Update on topical wound medications

Clinical Techniques in Equine Practice

Volumn 3, Issue 2 SPEC. ISS., 2004, Pages 164-172

  Farstvedt, Ellis ^a,b   Stashak, Ted S ^a   Othic, Ashlee ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b USA   (United States)

Author keywords

Antibiotics; Antiseptics; Cleansers; Herbs; Medicants; Topical; Wound

Indexed keywords

ALOE VERA EXTRACT; ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; BACITRACIN; CEFAZOLIN; CHLORHEXIDINE; COMFREY EXTRACT; CORTICOSTEROID; CRYSTAL VIOLET; DOXYCYCLINE; EUCALYPTUS EXTRACT; GALLIUM NITRATE; GENTAMICIN; HERBACEOUS AGENT; HYDRASTIC CANADENSIS EXTRACT; HYDROGEN PEROXIDE; HYPOCHLORITE SODIUM; JOJOBA EXTRACT; LAMIN; LANOLIN; NEOMYCIN; NITROFURAL; PHENYTOIN; POLYMYXIN B; POVIDONE IODINE; PROPOLIS; SULFADIAZINE SILVER; TEA CLENZ ANTI MICROBIAL CONCENTRATE; TEA TREE OIL; THYMUS EXTRACT; TRIPEPTIDE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ALOE VERA; ANTIMICROBIAL ACTIVITY; DEBRIDEMENT; DRUG ACTIVITY; DRUG EFFECT; DRUG EFFICACY; DRUG POTENTIATION; EPITHELIZATION; HONEY; HYPERTHYROIDISM; HYPOTHYROIDISM; NONHUMAN; REVIEW; SKIN ALLERGY; SKIN ULCER; SURGICAL WOUND; THYROTOXICOSIS; VETERINARY MEDICINE; WOUND; WOUND CARE; WOUND CONTRACTION; WOUND HEALING; WOUND INFECTION; YEAST;

EQUIDAE; EQUUS CABALLUS;

EID: 14644440505     PISSN: 15347516     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.ctep.2004.08.003     Document Type: Article

References (101)

