Involvement of the p38 mitogen-activated protein kinase signal transduction pathway in burns-induced lung injury

Chinese Medical Journal

Volumn 118, Issue 4, 2005, Pages 329-332

  Chen, Xu Lin ^a   Xia, Zhao Fan ^b   Wei, Duo ^b   Wang, Yong Jie ^a   Wang, Chang Rong ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Adult; Burns; p38 mitogen activated protein kinase; Respiratory distress syndrome

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE P38;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; BODY SURFACE; BURN; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; HISTOPATHOLOGY; LUNG BLOOD VESSEL; LUNG FLUID; LUNG INJURY; LUNG PERFUSION; MALE; MICROVASCULATURE; NONHUMAN; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SKINFOLD THICKNESS; STATISTICAL ANALYSIS; WATER CONTENT; WESTERN BLOTTING;

ANIMALS; BODY WATER; CAPILLARY PERMEABILITY; HYDRAZONES; LUNG; MALE; MAP KINASE SIGNALING SYSTEM; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATORY DISTRESS SYNDROME, ADULT;

EID: 14644440875     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Herndon DN, Barrow RE, Linares HA, et al. Inhalation injury in burned patients: effects and treatment. Burns 1988;14:349-356.
2. Ono K, Han J. The p38 signal transduction pathway: activation and function. Cell Signal 2000;12:1-13.
3. Yang J, Murphy C, Denham W, et al. Evidence of a central role for p38 map kinase induction of tumor necrosis factor alpha in pancreatitis-associated pulmonary injury. Surgery 1999;126:216-222.
4. Yoshinari D, Takeyoshi I, Koibuchi Y, et al. Effects of a dual inhibitor of tumor necrosis factor-alpha and interleukin-1 on lipopolysaccharide-induced lung injury in rats: involvement of the p38 mitogen-activated protein kinase pathway. Crit Care Med 2001;29:628-634.
5. Otani Y, Takeyoshi I, Koibuchi Y, et al. The effect of FR167653 on pulmonary ischemia-reperfusion injury in rats. J Heart Lung Transplant 2000;19:377-383.
6. Gloor B, Blinman TA, Rigberg DA, et al. Kupffer cell blockade reduces hepatic and systemic cytokine levels and lung injury in hemorrhagic pancreatitis in rats. Pancreas 2000;21:414-420.
7. Wood CE, Giroux D, Gridley K. Fetal brain regional responses to cerebral hypoperfusion: modulation by estrogen. Brain Res 2003;993:84-89.
8. Han J, Lee JD, Bibbs L, et al. A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 1994;265:808-811.
9. Clark AR, Dean JL, Saklatvala J. Post-transcriptional regulation of gene expression by mitogen-activated protein kinase p38. FEBS Lett 2003;546:37-44.
10. Tadros T, Traber DL, Heggers JP, et al. Effects of interleukin-1 alpha administration on intestinal ischemia and reperfusion injury, mucosal permeability, and bacterial translocation in burn and sepsis. Ann Surg 2003;237:101-109.
11. Horton JW. Free radicals and lipid peroxidation mediated injury in burn trauma: the role of antioxidant therapy. Toxicology 2003;189:75-88.
12. Shimizu S, Tanaka H, Sakaki S, et al. Burn depth affects dermal interstitial fluid pressure, free radical production, and serum histamine levels in rats. J Trauma 2002;52-683-687.
13. Kayyali US, Donaldson C, Huang H, et al. Phosphorylation of xanthine dehydrogenase/oxidase in hypoxia. J Biol Chem 2001;276:14359-14365.
14. Ballard-Croft C, Horton JW. Sympathoadrenal modulation of stress-activated signaling in burn trauma. J Burn Care Rehabil 2002;23:172-182.
15. Milligan ED, O'Connor KA, Armstrong CB, et al. Systemic administration of CNI-1493, a p38 mitogen-activated protein kinase inhibitor, blocks intrathecal human immunodeficiency virus-1 gp120-induced enhanced pain states in rats. J Pain 2001;2:326-333.
16. Arcaroli J, Yum HK, Kupfner J, et al. Role of p38 MAP kinase in the development of acute lung injury. Clin Immunol 2001;101:211-219.