Synthesis of 14C-labeled and tritiated AMPA potentiator LY450108

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 48, Issue 2, 2005, Pages 85-100

  Czeskis, Boris A ^a   O'Bannon, Douglas D ^a   Wheeler, William J ^a   Clodfelter, Dean K ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

AMPA potentiator; Asymmetric synthesis; Carbon 14 labeled; LY450108

Indexed keywords

ALKYLATION; CARBON; STEREOCHEMISTRY; SYNTHESIS (CHEMICAL);

ACID DERIVATIVE; AMPA POTENTIATOR; ASYMMETRIC SYNTHESIS; CARBON 14; CARBON-14 LABELED; CHIRAL CENTERS; CHIRAL OXAZOLIDINONES; DIASTEREOSELECTIVE; LY450108; PRIMARY ALCOHOLS;

CHLORINE COMPOUNDS;

2 [2 (3,5 DIFLUOROBENZOYLAMINO)PHENYL] 1 (2 PROPANESULFONAMIDO)PROPANE; 2 [2 (3,5 DIFLUOROBENZOYLAMINO)PHENYL] 1 (2 PROPANESULFONAMIDO)PROPANE C 14; 2 [4 (3,5 DIFLUOROBENZOYLAMINO)PHENYL] 1 (2 PROPANESULFONAMIDO)PROPANE H 3; AMPA RECEPTOR AGONIST; CARBON 14; LY 450108; TRITIUM; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; CHEMICAL MODIFICATION; CHEMICAL REACTION; CHIRALITY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; ISOTOPE LABELING; METHYLATION; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 14644446062     PISSN: 03624803     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlcr.899     Document Type: Article

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