1. http://www.bccresearch.com/editors/RC-077N.html
2. D. Knottenbelt Basic wound management Knottenbelt Handbook of Equine Wound Management 2003 Elsevier Science Limited Edinburgh 39 77
3. G.T. Rodeheaver Wound cleansing, wound irrigation, wound disinfection D.L. Krasner G.T. Rodeheaver G.R. Sibbald Chronic Wound Care A Clinical Source Book for Healthcare Professionals 2001 HMP Communications Wayne, PA 369 383
4. R.F. Edlich, I.R. Schmolka, M.P. Prusak The molecular basis for toxicity of surfactants in surgical wounds. 1. EO PO block polymers J Surg Res 14 1973 277 284
5. T.S. Stashak Equine Wound Management 1991 Lea & Febiger Philadelphia, PA 19 51
6. S.F. Swain Topical wound medications A review J Am Vet Med Assoc 190 1987 1588 1593
7. F.W. Peter, H. Li-Peuser, P.N. Vogt The effect of wound ointments on tissue microcirculation and leukocyte behaviour Clin Exp Dermatol 27 2002 51 55
8. W.H. Hugo, J.M. Newton The antibacterial activity of a complex of iodine and a non-ionic surface active agent J Pharm Pharmacol 16 1964 189 197
9. T. Rath, G. Meissl Induction of hyperthyroidism in burn patients treated topically with povidone-iodine Burns Incl Therm Inj 14 1988 320 322
10. K.R. Shetty, E.H. Duthie Jr Thyrotoxicosis induced by topical iodine application Arch Intern Med 150 1990 2400 2401
11. K. Nobukuni, N. Hayakawa, R. Namba The influence of long-term treatment with povidone-iodine on thyroid function Dermatology 195 suppl 2 1997 69 72
12. G. Rodeheaver, W. Bellamy, M. Kody Bacterial activity and toxicity of iodine-containing solutions in wounds Arch Surg 117 1982 181 186
13. H.N. Prince, W.S. Nonemaker, R.C. Norgard Drug resistance studies with topical antiseptics J Pharm Sci 67 1978 1629 1631
14. S. Lozier, E. Pope, J. Berg Effects of four preparations of 0.05% chlorhexadine diacetate on wound healing in dogs Vet Surg 21 1992 107 112
15. E.I. Amber, R.A. Henderson, S.F. Swaim A comparison of antimicrobial efficacy and tissue reaction of four antiseptics on canine wounds Vet Surg 12 1983 63 68
16. I.R. Sanchez, S.F. Swaim, K.E. Nusbaum Effects of chlohexidine diacetate and povidone-iodine on wound healing in dogs Vet Surg 17 1988 291 295
17. A. Carrel, G. Dehelly The Treatment of Infected Wounds 1917 Hoeber New York, NY
18. S.M. Lozier Topical wound therapy J. Harari Surgical Complications and Wound Healing in the Small Animal Practice 1993 WB Saunders Co Philadelphia, PA 63 68
19. J.M. Liptak An overview of the topical management of wounds Aust Vet J 75 1997 408 413
20. W. Lineaweaver, R. Howard, D. Soucy Cellular and bacterial toxicities of topical antimicrobials Arch Surg 120 1985 267 270
21. R.J. Lemarie, G. Hosgood Antiseptics and disinfectants in small animal practice Comp Contin Educ 17 1995 1339 1351
22. L.L. Southwood, G.M. Baxter Instrument sterilization, skin preparation, and wound management Vet Clin North Am Equine Pract 12 1996 173 194
23. M.J. Muller, M.A. Hollyoak, S. Moaveni Retardation of wound healing by silver sulfadiazine is reversed by Aloe vera and nystatin Burns 29 2003 834 836
24. D.B. Berry, K.E. Sullins Effects of topical application of antimicrobials and bandaging on healing and granulation tissue formation in wounds of the distal aspect of the limbs in horses Am J Vet Res 64 2003 88 92
25. L.S. Beck, L. Deguzman, W.P. Lee TGF-beta 1 accelerates wound healing Reversal of steroid-impaired healing in rats and rabbits Growth Factors 5 1991 295 304
26. E.E. Peaccock Jr Wound Repair (ed 3). 1984 WB Saunders Philadelphia, PA 122
27. I. Hashimoto, H. Nakanishi, Y. Shono Angiostatic effects of corticosteroid on wound healing of the rabbit ear J Med Invest 49 2002 61 66
