Block of Na+ and K+ currents in rat ventricular myocytes by quinacainol and quinidine

Clinical and Experimental Pharmacology and Physiology

Volumn 32, Issue 1-2, 2005, Pages 60-65

  Pugsley, Michael K ^a   Walker, Michael J A ^b   Saint, David A ^c  

^a FOREST RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

Cardiac electrophysiology; Class I antiarrhythmic; Potassium current; Quinacainol; Quinidine; Sodium current

Indexed keywords

QUINACAINOL; QUINIDINE; VOLTAGE GATED SODIUM CHANNEL;

AMPLITUDE MODULATION; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ANTIARRHYTHMIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; HEART ELECTROPHYSIOLOGY; HEART MUSCLE CELL; HEART VENTRICLE; HYPERPOLARIZATION; MALE; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; RAT; SODIUM CURRENT; STEADY STATE;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHYSIOLOGY; HEART VENTRICLES; MALE; MEMBRANE POTENTIALS; MYOCYTES, CARDIAC; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; QUINIDINE; QUINOLINES; RATS; RATS, WISTAR; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; SOLUTIONS;

EID: 14644408663     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2005.04149.x     Document Type: Article

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