Exercise-induced expression of heme oxygenase-1 in human lymphocytes

Free Radical Research

Volumn 39, Issue 1, 2005, Pages 63-69

  Thompson, Dylan ^a   Basu Modak, Sharmila ^b   Gordon, Matthew ^b   Poore, Sam ^a   Markovitch, Daniella ^a   Tyrrell, Rex M ^b  

^a UNIVERSITY OF BATH   (United Kingdom)

^b University of Bath   (United Kingdom)

Author keywords

Free radicals; Gene expression; Inflammation; Leukocytes; Oxidative stress; Physical activity

Indexed keywords

HEME OXYGENASE 1; MESSENGER RNA;

ADULT; ARTICLE; CONTROLLED STUDY; ENZYME ASSAY; EXERCISE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; LYMPHOCYTE; MALE; NORMAL HUMAN; OXYGEN CONSUMPTION; PHYSICAL ACTIVITY; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REST; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; RUNNING; WESTERN BLOTTING;

ADULT; ANTI-INFLAMMATORY AGENTS; BLOTTING, WESTERN; EXERCISE; FREE RADICALS; GENE EXPRESSION REGULATION; HEME OXYGENASE (DECYCLIZING); HEME OXYGENASE-1; HUMANS; INFLAMMATION; INTERLEUKIN-6; LEUKOCYTES; LYMPHOCYTES; MALE; MEMBRANE PROTEINS; OXIDATIVE STRESS; OXYGEN; RANDOM ALLOCATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; RNA, MESSENGER; TIME FACTORS;

EID: 14744275725     PISSN: 10715762     EISSN: None     Source Type: Journal    
DOI: 10.1080/10715760400022327     Document Type: Article

References (37)