28. D.A. Wilson, E.H. Adelstein, K.G. Keegan In vitro and in vivo effects of activated macrophage supernatant on distal limb wounds in ponies Am J Vet Res 57 1996 1220 1224
29. C. Rund Alternative topical therapies for wound care D.L. Krasner G.T. Rodeheaver G.R. Sibbald Chronic Wound Care A Clinical Source Book for Healthcare Professionals 2001 HMP Communications Wayne, PA 329 340
30. J.M. Schmidt, J.S. Greenspoon Aloe vera dermal wound gel is associated with a delay in wound healing Obstet Gynecol 78 1991 115 117
31. L.M. Cera, J.P. Heggers, M.C. Robson The therapeutic efficacy of Aloe vera cream in thermal injuries Two reports J Am Anim Hosp Assoc 16 1980 768 772
32. L. Langmead, R.J. Makins, D.S. Ramptom Anti-inflammatory effects of aloe vera gel in human colorectal mucosa in vitro Aliment Pharmacol Ther 19 2004 521 527
33. D. Duansak, J. Somboonwong, S. Patumraj Effects of aloe vera on leukocyte adhesion and TNF-alpha and IL-6 levels in burn wound rats Clin Hemorheol Microcirc 29 2003 239 246
34. Witherspoon E: Healing Tree Products, Inc., McMinnville, Oregon (pamphlet and personal comm.) 2004
35. R.A. Heckman The bacteriocidal properties of comfrey (Symphytum officinale) herbal extracts 2004 Department of Zoology, Brigham Young University from Pavia Sales Group, Inc. (pamphlet)
36. Karavaev VA, Solntsev MK, Iurina TP: Antifungal activity of aqueous extracts from the leaf of cowparsnip and comfrey. Izv Akad Ser Biol 4 (abstr)
37. Al-Saimary IE, Bakr SS, Jaffar T,, et al. Effects of some plant extracts and antibiotics on Pseudomonas aeroginosa isolated from various burn cases. Saudi Med J 23:7 (abstr)
38. A.K. Agrawal Therapeutic efficacy of an herbal gel for skin affections in dogs Ind Vet J 74 1997 417 419
39. V. Bhagwat, S.K. Mitra, T. Suryanarayana Therapeutic efficacy of a herbal formulation "Scavon" on the wound healing in cattle Ind Vet J 77 2000 636 637
40. K.V. Bansod Efficacy of topicure on wounds in canines Ind Vet J 80 2003 1300 1301
41. B.H.G. Pearse, S.K.J. Peucker Comparison of a liquid and a powder insecticidal dressing to aid healing and prevent flystrike of mulesing wounds in lambs Aust Vet J 68 1991 163 164
42. Hwang BW, Roberts SK, Chadwick LR,, et al. Antimicrobial constituents from Goldenseal (the rhizomes of Hydrastix Canadensis) against selected oral pathogens. Planta Med 69:7 (abstr)
43. M.J. Scott, M.J. Scott Jr Jojoba oil J Am Acad Dermatol 6 1982 545
44. F. Wantke, W. Hemmer, M. Gotz Contact dermatitis from jojoba oil and myristyl lactate/maleated soybean oil Contact Dermatits 34 1996 71 72
45. J. Pavia Pavia Natural Wound Care Cream 2004 Pavia Sales Group, Inc Minnetonka, MN (pamphlet and personal commun.)
46. S. Stepanovic, N. Antic, I. Dakic In vitro antimicrobial activity of propolis and synergism between propolis and antimicrobial drugs Microbiol Res 158 2003 353 357
47. Krol W, Scheller S, Shani J,, et al. Synergistic effect of propolis and antibiotics on the growth of staphylococcus aureus. Arzneimittelforschung 43:5 (abstr)
48. S. Ozen, O. Akyol, M. Iraz Role of caffeic acid phenethyl ester, an active component of popolos, against cisplatin-induced nephrotoxocity in rats J Appl Toxicol 24 2004 27 35
49. Scheller S, Wilczok T, Imielski S,, et al. Free radical scavenging by ethanol extract of propolis. Int J Radiat Biol 57:3 (abstr)
50. Krol W, Czuba Z, Scheller S,, et al. Anti-oxidant property of ethanolic extract of propolis (EEP) as evaluated by inhibiting the chemiluminescence oxidation of luminal. Biochem Int 21:4 (abstr)
51. K.A. Hammer, C.F. Carson, T.V. Riley Antifungal activity of the components of Melaleuca alternifolia (tea tree) oil J Appl Microbiol 95 2003 853 860
