Manufacturing techniques of biodegradable implants intended for intraocular application

Drug Delivery: Journal of Delivery and Targeting of Therapeutic Agents

Volumn 12, Issue 2, 2005, Pages 109-116

  Fialho, Sílvia Ligório ^a   Da Silva Cunha, Armando ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

Compression; Hot Molding; Implant; Polyglycolic Acid; Polylactic Acid; Prolonged Release

Indexed keywords

DEXAMETHASONE ACETATE; POLYGLACTIN; POLYLACTIC ACID;

ARTICLE; COMPRESSION; DEGRADATION; DIFFERENTIAL SCANNING CALORIMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMPLANT; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SUSTAINED DRUG RELEASE; VITREORETINOPATHY;

ABSORBABLE IMPLANTS; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; EYE;

EID: 14644415603     PISSN: 10717544     EISSN: None     Source Type: Journal    
DOI: 10.1080/10717540590921432     Document Type: Article

References (19)

1. Clas, S. D., Dalton, C. R., and Hancock, B. 1999. Differential scanning calorimetry: applications in drug development. Pharm. Sci. Technol. Today 2(8):311-320.
2. Dash, A. K., and Cudworth II, G. C. 1998. Therapeutic applications of implantable drug delivery systems. J. Pharmacol. Toxicol. Methods 40:1-12.
3. Hashizoe, M., Ogura, Y., Kimura, H., Moritera, T., Honda, Y., Kyo, M., Hyon, S.-H., and Ikada, Y. 1994. Scleral plug of biodegradable polymers for controlled drug release in the vitreous. Arch. Ophthalmol. 112:1380-1384.
4. Hatakeyama, T., and Quinn, F. X. 1994. Applications of thermal analysis. In Thermal Analysis - Fundamentals and Applications to Polymer Science, eds. Hatakeyama, T., and Quinn, F. X. 65-105. London: John Willey & Sons Ltd.
5. Jain, R. A. 2000. The manufacturing techniques of various drug loaded biodegradable poly (lactide-co-glycolide) (PLGA) devices. Biomaterials 21:2475-2490.
6. Kimura, H., and Ogura, Y. 2001. Biodegradable polymers for ocular drug delivery. Ophthalmologica 215:143-155.
7. Kimura, H., Ogura, Y., Hashizoe, M., Nishiwaki, H., Honda, Y., and Ikada, Y. 1994. A new vitreal drug delivery system using an implantable biodegradable polymeric device. Invest. Ophthalmol. Vis. Sci. 35(6):2815-2819.
8. Kunou, N., Ogura, Y., Hashizoe, M., Honda, Y., Hyon, S. H., and Ikada, Y. 1995. Controlled intraocular delivery of ganciclovir with use of biodegradable scleral implant in rabbits. J. Control. Rel. 37:143-150.
9. Kunou, N., Ogura, Y., Yasukawa, T., Kimura, H., Miyamoto, H., Honda, Y., and Ikada, Y. 2000a. Long-term sustained release of ganciclovir from biodegradable scleral implant for the treatment of cytomegalovirus retinitis. J. Control. Rel. 68:263-271.
10. Kunou, N., Ogura, Y., Honda, Y., Hyon, S. H., and Ikada, Y. 2000b. Biodegradable scleral implant for controlled intraocular delivery of betamethasone phosphate. J. Biomed. Mater. Res. 51(4):635-641.
11. Park, T. G. 1995. Degradation of poly(lactic-co-glycolic acid) microspheres: effect of copolymer composition. Biomaterials 16:1123-1130.
12. Peyman, G. A., and Ganiban, G J. 1995. Delivery systems for intraocular routes. Adv. Drug Deliv. Rev. 16:107-123.
13. Ramchandani, M., Pankaskie, M., and Robinson, D. 1997. The influence of the manufacturing procedure on the degradation of poly(lactide-co-glycolide) 85:15 and 50:50 implants. J. Control. Rel. 43:161-173.
14. Rothen-Weinhold, A., Besseghir, K., Vuaridel, E., Sublet, E., Oudry, N., Kubel, F., and Gurny, R. 1999. Injection-molding versus extrusion as manufacturing technique for the preparation of biodegradable implants. Eur. J. Pharm. Biopharm. 48:113-121.
15. Tan, D. T. H., Chee, S., Lim, L., and Lim, A. S. M. 1999. Randomized clinical trial of a new dexamethasone delivery system (surodex) for treatment of postcataract surgery inflammation. Ophthalmology 106(2):223-231.
16. Tan, D. T. H., Chee, S., Lim, L., Theng, J., and Ede, M. L. V. 2001. Randomized clinical trial of surodex steroid drug delivery system for cataract surgery-anterior versus posterior placement of two surodex in the eye. Ophthalmology 108(12):2172-2181.
17. United States Pharmacopeia. 24 ed. - NF 19. (USP 24) Rockville, MD: United States Pharmacopeial Convention, 2000. CD-ROM (Insight Publishing Productivity).
18. Witt, C., Mäder, K., and Kissel, T. 2000. The degradation, swelling and erosion properties of biodegradable implants prepared by extrusion or compression moulding of poly(lactide-co-glycolide) and ABA triblock copolymers. Biomaterials 21:931-938.
19. Zhou, T., Lewis, H., Foster, R. E., and Schwendeman, S. P. 1998. Development of a multiple-drug delivery implant for intraocular management of proliferative vitreoretinopathy. J. Control. Rel. 55:281-295.