1. Vile GF, Basu-Modak S, Waltner C, Tyrrell RM. Heme oxygenase 1 mediates an adaptive response to oxidative stress in human skin fibroblasts. Proc Natl Acad Sci 1994;91:2607-2610.
2. Poss KD, Tonegawa S. Reduced stress defense in heme oxygenase 1-deficient cells. Proc Natl Acad Sci 1997;94:10925-10930.
3. Rothfuss A, Radermacher P, Speit G. Involvement of heme oxygenase-1 (HO-1) in the adaptive protection of human lymphocytes after hyperbaric oxygen (HBO) treatment. Carcinogenesis 2001;22(12):1979-1985.
4. Reeve V, Tyrrell R. Heme oxygenase induction mediates the photoimmunoprotective activity of UVA radiation in the mouse. Proc Natl Acad Sci 1999;96:9317-9321.
5. Willis D, Moore AR, Frederick R, Willoughby DA. Heme oxygenase: A novel target for the modulation of the inflammatory response. Nat Med 1996;2(1):87-90.
6. Wagener F, Volk HD, Willis D, Abraham NG, Soares MP, Adema GJ, Figdor CG. Different faces of the heme - heme oxygenase system in inflammation. Pharmacol Rev 2003;55(3):551-571.
7. Applegate LA, Luscher P, Tyrrell RM. Induction of heme oxygenase: A general response to oxidant stress in cultured mammalian cells. Cancer Res 1991;51:974-978.
8. Morse D, Choi AMK. Heme oxygenase-l - The "emerging molecule" has arrived. Am J Respir Cell Mol Biol 2002;27(1):8-16.
9. Jackson M, Edwards R, Symons M. Electron spin resonance studies of intact mammalian skeletal muscle. Biochim Biophys Acta 1985;847:185-190.
10. Thompson D, Williams C, Garcia-Roves P, McGregor S, McArdle F, Jackson MJ. Post-exercise vitamin C supplementation and recovery from demanding exercise. Eur J Appl Physiol 2003;89:393-400.
11. Thompson D, Williams C, McGregor SJ, Nicholas CW, McArdle F, Jackson MJ, Powell JR. Prolonged vitamin C supplementation and recovery from demanding exercise. Int J Sport Nutr Exerc Metab 2001;11(4):466-481.
12. McArdle A, Pattwell D, Vasilaki A, Griffiths RD, Jackson MJ. Contractile activity-induced oxidative stress: Cellular origin and adaptive responses. Am J Physiol 2001;280:C621-C627.
13. Niess A, Passek F, Lorenz I, chneider E, Dickhuth H, Northoff H, Fehrenbach E. Expression of the antioxidant stress protein heme oxygenase-1 (HO-1) in human leukocytes. Free Radic Biol Med 1999;26:184-192.
14. Williams C, Nute M, Broadbank L, Vinall S. Influence of fluid intake on endurance running performance. Eur J Appl Physiol 1990;60:112-119.
15. Borg G. Psychophysical bases of perceived exertion. Med Sci Sports Exerc 1982;14(5):377-381.
16. Basu-Modak S, Gordon MJ, Dobson LH, Spencer JPE, Rice-Evans C, Tyrrell RM. Epicatechin and its methylated metabolite attenuate UVA-induced oxidative damage to human skin fibroblasts. Free Radic Biol Med 2003;35(8):910-921.
17. Bradford MM. A rapid and simple method for the quantitation of microgram quantities of protein utilising the principle of protein-dye binding. Anal Biochem 1976;72:248-254.
18. Niess A, Diskhuth H, Northoff H, Fehrenbach E. Free radicals and oxidative stress in exercise - immunological aspects. Exerc Immunol Rev 1999;5:22-56.
19. Otterbein LE, Bach FH, Alam J, Soares M, Tao Lu H, Wysk M, Davis RJ, Flavell RA, Choi AMK. Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nat Med 2000;6(4):422-428.
20. Wagener FADTG, Eggert A, Boerman OC, Oyen WJG, Verhofstad A, Abraham NG, Adema G, van Kooyk Y, de Witte T, Figdor CG. Heme is a potent inducer of inflammation in mice and is counteracted by heme oxygenase. Blood 2001;98:1802-1811.
21. Pedersen B, Ostrowski K, Rohde T, Bruunsgaard H. The cytokine response to strenuous exercise. Can J Physiol Pharmacol 1998;76:505-511.
22. Abraham NG, Drummond GS, Lutton JD, Kappas A. The biological significance and physiological role of heme oxygenase. Cell Physiol Biochem 1996;6:129-168.
23. Miller B, Pate R, Burgess W. Foot impact force and intravascular haemolysis during distance running. Int J Sports Med 1988;9(1):56-60.
24. Pattwell D, McArdle A, Griffiths RD, Jackson MJ. Measurement of free radical production by in vivo microdialysis during ischaemia/reperfusion injury to skeletal muscle. Free Radic Biol Med 2001;30(9):979-985.
25. Bailey DM, Davies B, Young IS, Jackson MJ, Davison GW, Isaacson R, Richardson RS. EPR spectroscopic detection of free radical outflow from an isolated muscle bed in exercising humans. J Appl Physiol 2003;94(5):1714-1718.
26. Alam, J. Igatishi, K. Immenshuh, S. Shibahara, S. and Tyrrell, R.M. (in Press) Regulation of the heme oxygenase-1 gene: Recent advances and highlights from the international conference (Uppsala, 2003) on heme oxygenase. Antioxid. Redox Signal.
27. Weiss S. Tissue destruction by neutrophils. N Engl J Med 1989;320(6):365-376.
28. Halliwell B, Gutteridge JMC. Free radicals in biology and medicine. Oxford Science; 1999.
29. Tyrrell RM, Basu-Modak S. Transient enhancement of heme oxygenase 1 mRNA accumulation: A marker of oxidative stress to eukaryotic cells. Methods Enzymol 1994;234:224-235.
30. Dennery PA, Wong HE, Sridhar KJ, Rodgers PA, Sim JE, Spitz DR. Differences in basal and hyperoxia-associated HO expression in oxidant-resistant hamster fibroblasts. Am J Physiol 1996;271:L672-L679.
31. Honda S, Hjelmeland LM, Handa JT. The use of hyperoxia to induce-chronic mild oxidative stress in RPE cells in vitro. Mol Vis 2001;7:63-70.
32. Obermuller-Jevic UC, Francz PI, Frank J, Flaccus A, Biesalski HK. Enhancement of the UVA induction of haem oxygenase-1 expression by β-carotene in human skin fibroblasts. FEBS lett 1999;460:212-216.
33. Offord E, van Poppel G, Tyrrell R. Markers of oxidative damage and antioxidant protection: Current status and relevance to disease. Free Radic Res 2000;33:S5-S19.
34. Griffiths HR, Moller L, Bartosz G, Bast A, Bertoni-Freddari C, Collins A, Cooke M, Coolen S, Haenen G, Hoberg A-M, Loft S, Lunec J, Olinski R, Parry J, Pompella A, Poulsen H, Verhagen H, Astley SB. Biomarkers. Mol Aspects Med 2002;23:101-208.
35. Peng J, Jones GL, Watson K. Stress proteins as biomarkers of oxidative stress: Effects of antioxidant supplements. Free Radic Biol Med 2000;28(11):1598-1606.
36. Ishizuka K, Kimura T, Yoshitake J, Akaike T, Shono M, Takamatsu J, Katsuragi S, Kitamura T, Miyakawa T. Possible assessment for antioxidant capacity in Alzheimer's disease by measuring lymphocyte heme oxygenase-1 expression with real time RT-PCR. Ann N Y Acad Sci 2002;977:173-178.
37. Antoine JM, Diplock AT. Validation of markers for their relevance to health and disease. Free Radic Res 2001;33: S117-S120.