52. Olivia B, Piccirilli E, Ceddia T,, et al. Antimycotic activity of Melaleuca alternifolia essential oil and its major components. Lett Appl Microbiol 37:2 (abstr)
53. K. Takarada, R. Kimisuka, N. Takahashi A comparison of the antibacterial efficacies of essential oils against oral pathogens Oral Microbiol Immunol 19 2004 61 64
54. Pina-Vaz C, Rodrigues AG, Pinto E,, et al. Antifungal activity of Thymus oils and their major compounds. J Eur Acad Dermatol Venereol 18:1 (abstr)
55. A. Nostro, A.R. Blanco, M.A. Cannatelli Susceptibility of methicillin-resistant staphylococci to oregano essential oil, carvacrol and thymol FEMS Microbiol Lett 230 2004 191 195
56. A.L. Bertone, K.E. Sullins, T.S. Stashak Effect of wound location and the use of topical collagen gel on exuberant granulation tissue formation and wonud healing in the horse and pony Am J Vet Res 46 1985 1438 1444
57. K.A. Jacobs, D.J. Leach, P.B. Fretz Comparative aspects of the healing of excisional wound on the legs and body of horses Vet Surg 13 1984 83 90
58. P. Nathan, E.J. Law, J.D. Ogle Proteolytic enzyme activity in the granulation tissue of the human burn wound J Trauma 16 1976 912 918
59. G. Rodeheaver, D. Marsh, M.T. Edgerton Proteolytic enzymes as adjuncts to antimicrobial prophylaxis of contaminated wounds Am J Surg 129 1975 537 544
60. R.P. Hummel, P.D. Kautz, B.G. MacMillan The continuing problem of sepsis following enzymatic debridement of burns J Trauma 14 1974 572 579
61. W. Westerhof, F.C. Jansen, F.S. de Wit Controlled double-blind trial of fibrinolysin-desoxyribonuclease (Elase) solution in patients with chronic leg ulcers who are treated before autologous skin grafting J Am Acad Dermatol 17 1987 32 39
62. J.S. Chapple Elase and wound debridement N Z Med J 97 1984 701
63. E.K. Kastrup B.R. Olin S.I. Connell S.K. Hebel Facts and Comparisons 1989 St. Louis, MO Facts and Comparisons
64. J.E.F. Reynolds MarindaleL the extra pharmacopoeia 1980 Pharmaceutical Press 315
65. T.A. Noble, D.S. Carr, M.F. Gonzales Use of a trypsin, Peru balsam, and castor oil spray on the oral mucosa case report and review of the literature Pharmacotherapy 9 1989 386 388
66. V.E. Yucel, J.V. Basmajian Decubitus ulcers healing effect of an enzymatic spray Arch Phys Med Rehabil 55 1974 517 519
67. C.S. Thomas, S.A. Scott, D.J. Galanis Box jellyfish (Carybdea alata) in Waikiki. The analgesic effect of sting-aid, Adolph's meat tenderizer and fresh water on their stings A double-blinded, randomized, placebo-controlled clinical trial Hawaii Med J 60 2001 205 207
68. U. Wollina, K. Karte, C. Herold Biosurgery in wound healing-the renaissance of maggot therapy J Eur Acad Dermatol Venereol 14 2000 285 289
69. R.B. Bigbie, J. Schumacher, S.F. Swain Effects of amnion and live yeast cell dericative on second-intention healing in horses Am J Vet Res 52 1991 1376 1382
70. A. Kingsley The use of honey on the treatment of infected wounds case studies Brit J Nurs 10 suppl 22 2001 S13 S16 S18, S20, (abstr.)
71. K.A. Mathews, A.G. Binnington Wound management using honey Compend Contin Educ 24 2002 53 60
72. R.A. Cooper, P.C. Molan, K.G. Harding The sensitivity to honey of Gram-positive cocci of clinical significance isolated from wounds J Appl Microbiol 93 2002 857 863
73. L.M. Bang, C. Buntting, P. Molan The effect on dilution on the rate of hydrogen peroxide production in honey and its implication for wound healing J Altern Complement Med 9 2003 267 273
74. S. Frankel, G.E. Robinson, M.R. Berenbaum Antioxidant capacity and correlated characteristics of 14 unifloral honeys J Apic Res 37 1998 27 31
