Cardiovasc. Pharmacol. 39 2002 523 532
8. M. Endres, U. Laufs, Z. Huang, T. Nakamura, P. Huang, M.A. Moskowitz, and J.K. Liao Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase Proc. Natl. Acad. Sci. USA 95 1998 8880 8885
9. M. Essig, G. Nguyen, D. Prie, B. Escoubet, J.D. Sraer, and G. Friedlander 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors increase fibrinolytic activity in rat aortic endothelial cells. Role of geranylgeranylation and Rho proteins Circ. Res. 83 1998 683 690
10. S. Feig, and P. Lipton N-methyl-d-aspartate receptor activation and Ca2+ account for poor pyramidal cell structure in hippocampal slices J. Neurochem. 55 1990 473 483
11. D.M. Gibson, N.J. Bron, A. Richens, N.J. Hounslow, A.J. Sedman, and L.R. Whitfield Effect of age and gender on pharmacokinetics of atorvastatin in humans J. Clin. Pharmacol. 36 1996 242 246
12. M. Grilli, M. Pizzi, M. Memo, and P. Spano Neuroprotection by aspirin and sodium salicylate through blockade of NF-κB activation Science 274 1996 1383 1385
13. R. Hellweg, C.A.F. von Arnim, M. Büchner, R. Huber, and M.W. Riepe Neuroprotection and neuronal dysfunction upon repetitive inhibition of oxidative phosphorylation Exp. Neurol. 183 2003 346 354
14. R. Huber, K. Kasischke, A.C. Ludolph, and M.W. Riepe Increase of cellular hypoxic tolerance by erythromycin and other antibiotics Neuroreport 10 1999 1543 1546
15. R. Huber, M. Buchner, H. Li, M. Schlieter, A.D. Speerfeld, and M.W. Riepe Protein binding of NADH on chemical preconditioning J. Neurochem. 75 2000 329 335
16. S.E. Husted, A.K. Pedersen, T. Petersen, and E. Geday Systemic availability of acetylsalicylic acid in normal men and women and its effect on in vitro platelet aggregability Eur. J. Clin. Pharmacol. 24 1983 679 682
17. Influence of pravastatin and plasma lipids on clinical events in the West of Scotland Coronary Prevention Study (WOSCOPS) Circulation 97 1998 1440 1445
18. K. Kasischke, A.C. Ludolph, and M.W. Riepe NMDA-antagonists reverse increased hypoxic tolerance by preceding chemical hypoxia Neurosci. Lett. 214 1996 175 178
19. K. Kasischke, R. Huber, H. Li, M. Timmler, and M.W. Riepe Primary hypoxic tolerance and chemical preconditioning during estrus cycle in mice Stroke 30 1999 1256 1262
20. S.E. Kjeldsen, R.E. Kolloch, G. Leonetti, J.M. Mallion, A. Zanchetti, D. Elmfeldt, I. Warnold, and L. Hansson Influence of gender and age on preventing cardiovascular disease by antihypertensive treatment and acetylsalicylic acid. The HOT study. Hypertension Optimal Treatment J. Hypertens. 18 2000 629 642
21. T.K. Lee, Y.C. Chen, and T.L. Kuo Comparison of the effect of acetylsalicylic acid on platelet function in male and female patients with ischemic stroke Thromb. Res. 47 1987 295 304
22. E.H. Lo, T. Dalkara, and M.A. Moskowitz Mechanisms, challenges and opportunities in stroke Nat. Rev. Neurosci. 4 2003 399 415
23. M.E. Martens, and C.P. Lee Reye's syndrome: salicylates and mitochondrial functions Biochem. Pharmacol. 33 1984 2869 2876
24. P.D. Martin, A.L. Dane, O.M. Nwose, D.W. Schneck, and M.J. Warwick No effect of age or gender on the pharmacokinetics of rosuvastatin: a new HMG-CoA reductase inhibitor J. Clin. Pharmacol. 42 2002 1116 1121
25. M.A. Moro, J. De Alba, A. Cardenas, J. De Cristobal, J.C. Leza, I. Lizasoain, M.J. Diaz-Guerra, L. Bosca, and P. Lorenzo Mechanisms of the neuroprotective effect of aspirin after oxygen and glucose deprivation in rat forebrain slices Neuropharmacology 39 2000 1309 1318
26. K. Moshfegh, M. Redondo, F. Julmy, W.A. Wuillemin, M.U. Gebauer, A. Haeberli, and B.J. Meyer Antiplatelet effects of clopidogrel compared with aspirin after myocardial infarction: enhanced inhibitory effects of combination therapy J. Am. Coll. Cardiol. 36 2000 699 705
27. M.J. Quinn, and D.J. Fitzgerald Ticlopidine and clopidogrel Circulation 100 1999 1667 1672
28. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S) Lancet 344 1994 1383 1389
29. M.W. Riepe, K. Kasischke, C.A. Gericke, A. Lowe, and R. Hellweg Increase of hypoxic tolerance in rat hippocampal slices following 3-nitropropionic acid is not mediated by endogenous nerve growth factor Neurosci. Lett. 211 1996 9 12
30. M.W. Riepe, W.N. Niemi, D. Megow, A.C. Ludolph, and D.O. Carpenter Mitochondrial oxidation in rat hippocampus can be preconditioned by selective chemical inhibition of succinic dehydrogenase Exp. Neurol. 138 1996 15 21
31. M.W. Riepe, F. Esclaire, K. Kasischke, S. Schreiber, H. Nakase, O. Kempski, A.C. Ludolph, U. Dirnagl, and J. Hugon Increased hypoxic tolerance by chemical inhibition of oxidative phosphorylation: "chemical preconditioning" J. Cereb. Blood Flow Metab. 17 1997 257 264
32. M.W. Riepe, K. Kasischke, and A. Raupach Acetylsalicylic acid increases tolerance against hypoxic and chemical hypoxia Stroke 28 1997 2006 2011
33. M.W. Riepe, and A.C. Ludolph Chemical preconditioning: a cytoprotective strategy Mol. Cell. Biochem. 174 1997 249 254
34. F.M. Sacks, M.A. Pfeffer, L.A. Moye, J.L. Rouleau, J.D. Rutherford, T.G. Cole, L. Brown, J.W. Warnica, J.M. Arnold, C.C. Wun, B.R. Davis, and E. Braunwald The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators N. Engl. J. Med. 335 1996 1001 1009
35. K. Satoh, and K. Ichihara Effects of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on mitochondrial respiration in ischemic rat hearts Eur. J. Pharmacol. 292 1995 271 275
36. J. Shepherd, S.M. Cobbe, I. Ford, C.G. Isles, A.R. Lorimer, P.W. Macfarlane, J.H. McKillop, and C.J. Packard Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group N. Engl. J. Med. 333 1995 1301 1307
37. S. Sugiyama HMG CoA reductase inhibitor accelerates aging effect on diaphragm mitochondrial respiratory function in rats Biochem. Mol. Biol. Int. 46 1998 923 931
38. A.J. Verhoeven, G. Gorter, M.E. Mommersteeg, and J.W. Akkerman The energetics of early platelet responses. Energy consumption during shape change and aggregation with special reference to protein phosphorylation and the polyphosphoinositide cycle Biochem. J. 228 1985 451 462
39. H. Vinazzer, J. Putter, and D. Loew Influence of intravenously administered acetylsalicylic acid on platelet functions. A pharmacodynamic and pharmacokinetic study Haemostasis 4 1975 12 22
40. M.W. Whitehouse, and J.M. Haslam Ability of some antirheumatic drugs to uncouple oxidative phosphorylation Nature 196 1962 1323 1324