The mechanism of microsatellite instability is different in synchronous and metachronous colorectal cancer

Journal of Gastrointestinal Surgery

Volumn 9, Issue 3, 2005, Pages 329-335

  Velayos, Fernando S ^a   Lee, Suk Hwan ^b   Qiu, Hongming ^b   Dykes, Sharon ^b   Yiu, Raymond ^b   Terdiman, Jonathan P ^a   Garcia Aguilar, Julio ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Colorectal cancer; Epigenetic modification; Hereditary nonpolyposis colorectal cancer; Metachronous colorectal cancer; Microsatellite instability; MLH1; MSH2; Multiple tumors; Promoter methylation; Synchronous colorectal cancer

Indexed keywords

PROTEIN MLH1; PROTEIN MSH2;

ADULT; AGED; ARTICLE; CANCER DIAGNOSIS; CANCER SCREENING; CANCER SURGERY; CARCINOGENESIS; COLORECTAL CANCER; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA METHYLATION; FEMALE; FREQUENCY ANALYSIS; HETEROZYGOSITY LOSS; HUMAN; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; METACHRONOUS COLORECTAL CANCER; MICROSATELLITE INSTABILITY; MOLECULAR MECHANICS; PATIENT SELECTION; POPULATION RESEARCH; PROMOTER REGION; PROTEIN EXPRESSION; STATISTICAL SIGNIFICANCE; SYNCHRONOUS COLORECTAL CANCER; TUMOR DIAGNOSIS; UNIVERSITY HOSPITAL;

EID: 14744281516     PISSN: 1091255X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gassur.2004.05.007     Document Type: Article

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