75. P.C. Molan The role of honey in the management of wounds J Wound Care 8 1999 415 418
76. A.J. Tonks, R.A. Cooper, K.P. Jones Honey stimulates inflammatory cytokine production from monocytes Cytokine 21 2003 242 247
77. P.E. Lusby, A. Coombes, J.M. Wilkinson Honey A potent agent for wound healing? J Wound Ostomy Continence Nurs 29 2002 273 274
78. O.A. Moore, F. Campbell, K. Seers Systematic review of the use of honey as a wound dressing BMC Complement Altern Med 1 2001 Epub (http://www. biomedcentral.com/1472-6882/1/2)
79. M. Chvapil, J.A. Gaines, T. Gilman Lanolin and epidermal growth factor in healing of partial thickness pig wounds J Burn Care Rehabil 9 1988 279 284
80. V. Dodd, C. Chalmers Comparing the use of hydrogel dressings to lanolin ointment with lactating mothers J Obstet Gynecol Neonatal Nurs 32 2003 486 494
81. A.K. Pendse, A. Sharma, A. Sodani Topical phenytoin in wound healing Int J Dermatol 32 1993 214 217
82. Dehghani S, Abrishami A: Effect of phenytoin on wound healing in rabbits. Indian J Vet Surg. 14:1 (abstr)
83. J. Gonclaves, N. Wasif, D. Esposito Gallium nitrate accelerates partial thickness wound repair and alters keratinocyte integrin expression to favor a motile phenotype J Surg Res 103 2002 134 140
84. A. Bjornberg, H. Mobacken Necrotic skin reactions caused by 1 percent genetian violet and brilliant green Acta Derm Venerol 52 1972 55 60
85. H. Mobacken, B. Zederfeldt Influence of a cationic triphenlymethan dye on granulation tissue growth in vivo. An experimental study in rats Acta Derm Venerol (Stockh) 53 1973 161 172
86. C. Dealy The Care of Wounds 1994 Blackwell Scientific Publications Oxford 11 17
87. T.J. Ryan Wound healing and current dermatologic dressings Clin Derm 8 1990 21 29
88. M.S. Cupp, S.F. Swaim, T. Amalsadvala Use of a recombinant vasoactive protein (rSVEP) to enhance healing of surgically-created wounds 2004 Dept. Entomolgy and Plant Pathology, Auburn University Alabama
89. First Priority, Inc., 1585 Todd Farm Drive, Elgin IL, 60123 (personal comm.)
90. 2 Cosmeceuticals: Amino-Plex®. Beverly Hills, CA. (pamphlet)
91. 2 Cosmeceuticals, Beverly Hills, CA (pamphlet)
92. Addison Biological Laboratory, Inc.: http://addisonlabs.com/ Zn7EquineWoundCare.htm, 2004
93. R.B. Turner, W.E. Cetnarowski Effect of treatment with zinc gluconate or zinc acetate on experimental and natural colds Clin Infect Dis (Epub) 31 2000 1202 1208
94. I. Tenaud, I. Sainte-Marie, O. Jumbou In vitro modulation of keratinocyte wound healing integrins by zinc, copper, and manganese Br J Dermatol 140 1999 26 34
95. R.L. Ruberg Role of nutrition in wound healing Surg Clin North Am 64 1984 705 714
96. P. Tarnow, M. Agren, H. Steenfos Topical zinc oxide treatment increases endogenous gene expression of insulin-like growth factor-1 in granulation tissue from porcine wounds Scand J Plast Reconstr Surg Hand Surg 28 1994 255 259
97. M.S. Agren, M. Chvapil, L. Franzen Enhancement of re-epithelialization with topical zinc oxide in porcine partial-thickness wounds J Surg Res 50 1991 101 105
98. S.F. Swaim What's new in wound management 2003 117 118 Proceedings of the North American Veterinary Conference; Small animal
99. D. MacKay, A.L. Miller Nutritional support for wound healing Altern Med Rev 8 2003 359 377
100. Susaman N, Yalcin S, Ilhan N,, et al. The effect of vitamin E on histopathologic healing and lipid peroxidation levels in experimentally induced traumatic tympanic membrane perforations. Kulak Burun Borgaz Ihtis Derg 10:3 (abstr)
101. L.S. Baumann, J. Spencer The effects of topical vitamin E on the cosmetic appearance of scars Dermatol Surg 25 1999 311 315